摘要:

Data are presented on ABO and RhD blood groups in 186 patients suffering from carcinoma of cervix uteri and 274 controls from Delhi, India. A strong association is observed between carcinoma patients and blood group A, and a slightly weaker association with blood group B. There is no significant association with RhD blood group. The available data in other populations confirm the association with ABO blood group.

ISSN:0001-5652    

DOI:10.1159/000154091

出版商:S. Karger AG    

年代:1992

数据来源: Karger

摘要:

Sequence analysis has been performed on the DNA of 13 glucose-6-phosphate dehydrogenase (G6PD) deficient males from Hawaii, 6 of Filipino, 6 of Laotian, and 1 of Chinese extraction. Four different mutations were found: A→T at cDNA nt 835, G→A at nt 871, C→T at nt 1360, and G→A at nt 1388. The mutations at nt 835 and nt 1360 have not been described previously, and the latter, in particular, appears to be relatively common. The nt 1360 mutation changes the same codon as is altered in a previously described mutation, G6PD

ISSN:0001-5652    

DOI:10.1159/000154092

出版商:S. Karger AG    

年代:1992

数据来源: Karger

摘要:

Y-specific polymorphisms were studied in Gujarati Muslim Indians possessing a Y-chromosome pericentric inversion [inv(Y)] in an attempt to prove a common genetic origin for the inversion. The p49a/TaqI and p49a/PvuII haplotypes were determined for 9 normal and 8 inv(Y) Gujarati Muslim men. Men with the inversion possessed identical TaqI and PvuII profiles, as opposed to 7 different TaqI and 8 different PvuII haplotypes observed in the 9 normal men. These results provide conclusive evidence for a common genetic origin of the inverted Y chromosome observed in this Gujarati Muslim community.

ISSN:0001-5652    

DOI:10.1159/000154093

出版商:S. Karger AG    

年代:1992

数据来源: Karger