ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

An external cardiac pacemaker was developed and was used to stimulate the heart electrically in a series of patients with recent Stokes-Adams syncope. It resuscitated patients from attacks due to ventricular standstill; it maintained an adequate circulation during persistent ventricular standstill; and it prevented the recurrence of irregular ventricular tachycardia. Several patients have now survived for many months without recurrent syncope. Such long survivals suggest that the periods of cardiac disturbance which cause syncope may subside if the patient is kept alive during the crucial period.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Fourteen patients with arteriosclerotic aneurysm of the abdominal aorta are described. Excision of the aneurysm and reconstruction by an aortic homograft have been used in all cases. One patient from whom a ruptured aneurysm was excised, died after operation of uremia. Two other patients died of coronary artery disease after leaving the hospital. The remaining patients are well. Early results with this form of treatment are significantly better than those obtained by less definitive methods used in the past.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Though patients with small atrial septal defects may do well, in certain individuals with large defects operative closure is highly desirable because of the resultant cardiac dysfunction and the poor prognosis without treatment. Extensive efforts in the experimental laboratory have led to the development of a number of methods for the surgical closure of these defects, a number of which have had clinical trial. An earlier method, in which a pericardial pocket was affixed to an incision in the atrial wall and invaginated into the atrial cavity so that its posterior wall could be sutured to the rim of the defect, proved safe and reliable in experimental animals. One case demonstrated, however, that in large human defects the pericardium may not become sufficiently rapidly vascularized to permit its survival. The present experiments have shown that the same technic modified by substitution of a plastic nylon pocket appears entirely satisfactory. In one clinical case it was applied with success. It is suggested that when simpler methods are not applicable this procedure may prove safer and more reliable than certain other methods which have been used.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

The cardiac output has been measured during the immediate post-Valsalva maneuver recovery period in normal subjects, patients with clinically significant mitral stenosis, and patients with alterations of the autonomic nervous system. When compared with the resting value, it was found that normal subjects had a decrease in cardiac output during the immediate post-Valsalva recovery period, while patients with mitral stenosis had an increased output following the same stress. Three patients with alterations of the autonomic nervous system had a variable response. Changes in total peripheral vascular resistance usually were directionally opposite to changes in the cardiac output. The difficulties of attaching clinical significance to a patient's response to the Valsalva maneuver are considered.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

This study represents an effort to distinguish between neurogenic and humoral vasoconstrictive factors in a representative group of hypertensive patients by the response to hexamethonium ganglionic blockade. The correlation between intravenous hexamethonium sensitivity and subsequent treatment response was also determined.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

As a background to the problem of shock associated with acute myocardial infarction, a review of 816 recent consecutive and proved cases has been made. One hundred and sixty-one cases met the arbitrary criteria for the definition of shock. Therefore, shock was found to have occurred in 20 per cent of the patients with myocardial infarction. The mortality was 81 per cent (128 patients died). In the present study, 134 patients with acute myocardial infarction in shock were treated. All of these patients were first treated by strictly routine measures, including digitalis when indicated. Sixty of the 134 patients were relieved by prompt routine therapy given within a three-hour period of time. The remaining 74 patients were treated by (1) retrograde arterial infusion, (2) the newer sympathomimetic drugs such as methoxamine, isopropylnorepinephrine and norepinephrine and (3) other agents such as cholinesterase and cortisone. An evaluation of these methods was made and the over-all mortality of shock as associated with myocardial infarction was reduced from 81 per cent to 48 per cent.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

Autopsy records of estrogen-treated men, castrated women, and women with breast carcinoma were analyzed with reference to the degree of atherosclerotic disease. Findings were then compared with those in similar groups of men and women whose estrogen supply was considered normal. Results obtained suggest: (1) that the male treated with estrogen has less atherosclerosis than the normal male; (2) that the oophorectomized female has an incidence of severe atherosclerosis approaching that of the male; and (3) that the hyperestrogenic female with breast carcinoma has less atherosclerosis than the normal female.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

The new ganglionic blocking agent, pentapyrrolidinium or M&B 2050, appears to have several distinct advantages over hexamethonium in the treatment of severe hypertension. These advantages include longer duration of action, greater potency, less tolerance, less interference with intestinal motility, and, most important, a more uniform response from day to day on oral administration. However, critical adjustment of dosage is necessary and side effects are not infrequent, the most disturbing being postural faintness and impotence.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID

摘要:

A study of the hearts of 107 dogs revealed that the blood supply to the sinoatrial node was from three sources: right coronary artery, left coronary artery, and right internal mammary artery. A dominant pattern of supply was found in 90 hearts. Three variations are described. The importance of arterial anastomoses to the sinus node and their role in the formation of an extracardiac coronary arterial system are discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1954

数据来源: OVID