摘要:

A review of present day knowledge of the pulmonary circulation in man is presented. In particular the state of the lesser circulation in normal man at rest and under conditions of exercise and acute anoxia is defined in detail in order to provide the physiologic background against which to present the accumulated data in patients with certain types of chronic cardiopulmonary diseases.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The effects of the use of Paritol administered intravenously to 35 individuals are herein reported. This synthetic anticoagulant produces a prolongation of the clotting time similar to that produced by heparin but of longer duration, if appropriate dosage is used. As with heparin, at therapeutic clotting time levels, the prothrombin time is slightly prolonged. Certain untoward effects have been noted and are described. Further studies with Paritol appear justified in order to evaluate its usefulness as a rapidly acting anticoagulant.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Observations on bacterial resistance to antibiotics in 64 patients with bacterial endocarditis are reported. Streptococcus endocarditis is contrasted with staphylococcus endocarditis as regards course, bacterial resistance to antibiotics, and mortality. The management of bacterial resistant patients is stressed and particular emphasis is placed upon the role of the newer antibiotics such as aureomycin.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

A new method for the interpretation of conventional electrocardiographic leads is presented. It is based upon evidence that all body surface leads tend to record from the same resultant electrical forces. The various leads write different QRS and T contours in a given case, then, simply because the axis for each of the leads has a different direction in the electrical field and therefore registers different components of these electrical forces. The method has many advantages over "pattern" methods of interpretation. To illustrate its use, a study of QRS vectors is presented with special reference to the SlS2S3pattern.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Diet, particularly the ingestion of cholesterol and fats, has been considered as causally related to the increasing incidence of coronary heart disease and atherosclerosis. This communication presents evidence which is not consonant with this viewpoint. The evidence presented here is based upon dietary and serum cholesterol studies of 97 males who had experienced coronary heart disease prior to the age of 40 and, for purposes of comparison, 146 healthy, nonhospitalized males. The evidence shows clearly that (a) there is virtually no correlation between ingested cholesterol and the level of cholesterol in the serum, and (b) there is virtually no difference, on the average, in the amount of cholesterol ingested by patients of the coronary disease group and the individuals of the control group. A discussion of the "dietary theory" of atherosclerosis is included in this presentation.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

Feeding chicks a mash enriched with 0.25 per cent cholesterol plus 5 per cent cottonseed oil induces a minimal sustained hypercholesterolemia. After 35 weeks of this regimen, birds exhibited a high incidence of gross cholesterol-induced atherosclerosis, particularly prominent in the thoracic aorta. The presence of atherosclerosis in these chicks with minimal diet-induced hypercholesterolemia lends further experimental support to the concept of the relationship of cholesterol in general, and exogenous cholesterol in particular, to the pathogenesis of human atherosclerosis.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The lipotropic factors choline and inositol fail to exert a prophylactic effect against hypercholesterolemia, organ lipidosis and atherogenesis in the cholesterol-fed chick.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The lipotropic factors choline and inositol fail to influence cholesterolemia, lipemia, tissue lipid concentrations, spontaneous and stilbestrol-induced atherosclerosis in the chick.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

In the course of this presentation I hope it has become evident that the professional life of George Brown could well serve as a model for the activities of the American Heart Association, which has made astonishing and gratifying progress in a few years. The advances in physiology, anatomy, surgery and medicine, as related to cardiovascular diseases, are justifiable reasons for pride. Yet pride in the past can produce no results in the future. Progress in the future must be supported by a tripod, such as has supported it in the past; one leg of the tripod is zeal, another is utilization of skill and knowledge, and another is money. We must furnish all three. The unsolved problems are unsolved not only because they are difficult but because we have not yet achieved a coordinated program of investigation. We must abandon all feelings of futility and avoid tedium. I can find no logical reason to believe that any important cardiovascular disease cannot be largely or wholly vanquished. If the conquest of these diseases continues at the rate which characterized the fifteen years just past, within the lifetime of physicians now living there will be no cardiovascular disease which cannot be prevented or corrected. If we remain imbued with untiring resolution to attack vigorously and with persistent zeal the greatest destroyers of health and life in America, such a program will be continued. We must hold forever before ourselves the truism that scientific research is progress.Because this is the George Brown Memorial Lecture, I may appropriately quote from another "Brown," although spelled Browne, Sir Thomas, the author of "Religio Medici," who, in 1643, wrote as follows:"The World which took but six days to make, is like to take six thousand to make out: meanwhile old Truths voted down begin to resume their places, and new ones rise upon us…. Men disparage not Antiquity, who prudently exalt new Enquiries, and make not them the Judges of Truth, who were but fellow Enquirers of it…. Despise not the obliquities of younger ways nor despair of better things whereof there is yet no prospect."

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID

摘要:

The role of the voluntary health agencies in this country is well understood. Tuberculosis, blindness, venereal disease, cancer, and other major public health problems have been attacked by them with notable success, some for as long as 50 years. There is a well established pattern of cooperation with official health agencies and with organized medicine.In its newly added role as a voluntary public health agency, it is important for the American Heart Association to understand these principles and patterns that are discussed here briefly with special emphasis on partnership with nonmedical community leaders, the relationship with the official agencies, including the National Institutes of Health, and on socialized medicine. Good public health work by voluntary organizations is a manifest of the concern of the medical profession with the health of the public and our first bulwark against compulsory government controlled medicine.

ISSN:0009-7322    

出版商:OVID    

年代:1950

数据来源: OVID