ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The diagnosis of cor pulmonale presents considerable difficulty in its earlier stages. Clinical symptoms are not available until the right heart fails and the only reliable sign is right ventricular hypertrophy, which is not easy to demonstrate. The purpose of this investigation is to evaluate electrocardiographic patterns of these patients as a more practical means of diagnosis. Sixty-seven patients with cor pulmonale are included in this study, which endeavors to point out degrees of correlation between various electrocardiographic patterns and clinical factors, such as stages of the disease, its severity, its etiology, and the anatomic changes of the right ventricle. It also evaluates the degrees of specificity of the various patterns encountered in these patients.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Serum lipids were serially determined in 11 patients receiving pentolinium therapy to evaluate changes secondary to blood pressure effects. Substantial reduction in total Cholesterol was observed, which in some cases was independent of the hypotensive effect of the drug. Fat absorption, studied in 6 patients, revealed diminished postprandial lipemia in each as compared to placebo determinations. However, few patients showed appreciable weight change during a year of therapy. The evidence suggests that the serum lipid changes secondary to pentolinium administration are due to a qualitative change in fat absorption.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Pulmonic stenosis unassociated with a ventricular septal defect of significant size is often a complex abnormality. The stenosis may be valvular, infundibular, or both, and may be associated with an atrial septal defect or even with a small ventricular septal defect. Preoperative studies cannot accurately predict these variations. The surgical approach selected for such patients should permit the correction of each of the cardiac defects encountered. That this can be accomplished by means of extracorporeal circulation and open cardiotomy is demonstrated by the presented series of 10 cases without operative mortality.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Administration of a variety of nonfibrinolytic, nonenzymatic substances induces fibrinolysis in man. The most potent materials of this type known at present are purified protein-free pyrogens. Their action after intravenous injection on the human fibrinolytic system, on some of its components, and on the clotting system of 67 individuals has been studied. The possible therapeutic implications are discussed of the marked fibrinolysis.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The wedge and left atrial pressures were compared in 12 subjects with congenital and acquired heart disease; all experiments were carried out with closed chest under basal conditions. A poor correlation between the wedge and left atrial pressures was noted in over half the patients. The wedge pressure is especially inaccurate in mitral stenosis with marked elevations in left atrial pressure.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Pulmonary bleeding in mitral stenosis is not commonly regarded as an indication for operation. A case is reported in which mitral commissurotomy was performed during pregnancy primarily because of recurrent profuse hemoptysis. Some relevant points are briefly discussed.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

Comparison of hemodynamic changes (cardiac output, renal plasma flow, and extremity blood flow) observed during reserpine-induced hypotension with those occurring during pentolinium-induced hypotension suggests better adaptation following reserpine. This difference is believed to be related to the gradation of onset of hypotension. It was found that reserpine-induced hypotension is potentiated by norepinephrine, and pentolinium-induced hypotension by serotonin. Pretreatment with the hypotensive agent increased the pressor response to norepinephrine and serotonin respectively, if the pressor substance was administered before the onset of hypotension.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

The relationship of the left atrial border movements to underlying pressure and volume changes was investigated in individual human subjects with proved mitral insufficiency. Based on these observations, criteria for the recognition of hemodynamically significant mitral insufficiency have been revised. Special emphasis is placed on a rapid inward movement of the atrial wall during the period of early diastolic emptying. Application of these criteria to a group of patients with surgically proved valvular lesions suggests that they are more reliable than those previously described.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID

摘要:

By means of the analytic method of roentgenkymography of Cignolini, 11 typical cases of Wolff-Parkinson-White syndrome were studied. Comparison of the kymographic tracings with the synchronously registered electrocardiogram demonstrated precocious contraction of a limited ventricular area, situated in the left ventricle in the A type and in the right ventricle in the B type.

ISSN:0009-7322    

出版商:OVID    

年代:1958

数据来源: OVID