摘要:

Duch, Dha, a new low frequency antigen on red cells, is inherited as a dominant character segregating independently of Rh, MNSs, Kidd and Y.

ISSN:0001-5652    

DOI:10.1159/000153263

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Complex segregation analysis has shown the red blood cell catechol-O-methyltransferase (COMT) activity in man to be regulated by a major locus (d = 0.27) plus a multifactorial component (H = 0.25). The frequency of the gene which gives low COMT values was 0.46.

ISSN:0001-5652    

DOI:10.1159/000153264

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Eleven Southern African populations (representing European, Asian and Negroid populations) have been typed for the first locus phosphoglucomutase (PGM1) using isoelectric focusing (pH range 5.0–8.0) in acrylamide gels. The gene frequencies of the four common alleles at this locus in these populations were compared to those found previously in European and Negroid populations. Marked differences in gene frequencies were observed : Negroes have a lower PGM↑ compared with Caucasoids due to a lower PGM21- frequency, Indians a relatively high PGM21 due to a higher frequency of the PGM21+ allele. The Afrikaans and Ashkenazim do not differ appreciably from their European counterparts. The appearances of the rarer PGM61 and PGM71 alleles on isoelectric focusing are described and some kinetic properties examined. The PGM22-1, or ‘Atkinson’ phenotype, can also be detected with this te

ISSN:0001-5652    

DOI:10.1159/000153265

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Lactose absorption was studied in 570 healthy adolescent and adult males in Egypt. Employing a field version of the noninvasive hydrogen breath test, 156 (27.4%) lactose absorbers and 414 (72.6%) lactose malabsorbers were identified. The age-specific prevalence of the lactase phenotypes indicated that lactase repression is complete at the age of 14 years in Egyptians. The regional distribution showed significant differences between the Nile Delta and the northern and southern part of Upper Egypt. The existence of a north-south gradient of decreasing frequencies of the hypolactasia gene from the Nile Delta to the Sudan is suggested.

ISSN:0001-5652    

DOI:10.1159/000153266

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

A random sample of unrelated students living in Grotteria and Mammola, two villages of Southern Italy from where most of the Italian patients affected with fucosidosis originate, was analyzed for seven red cell enzyme polymorphisms and seven blood group polymorphisms. The observed gene frequencies are not significantly different from those typical of Southern Italy. Demographic data on the same sample were also collected and indicate isolation and high inbreeding in these villages.

ISSN:0001-5652    

DOI:10.1159/000153267

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The effects of paternal and maternal ages, gestational age and the socio-economic factor of occupation on the sex ratio of twin individuals were analysed using data on 326,140 twin individuals which occurred in Japan during the period from 1955 to 1967 and in 1974. The sex ratio in live births slightly increased with time, whereas the sex ratio in fetal deaths slightly decreased with time. The sex ratio in total births significantly decreased during these years. There might be the possibility of a postponement of late fetal deaths of Japanese twin individuals into the early infant period for the younger maternal age group. The mean sex ratios of twin births during the period from 1960 to 1967 and in 1974 were 0.4995 and 0.5605 for live births and fetal deaths, respectively; the difference is significant. The sex ratio of Japanese twin births is not so high compared with those of Europe and the USA in the recent years. The present study deals with the secular changes of sex ratio of twin births in all of Japan. It also deals with the effect of paternal and maternal ages, birth order, gestational age and the socioeconomic factor of occupation on the sex ratios of twins.

ISSN:0001-5652    

DOI:10.1159/000153268

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

The effects of paternal and maternal ages, gestational age and the socio-economic factor of occupation on the sex ratio of triplet individuals were analysed using data on 4,290 triplet individuals which occurred in Japan during the period from 1955 to 1967 and in 1974. The sex ratios among live births and fetal deaths slightly decreased with time. The decline of the sex ratio was related to the decline of age-specific fertility in older mothers. The mean sex ratio was 0.479 during the period. The sex ratio is not high but similar to those of Europe and the USA. The sex ratio was lower in triplets than in twins or the general population. It seems that predominant male triplets may be selectively aborted in early gestational age compared with that of twins or the general population.

ISSN:0001-5652    

DOI:10.1159/000153269

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Phenotype and gene frequency distributions of placental alkaline phosphatase, esterase D and glyoxalase I among some population groups of Hyderabad, South India are reported. The Pls, Plf and Pli gene frequencies of placental alkaline phosphatase range from 0.725 to 0.76, from 0.16 to 0.19 and from 0.07 to 0.096, respectively. The EsD2 gene frequency ranges from 0.25 to 0.29 and the GLO1 gene frequency ranges from 0.252 to 0.327

ISSN:0001-5652    

DOI:10.1159/000153270

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Gene frequencies for 12 genetic loci have been studied in the district of Almopia in Northern Greece. The frequencies of the G6PD and Hb loci exhibited clinal changes from NW to SE in central Macedonia. In the whole Greek population, the mean proportion of polymorphic loci and the mean heterozygosity were 0.73 and 0.202, respectively. Several stastistically significant differences between Macedonians and Bulgarians were found.

ISSN:0001-5652    

DOI:10.1159/000153271

出版商:S. Karger AG    

年代:1982

数据来源: Karger

摘要:

Three new phenotypes of plasminogen system, named PLG 3–1, PLG 1-M and PLG 1-C, were found in sera from healthy Japanese persons by the agarose gel isoelectric focusing followed by the methods of immunofixation and caseinolysis. The present study indicates that at least the PLG 3 component is genetically determined. The existence of another PLG3 allele is postulate

ISSN:0001-5652    

DOI:10.1159/000153272

出版商:S. Karger AG    

年代:1982

数据来源: Karger