摘要:

Red cell hemolysates from a Finnish population sample (n = 242) were fractionated by isoelectric focusing on polyacrylamide gel, and S-formylglutathione hydrolase (EC 3.1.2.12) was located by activity staining. Polymorphism, which is probably genetically determined, was found. The samples from most persons studied gave one major enzyme band, whereas for 6 persons three enzyme bands were found. The enzyme is a dimer, and the polymorphism observed appears to result from two alleles, FGH1 and FGH2 at an autosomal locus. The frequency found for FGH1 was 0.988.

ISSN:0001-5652    

DOI:10.1159/000153479

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The distribution of anthropometric measurements related to fatness levels is examined to determine if skewness alone accounts for the nonnormality of such measures. A mixture of two normal distributions or a single skewed distribution fit the data significantly better than a single normal in all cases. For maximum hip width, knee diameter, and weight, two skewed distributions give a better fit than one skewed distribution, rejecting the null hypothesis of a single distribution even when skewness is considered. There is evidence for three skewed component distributions for biceps skinfold. Abdomen circumference, upper arm circumference, triceps skinfold, and calf skinfold are best approximated by a one component log-normal distribution. Children and parents show slightly different patterns in skewness and kurtosis when considered separately, but differences between them do not account for the commingling found in the combined distributions.

ISSN:0001-5652    

DOI:10.1159/000153480

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

The total minutia count (TMC) and fork index (FI), i.e., the proportion of forks in total minutiae, were examined in palm prints of 20 pairs each of monozygotic and dizygotic Japanese twins. No bilateral difference was found in either trait. The mean of the TMC was higher in males than in females, but the FI showed no sex difference. Both traits presented relatively high intraclass correlation coefficients between monozygotic twins, and genetic control of these traits is suggested. However, no correlation was observed between these two traits. A slight correlation was observed between the TMC and the total palmar interdigital ridge count. Some methodological problems concerned with classification criteria were discussed.

ISSN:0001-5652    

DOI:10.1159/000153481

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Frequencies of HLA antigens (A, B, C and DR) were studied in patients with (n = 49) and without (n = 67) a family history of schizophrenia and in controls. Among the patients with a family history of schizophrenia significant increases were found in the A3 and B5 antigens while significant decreases were observed for the A1, A11 and B8 antigens. In a material of schizophrenic siblings the sharing of HLA haplotypes was consistent with normal segregation.

ISSN:0001-5652    

DOI:10.1159/000153482

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

BF- and PI-type determinations have been performed in a population from Sardinia. The corresponding allele frequencies are as follows: BF*S = 0.5783, BF*F = 0.2189, BF*S07 = 0.0046, BF*F1 = 0.1982 and PI*M1= 0.5872, PI*M2 = 0.2041, PI*M3 = 0.0459, Pl*M4 = 0.0940, PI*S = 0.0619, PI*Z = 0.0046, PI*N = 0.0023. Whereas the BF system shows the originality of the Sardinian population with a very high BF*F1 allele frequency, the PI system does not reveal any characteristic features.

ISSN:0001-5652    

DOI:10.1159/000153483

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Blood samples were collected from 162 Kuwaiti Arabs. These samples were typed for the ABO, MNSs, Rh, Kell and Duffy blood group systems, serum protein haptoglobins, the red cell isoenzymes acid phosphatase, phosphoglucomutase (locus 1), adenylate kinase, 6-phosphogluconate dehydrogenase, and the lactate and malate dehydrogenase variants. Comparisons were made with serological findings for other Arab populations in the Arabian peninsula.

ISSN:0001-5652    

DOI:10.1159/000153484

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

A white population from the State of Minnesota of primarily German and Scandinavian heritage was subtyped for α1-antitrypsin variants using isoelectric focusing. The frequencies of the genes PPM1 (0.724), PI*M2 (0.137) and PI*M3 (0.095) were consistent with those for white populations documented in the literature from Northern Europe. Other genes identified in the study were PI*F, PPI, PPP, PPS and PPZ

ISSN:0001-5652    

DOI:10.1159/000153485

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Haptoglobin groups were studied in 100 leukemia patients and controls. Previously reported associations with Hp1-1 and the Hp1 gene by other investigators were not confirmed. In agreement with a previous observation a significant increase of ahaptoglobinemia (Hp0) was found among the leukemia patients.

ISSN:0001-5652    

DOI:10.1159/000153486

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Using gene frequency data often blood group and protein loci (A1A2BO, MNSs, Rh, P, Lu, Fy, Hp, Tf, Hbβ and Gm) the genetic relationships of three tribes, namely, the Toda, Irula, Kurumba in south India and one tribe, namely, the Veddah in Sri Lanka with the Aboriginals in Malay, New Guinea and Australia were studied by genetic distance analysis. The tribes in south India and Sri Lanka are genetically closer to one another than to the Aboriginals in southeast Asia and Oceania. Despite their morphological similarity there is no genetic evidence to suggest that the Indian tribes and Australian Aboriginals are biologically related

ISSN:0001-5652    

DOI:10.1159/000153487

出版商:S. Karger AG    

年代:1984

数据来源: Karger

摘要:

Statistical procedures based on a Poisson hypothesis for surveying serial occurrences of incidence were developed. Three methods, the z-test, the cusum technique and the sequential test were applied in a study of a nationwide screening system on newborns for hereditary metabolic disorders in Japan. It was found that the statistical tests well detected human errors involved in data processing.

ISSN:0001-5652    

DOI:10.1159/000153488

出版商:S. Karger AG    

年代:1984

数据来源: Karger