摘要:

Needle biopsy was taken from the quadriceps muscles of ten male patients (47.6 ± 8.5 years old) with coronary artery disease (CAD) before and after six weeks of exercise rehabilitation. Patients exercised at 75 % to 85% of maximal cardiac frequency found in a pre-rehabilitation test, I-1/2 hr three days a week. Muscle samples were analyzed for enzymes (μmol/min.g wet weight, mean ± SD) and substrates, and sections were stained for ATPase for fiber typing and PAS-amylase for capillarity assessment and fiber area measurement. After training, maximal energy expenditure increased 24 %. Citrate synthase increased from 9.0 ± 2.9 to 16.0 ± 4.8 (P < 0.01); 3-hydroxyacyl-CoA-dehydrogenase increased from 10.3 ± 2.4 to 13.8 ± 3.1 (P < 0.05); hexokinase increased from 0.67 ± 0.29 to 0.89 ± 0.34 (P < 0.05); and lactate dehydrogenase decreased from 483 ± 226 to 264 ± 122 (P < 0.01). No changes were found in substrate levels. An increase in mean fiber area was found, more marked in Type I fibers (4,794 ± 961 to 6,189 ± 1,267 μm2, P < 0.05). There were no changes in fiber type distribution, or in parameters measuring capillarity, but capillarity was already high before training, probably due to the use of vasodilator drugs. In conclusion, sympton limited training for six weeks in CAD patients produced changes in muscle enzymes and fiber area similar to those produced by training in normal subjects. The changes in oxidative enzymes may account for the increase in maximal energy expenditure found after exercise rehabilitation.

ISSN:0883-9212    

出版商:OVID    

年代:1990

数据来源: OVID

摘要:

To investigate claims that continuous passive motion tables improve physiological and psychological well-being, 94 healthy women were assigned randomly to 12-week programs involving a placebo-control meeting, unsupervised walking, continuous passive motion, and continuous passive motion plus diet. Program outcomes were assessed by analysis of pre- and post-treatment fasting blood chemistry, a graded, symptom-limited maximal exercise test, anthropometric measurements of skinfold and circumferences, and flexibility, as well as anxiety, depression, mood, and somatic distress. Significant improvements were found in cholesterol, weight, suprailiac and weighted skinfold, arm circumference, hip flexibility, and exercise endurance in the active groups. Women in the continuous passive motion plus diet condition had a significant weight loss and improved lipid profile. Committed walkers significantly outperformed women in the continuous passive motion groups on cardiovascular fitness but were more likely to terminate participation in the program prematurely. Results suggested that involvement in continuous passive motion generates positive expectancies for improved physical and psychological well-being, which may improve adherence to health-promoting regimens.

ISSN:0883-9212    

出版商:OVID    

年代:1990

数据来源: OVID

摘要:

Exercise training in orthotopic heart transplant (OHT) patients has been shown to be beneficial. However, appropriate methods effectively guiding exercise intensity are uncertain because of the altered physiologic responses of the denervated heart. This study compares ratings of perceived exertion (RPE) and heart rate (HR) responses in 19 male OHT patients during graded exercise testing (GXT) and training and retrospectively compares two HR-based methods for determining exercise intensity with actual exercise HRs. Graded exercise tests were performed before (Tl) and after (T2) exercise training, and results were compared with exercise HRs during the first (WK-1) and last (WK-F) weeks of training. From Tl to T2, a 17.2 % mean increase in VO2maxwas accompanied by an 11 ± 14 min-1increase in mean peak HR. During exercise training, RPE was maintained between 12 and 14 and treadmill work load increased 39% from WK-1 to WK-F. HR increased from 116 ± 14 beats min-1to 126 ± 16 beats min-1. Exercise training HR usually exceeded 85 % of the peak GXT HR at Tl and T2 and occasionally exceeded 100% of the peak HR measured at Tl. The maximal HR-reserve method generally was more accurate than the straight percent of peak HR method in reflecting the actual HR achieved during exercise training. The data suggest that exercise intensity can be guided by using either RPE or, if a follow-up GXT is performed, a target heart rate range computed using the HR-reserve method.

ISSN:0883-9212    

出版商:OVID    

年代:1990

数据来源: OVID

ISSN:0883-9212    

出版商:OVID    

年代:1990

数据来源: OVID