摘要:

C3 allotyping has been performed on 424 Australian women, 203 with normotensive pregnancies, 161 with hypertensive noneclamptic pregnancies and 60 eclamptic women. The frequency of women heterozygous for ‘rare’ C3 alleles was 1 % in the normotensive women and 3.7% in the hypertensive group. Three out of 25 (12%) of the women with proteinuric hypertension in pregnancy carried ‘rare’ C3 alleles. This suggested the hypothesis that pre-eclampsia/eclampsia is associated with a higher frequency of rare alleles. The sample of 60 eclamptic women collected to test the hypothesis had no rare alleles, refuting the hypothesis. The frequency of the common (C3F, C3S) alleles did not differ significantly between the three groups. We conclude that there is no evidence for any association between susceptibility to eclampsia and allotypes of the C3 complement co

ISSN:0001-5652    

DOI:10.1159/000153755

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Radiation-induced chromosomal damage (after exposure to 1 Gy) in lymphocytes was studied in relation to transferrin C subtype (C1 vs. C2). In 72-hour lymphocyte cultures a significantly increased frequency of cells with radiation induced aberrations was observed in individuals with the transferrin type C2. Thus the results lend some support to the hypothesis that transferrin C2 may act as an enhancer of chromosomal damage.

ISSN:0001-5652    

DOI:10.1159/000153756

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Phenotypes of human red cell esterase D (EsD) were determined in 351 unrelated adults from Serbia (Yugoslavia). The calculated allele frequencies were 0.911 for EsD1 and 0.089 for EsD2.The phenotype distribution was in good agreement with the Hardy-Weinberg equilibrium.

ISSN:0001-5652    

DOI:10.1159/000153757

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Blood samples from two Catalonian populations (North-East of Spain) were analysed for glyoxalase (GLO) I polymorphism. Gene frequencies of GLO1 (0.46 and 0.41) are comparable to those reported for Central-European Caucasoid populations.

ISSN:0001-5652    

DOI:10.1159/000153758

出版商:S. Karger AG    

年代:1988

数据来源: Karger

ISSN:0001-5652    

DOI:10.1159/000153759

出版商:S. Karger AG    

年代:1988

数据来源: Karger