摘要:

In a previous study Beckman and Beckman [Hum. Hered. 1986;36:254-255] reported a decrease in the Tf C2 frequency with age, from 0.173 in newborns to 0.099 in 70-year-old healthy individuals. The authors suggested a selective disadvantage for Tf C2. In a population from Leipzig (FRG) older people have the highest C2 gene frequency (0.1701 vs. 0.1629 in children < 5 years). The differences are not significant. A dependency of C2 frequency on age seems to remain in question.

ISSN:0001-5652    

DOI:10.1159/000154116

出版商:S. Karger AG    

年代:1993

数据来源: Karger

摘要:

The phenotypes and gene frequencies of three serum protein systems – Hp, GC and C3 – were studied in 184 consecutive patients from all over Greece with colon cancer. Healthy Greeks studied previously in our department served as controls. No significant differences were found between patients and controls concerning GC and C3. Significant differences were found in the Hp system; the frequencies of the Hp*1 gene and the Hp 1-1 phenotype were significantly higher in patients than in contr

ISSN:0001-5652    

DOI:10.1159/000154117

出版商:S. Karger AG    

年代:1993

数据来源: Karger