摘要:

Removal of the epicardium of the dog's heart with 95 per cent phenol permits anastomoses between pericardial vessels and the coronary arteries that are large enough to carry the Schlesinger mass (40 micra or larger). In 18 patients suffering from intractable angina pectoris an operation consisting of phenolization, instillation of talc and pneumonopexy has resulted in consistent relief of pain. The simplicity of the procedure exposes the patient to minimum risk of fresh thrombosis; its effectiveness justifies further trial.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

The response of the intra-arterial pressure to the cold immersion stimulus was studied in 42 healthy young adults, continuous direct (arterial-pressure) recording being used. The average systolic elevation was 22.6 mm. Hg and the average diastolic elevation was 16.3 mm. Hg. The difference between direct and indirect methods of measuring blood pressure was studied in 351 simultaneous determinations in 35 of these young adults. The direct systolic pressure averaged 9.7 mm. Hg higher and the diastolic pressure was 7.3 mm. Hg lower than the indirect measurement.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

The pressor responses to intravenous injections of angiotonin and s-methyliso-thiourea have been studied in 50 hypertensive subjects and 20 normotensive controls. The rises of blood pressure in the two groups were similar, being but slightly greater in the hypertensives. After the blood pressure has been reduced with hexamethonium, however, the pressor responses to angiotonin, s-methyl isothiourea and noradrenaline are much greater in hypertensives than normotensive subjects. The responses under these conditions to all three pressor agents run parallel to each other, suggesting that there is no specific increase in reactivity in hypertensive subjects, either to angiotonin or noradrenaline. It has been concluded that there is evidence of increased reactivity to pressor substances in hypertensive subjects but that this is not demonstrable until the blood pressure control mechanisms have been inactivated by hexamethonium.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

Since it is possible to perform major surgical interventions on patients with lowered prothrombin-proconvertin concentration we have selected a group of patients suffering from mitral stenosis for further evaluation of this prophylactic measure. These patients are highly predisposed to thromboembolic complications. The controllable risk of hemorrhage might, therefore, be preferred to the heavy risk of thrombosis. The results of our investigations indicate a decrease in incidents of thromboembolism. No serious risk of bleeding is apparently introduced when an accurate and sensitive method of estimating the prothrombin level is used in the control of the treatment.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

Cardiovascular collapse accounted for approximately one-third of the deaths from acute poliomyelitis in two epidemics. This syndrome occurred early in the disease and only in cases of bulbar involvement. In all cases there was morphologic involvement of the medulla and in 75 per cent of the cases there was a varying degree of myocarditis. There was a much smaller incidence of less severe myocarditis in the cases dying of other causes. It is suggested that the combination of sustained vasoconstriction arising as a result of the medullary lesion and the presence of interstitial myocarditis leads to circulatory failure and pulmonary edema.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

Patients who have pulmonary stenosis and ventricular septal defect usually have a right-to-left intracardiac shunt. This paper presents hemodynamic and clinical data on 11 patients who have pulmonary stenosis, ventricular septal defect and left-to-right shunts. Four of these patients also have defects in the atrial septum, and three have demonstrable bidirectional shunts. The level and direction of shunts were determined by blood oxygen-saturation data and indicator-dilution studies. Choice of the form of treatment to be used in patients such as these should be based largely on hemodynamic considerations. Many resemble patients with tetralogy of Fallot who have had a successful pulmonary valvotomy.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

"Left ventricular" work can be estimated with great accuracy in cadaver experiments in which both pressure curves and curves of cardiac output at each instant of systole were recorded. Using these accurate estimates as a target, methods have been sought which would permit the estimation of cardiac work from measurements which could be made in the clinic and the accuracy of such methods has been assessed. A method of approximating the left ventricular work has been devised which is so simple that it could be used by any doctor practising medicine.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

In part I was discussed the nature and magnitude of force artefacts in the ballistocardiogram (BCG) arising from coupling the body to ground. The effect of this grounding on the reading of cardiovascular motion, momentum and force was explained, using the simple one-mass dynamics. Part II dealt with the effects on the ballistocardiogram of a second mass, a platform supporting the body. The body itself is a cutoff filter (of the resonant type) by its springy supporting tissues which couple the body and platform masses. In the displacement ballistocardiogram this attenuates the upper frequencies recorded from stiffly sprung platforms, or from the direct-body whatever its coupling to earth. In the acceleration record, the body mass and spring cut off the lower ballistocardiographic frequencies, while platform mass and body-spring cut off the higher frequencies. The size of these errors and their bearing on multilateral recording were discussed.)

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

The minute has given way to the second as an expression of radiographic exposure duration. It is predicted that the millisecond will be the term of the future. Arterial blood velocity exceeds 50 cm. per second. In cardiovascular radiography, especially angiocardiography, maximum detail cannot be achieved unless the x-ray exposure is short enough to "stop" rapid movement. Practical experience indicates that exposures of 3 milliseconds' duration offer an economic alternative to high speed, serial angiocardiography. A method of achieving such exposures consists of a grid-controlled, hightension, switch tube operated in series with the diagnostic x-ray tube.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID

摘要:

Large intravenous doses of sodium borate, given to seven patients with brain tumors, caused development of temporary but consistent hypoxic-type abnormalities in the S-T segments and the T waves of the electrocardiogram. Correlation of these electrocardiographic changes with blood boron concentrations, determined up to 48 hours after boron injection, indicated that the changes were probably the result of damage by boron, present intracellularly in the myocardium. The intracellular concentrations which cause electrocardiographic abnormalities are considered to be of the order of 100 &mgr;g. per milliliter, similar to concentrations which have been shown to inhibit respiration in in vitro myocardial preparations.

ISSN:0009-7322    

出版商:OVID    

年代:1955

数据来源: OVID