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1. |
Marriage and Divorce in Later Life |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 185-187
Gene Cohen,
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ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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2. |
Mania in the Geriatric Patient PopulationA Review of the Literature |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 188-202
Marchant Van Gerpen,
Janet Johnson,
Daniel Winstead,
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摘要:
The diagnosis of mania in the geriatric population is uncommon. However, it comprises significant healthcare utilization and cost requirements, which are expected to increase in the near future with the projected increase in the geriatric population. The authors review literature pertaining to geriatric mania and discuss epidemiology, psychopathology, neuropathology, differential diagnosis, evaluation, treatment, and outcomes. Literature searches were performed by GratefulMed for the years 1960–1997, with secondary- and tertiary-source follow-up. It is clear from this review that geriatric mania is a complex illness with many possible etiologies and treatments. Much more research needs to be conducted in all of the areas reviewed.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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3. |
Studies of Suicide in Later LifeMethodologic Considerations and Research Directions |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 203-210
Jane Pearson,
Eric Caine,
James Lindesay,
Yeates Conwell,
David Clark,
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PDF (166KB)
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摘要:
Later-life suicide is a tragedy that occurs worldwide. Often it is preventable. Here, the authors summarize an international workshop where they review four research approaches to studying putative risk factors: epidemiologic studies of suicidal behaviors, clinic-based follow-up studies, studies of suicide attempters, and psychological autopsy studies. They provide brief descriptions of the approaches, examples of questions best addressed by each approach, and their weaknesses and limitations; they also recommend promising areas for future research and propose opportunities for research that could be conducted cross-nationally.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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4. |
“Probable Early Dementia” |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 211-212
Judith Crossett,
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PDF (78KB)
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ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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5. |
Functional Significance of Mild Cognitive Impairment in Elderly Patients Without a Dementia Diagnosis |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 213-220
Steven Albert,
K. Michaels,
M. Padilla,
G. Pelton,
K. Bell,
K. Marder,
Y. Stern,
D. Devanand,
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PDF (160KB)
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摘要:
The authors investigated differences in functional ability among three groups of subjects who were not diagnosed with dementia: normal control (NC) subjects (n=35); Clinical Dementia Rating Scale (CDRS) score of 0 (minimal impairment; n=26); and CDRS 0. 5 (questionable dementia; n=42). CDRS 0 and 0. 5 patients reported significantly poorer functioning than NCs in household and other activities, but CDRS 0 and CDRS 0. 5 groups did not differ in self-reported functioning. It is likely that CDRS 0. 5 patients overestimated their functional abilities. Correlations between self- and informant reports of functional status were significantly lower in the CDRS 0. 5 group than in the CDRS 0 group, an important finding for clinical management because patients with questionable dementia may actually be more impaired than they admit. Informants' reports or standardized performance-based assessment should be considered in the clinical evaluation of such patients.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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6. |
Comparative Efficacy of Sertraline vs. Fluoxetine in Patients Age 70 or Over With Major Depression |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 221-227
Sanford Finkel,
Ellen Richter,
Cathryn Clary,
Evan Batzar,
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PDF (3344KB)
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摘要:
Using data from a larger 12-week clinical trial, the authors evaluated the comparative efficacy and safety of sertraline (n=42) and fluoxetine (n=33) in patients over age 70 with a diagnosis of major depressive disorder. Similar improvement on measures of depression, including remission of depressive symptoms, was evident, although significantly more sertraline-treated patients achieved a criterion clinical response. Significantly greater improvement for the sertraline group was apparent on the Digit Symbol Substitution Test, but not on two other measures of cognitive functioning. Although there was no difference in the rate of adverse events experienced, fluoxetine-treated patients lost significantly more body weight over the 12-week trial than did sertraline-treated patients, whereas the latter group exhibited significantly more “shaking.”
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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7. |
The Art of Clinical Management in Pharmacologic Trials With Depressed Elderly PatientsLessons from the Pittsburgh Study of Maintenance Therapies in Late‐Life Depression |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 228-234
Mark Miller,
Ellen Frank,
Charles Reynolds,
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摘要:
The authors outline the clinical management methods used in a long-term study of depressed elderly patients and comment on the positive aspects of such interventions on the successful recruitment and retention of subjects. Psychosocial or clinical management (CM) is the “glue” that holds a successful drug trial together. CM is recognized to be an essential element for success in drug trials for geriatric depression. The authors also discuss potentially negative aspects of comprehensive CM, such as those obscuring a psychotherapeutic effect in comparative studies.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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8. |
Patterns of Care for Depressed Older Adults in a Large‐Staff Model HMO |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 235-243
Jürgen Unützer,
Wayne Katon,
Joan Russo,
Gregory Simon,
Terry Bush,
Edward Walker,
Elizabeth Lin,
Michael Van Korff,
Evette Ludman,
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摘要:
The authors examined automated pharmacy and visit data for 502 members of a large-staff model health maintenance organization (HMO) who had been diagnosed with depression and started on antidepressants by their primary-care providers. Older patients (age ≥60; n=110) were less likely than younger adults (age 18–59, n=110) to receive adequate doses of antidepressant medications for 30 or 90 days. Older adults were also less likely than younger adults to receive more than two primary-care visits for depression in the 12 weeks after receiving a new antidepressant prescription and were less likely to receive specialty mental health care in the 6 months after receiving a new antidepressant prescription.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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9. |
Minor Depression After StrokeAn Initial Validation of the DSM‐IV Construct |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 244-251
Sergio Paradiso,
Robert Robinson,
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PDF (846KB)
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摘要:
Using 141 patients with a single left- or right-hemisphere stroke, the authors investigated the distinction between major and minor depression after stroke. Major- and minor-depression patients and nondepressed control patients were compared, and a logistic-regression model suggested that major and minor depressions may be cross-sectionally distinguishable disorders. Minor depression was associated with younger age, left-hemisphere lesion location, and more caudal hemisphere lesions. There was an association between minor depression and pathoanatomical variables, with results generally consistent with the categorical vs. the continuum hypothesis of mood disorders in stroke victims. Authors discuss the significance of damage in left-hemisphere posterior portions of the brain for the development of minor depression after stroke.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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10. |
Cerebrovascular Risk Factors and Depression in Older Primary Care PatientsTesting a Vascular Brain Disease Model of Depression |
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American Journal of Geriatric Psychiatry,
Volume 7,
Issue 3,
1999,
Page 252-258
Jeffrey Lyness,
Eric Caine,
Deborah King,
Yeates Conwell,
Christopher Cox,
Paul Duberstein,
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PDF (147KB)
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摘要:
The authors examined whether cerebrovascular risk factors (CVRFs) are associated with depressive diagnoses and symptoms in 303 primary-care patients age ≥60 years, as would be consistent with a small-vessel brain disease model of later-life depression. CVRFs were not significantly independently associated with major, minor, or subsyndromal depression, late-onset major depression, or overall depressive symptom severity. These data did not support the notion that a small-vessel brain disease model of depression might apply to the majority of older persons with depressive symptoms and syndromes in primary-care settings. Future work should include longitudinal study with larger sample sizes.
ISSN:1064-7481
出版商:OVID
年代:1999
数据来源: OVID
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