摘要:

Measurement of β-lipoprotein concentration in amniotic fluid is introduced as a new parameter for the early prenatal diagnosis of spina bifida. It was successful in 15 cases of spina bifida, but failed in 5 cases of open spina bifida and 2 cases of closed spina bifida. All assays were performed before the end of the second trimester and most between 15 and 20 weeks of pregnancy. β-lipoprotein was compared with α-fetoprotein and α2-macroglobulin in its effectiveness in diagnosing spina bifida at an early enough date to allow a termination of pregna

ISSN:0001-5652    

DOI:10.1159/000152835

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The distance coefficients between two relatively isolated population groups in Poland, based on various combinations of dermatoglyphic non-measurable characters were estimated. These were compared with the overall dermatoglyphic distance coefficients, estimated separately for left and right, as well as with the serologic distance coefficient, based on ABO, Rh and Duffy blood groups. Dermatoglyphic distance coefficients, estimated from quantitative variables (pattern intensities) using Penrose’s C2H analysis of variance method, were also introduced for a comparison. The differences in frequencies between two populations, separately for each character, were also compared with its heritability values. The genetic interpretation of distance coefficients is fairly complex and the attempts at their evaluation in relation to the within-population variability (intrapopulation distance coefficients) will be presented in a later paper in this series (II

ISSN:0001-5652    

DOI:10.1159/000152836

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

An analysis of the digito-palmar dermatoglyphs obtained from 231 inhabitants of the Island of Hvar, divided into two groups according to some sociocultural differences, is presented. The quantitative features do not reveal heterogeneity between the groups, while some qualitative palmar dermatoglyphic features are statistically significantly different. The results are discussed in the light of the possible influence of some different evolutionary processes.

ISSN:0001-5652    

DOI:10.1159/000152837

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

More than 20 different alleles are so far known at the Pi locus, corresponding to a total variant phenotype frequency of about 10% in most western Europeans. The common phenotype Pi M constitutes the remaining major group. Now it has been possible to identify three subtypes M1, M1M2 and M2, corresponding to the gene products of two common alleles PiM1 and PiM2, segregating as autosomal codominant alleles. Preliminary gene frequencies are reported for eight populations, the PiM2 frequency varying from 0.20 in Maris (USSR) to 0.02 in Bantus (Kenya).

ISSN:0001-5652    

DOI:10.1159/000152838

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

The distribution of the blood group systems ABO, Rhesus, MNSs and P was studied in all or some of 1,007 Singapore Chinese. ABO gene frequencies were found to be consistent with previous studies and did not vary significantly between dialects. An individual of phenotype A2B was detected although the population showed no other evidence for the A2 gene. The possible significance of this observation in terms of weak H alleles in the population is discussed. The frequencies of the MNSs genes are consistent with previous studies. Two subjects appeared to lack the NA component of the N antigen. The frequency of the R1 gene of the Rhesus system was lower than has been detected previously and may relate to dialect differences. No examples of the Cw antigen were detected. The P blood group distribution appears to be subject to regional variation. It is concluded that classification of Chinese into dialect groups is a useful way of assessing genetic heterogeneity.

ISSN:0001-5652    

DOI:10.1159/000152839

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

GLO phenotype distribution and GLO allele frequencies in samples of the Norwegian population and the Lappish minority of Norway are presented. The GLO1 frequency is 0.442 in 216 Norwegians, while it is 0.304 in 184 Lapps; the difference is statistically significant. There are furthermore probably differences in gene frequencies between two main groups of Lapps.

ISSN:0001-5652    

DOI:10.1159/000152840

出版商:S. Karger AG    

年代:1976

数据来源: Karger

摘要:

Three groups of Saraswat Brahmans in Western India and a group of Goan Catholics ethnologically related to Saraswats were studied for various genetic markers. Saraswats have higher A than B with an Rh(D)-negative incidence ranging from 10 to 17%. All the groups have low incidence of G-6-PD deficiency (up to 1 %). Incidence of thalassaemia trait ranges from 1 to 6%. Gm(l) was present in 85–87%. Intergroup differences suggest genetic closeness between the various groups with genetic distance ranging from 0.8 to 1.5. Genetic relationship between Goan Catholics and Chitrapur Saraswats confirms the ethnological and historical evidence of relationship between the two group

ISSN:0001-5652    

DOI:10.1159/000152841

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0001-5652    

DOI:10.1159/000152842

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0001-5652    

DOI:10.1159/000152843

出版商:S. Karger AG    

年代:1976

数据来源: Karger

ISSN:0001-5652    

DOI:10.1159/000152834

出版商:S. Karger AG    

年代:1976

数据来源: Karger