ISSN:0001-5652    

DOI:10.1159/000153809

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

Acid phosphatase (ACP1), esterase D (ESD) and phosphoglucomutase 1 (PGM1) polymorphisms have been studied in Sardinia and the following gene frequencies have been found: ACP1*A = 0.235, ACP1*B = 0.684 and ACP1*C = 0.081; ESD*2 = 0.118 and PGM 1*2 = 0.233. These findings confirm the genetic uniqueness of Sardinians compared to the other Italian and European populations.

ISSN:0001-5652    

DOI:10.1159/000153810

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

One hundred individuals from the city of Bogota and 32 Uitoto Indians from the Colombian Amazonia were HLA-typed. The results showed that the two populations differ significantly in the frequencies of the alleles A28, B15, B39, Bw51, Cw2, Cw3 and DRw52. In general, the Uitoto Indians resemble, in their histocompatibility antigens, other Latin-American Indians so far studied.

ISSN:0001-5652    

DOI:10.1159/000153811

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The frequencies of transferrin C (TF C) subtypes were studied in 315 Finns, 222 Swedish Lapps and in 4,157 conscripts and blood donors from the counties of Norrbotten and Västerbotten in northern Sweden. The Swedish individuals were distributed according to place of birth into 23 subpopulations or regions. A significant heterogeneity between the 23 regions was observed for the TF C1, C2 and C3 genes and for rare genes. Clines were found for the TF Cl and C3 genes and for rare transferrin genes in northern Sweden. The frequencies of the Cl and C3 genes were increasing in the southwestern and northeastern direction, respectively, and the frequency of the rare transferrin genes was increasing in the northern direction. The geographical picture of the C3 gene and of rare transferrin genes could be interpreted in terms of Finnish influence. The frequency of the TF C3 gene in Finland and northern Sweden (14 and 15%) is the highest so far reported in the world. The overall picture of geographical variations of the C1 and C2 genes were not explainable in terms of ethnic influence and may be caused by random differentiation and/or selective forces

ISSN:0001-5652    

DOI:10.1159/000153812

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The correlation between ORM phenotypes in untreated serum and ORM phenotypes after isoelectric focusing of neuraminidase-treated serum is demonstrated. ORM subtypes were determined using isoelectric focusing in immobilized pH gradients. Population genetic studies of ORM polymorphism in the Galician population were also carried out.

ISSN:0001-5652    

DOI:10.1159/000153813

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

The apolipoprotein A-IV (apoA-IV) allele frequencies were determined in 387 adult Finns by immunoblotting after isoelectric focusing of serum. The gene frequencies were: A-IV1 = 0.942 and A-IV2 = 0.058. The phenotypes of 147 mother-child pairs studied were in accordance with the two allelic modes of inheritance. In 2 subjects, a rare apoA-IV variant was found.

ISSN:0001-5652    

DOI:10.1159/000153814

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

A rare variant of complement C4 was found in 2 related individuals. It has the most anodic mobility found to date, no hemolytic activity detected by the overlay technique and a Bgl II RFLP pattern very similar to that of the C4A6 type.

ISSN:0001-5652    

DOI:10.1159/000153815

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

A series of 150 patients with serum hepatitis were examined for the incidence of the Australia antigen (HBsAg) and associations with ABO blood groups, haptoglobin types and occurrence of intestinal serum alkaline phosphatase. Among the patients studied 11.3% were positive for HBsAg. When compared to controls patients with blood group 0 showed a significantly increased risk for serum hepatitis (p < 0.05), while those with group B showed a decreased risk (p < 0.01). The presence of the intestinal fraction of alkaline phosphatase showed a negative association with serum hepatitis (p < 0.01) and there was no significant association between alkaline phosphatase types and ABO groups among the patients. The frequency of the Hp1 gene was significantly increased (p < 0.01) among the patients as compared to controls.

ISSN:0001-5652    

DOI:10.1159/000153816

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

In a Portuguese family, a null allele was found in the Pi system. An apparent ‘exclusion’ of the mother was found to be due to the presence of null alleles in mother and child. A transferrin (Tf) null allele was found in a case of disputed paternity. The mother and putative father were heterozygous for Tf null alleles and the child was homozygous (TfQ0) and presented hypotransferrine

ISSN:0001-5652    

DOI:10.1159/000153817

出版商:S. Karger AG    

年代:1988

数据来源: Karger

摘要:

A panel of 897 randomly chosen Danish donors of blood groups 0 and A was tested for the LKE antigen using a human anti-LKE. In this sample, 78.7% were LKE positive, 20.6% were weakly positive, whereas 0.7% were LKE negative. These phenotype frequencies are similar to those obtained by the first discovered human alloserum and by the monoclonal anti-SSEA-4 in previous studies. The previously reported lower LKE antigen strength in group A versus group 0 donors, and the association of LKE to the P system was confirmed.

ISSN:0001-5652    

DOI:10.1159/000153818

出版商:S. Karger AG    

年代:1988

数据来源: Karger