摘要:

AbstractThe use of zeolites as selective catalysts and adsorbents in organic syntheses is a field of growing importance. A brief discussion of the structure, modification and catalytic properties of zeolites relevant to the topic is presented. Some non‐ and semi‐catalytic applications of zeolites in fine‐chemical preparation are mentioned and examples are given of zeolite catalysis in oil refining and petrochemicals production. Further examples of the use of zeolites as catalysts in organic reactions are chosen from the fields of isomerization, aromatic substitution, oxidation, cyclization and heterocyclic ring form

ISSN:0165-0513    

DOI:10.1002/recl.19891080902

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

摘要:

AbstractThe reaction of both the novel mixed trinuclear organo‐organic copper(I) species [Cu3(C6H2Me3‐2,4,6)(μ‐O2CC6H5)2] (1) and [Cu(μ‐O2CC6H5)]4(2a) with quinoline in toluene or diethyl ether yields the dimeric 1:2 copper/quinoline complex [Cu(μ‐O2CC6H5)(NC9H7)2]2(3a). The reactions of methyl‐substituted copper(I) benzoates, [Cu(μ‐O2CC6H4Me‐x)]4(x= 2,2b;x= 3,2c;x= 4,2d), with quinoline in toluene or diethyl ether, however, afford the 1:1 copper/quinoline complexes [Cu(μ‐O2CC6H4Me‐x)(NC9H7)]2(x= 2,4b;x= 3,4c;x= 4,4d).The structure of complex4b, determined by a single‐crystal X‐ray diffraction study, shows a dicopper(I) unit doubly bridged by two benzoato units [Cul…Cul* = 2.667(1) Å]. At each copper site, the CuO bonds to the bridging benzoato groups differ considerably [Cul‐Ol = 1.923(5) Å; Cul‐O2* = 2.134(5) Å]. Coordination of a quinoline at each copper site [Cul‐Nl = 1.952(5) R] produces a distorted trigonal arrangement.Crystallization of the 1:2 copper‐quinoline complex3aled to formation of crystals of the dimeric 1:1 copper/quinoline complex [Cu(μ‐O2CC6H5)(NC9H7)]2,4a. The structure of4ais similar to that of4b[Cul…Cul* = 2.638(2) Å Cul‐Ol = 1.945(6) Å Cul‐O2* = 2.107(6) Å Cul‐Nl = 1.939(7) Å]. Since complexes3and4can be expected to be similar to the intermediates formed in the copper‐quinoline decarboxylation reaction, the reactivity of3and4at elevated temperatures in non‐coordinating solvents has been studied. It was found that the decarboxylation reaction requires more than one equivalent of quinoline per copper atom. An improved mechanism is presented for the copper‐quinoline decarboxylation r

ISSN:0165-0513    

DOI:10.1002/recl.19891080903

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

摘要:

Abstract(4‐2H)‐, (5‐2H)‐, (6‐2H)‐, (7‐2H)‐, (4‐13C)‐ and (5‐13C)‐1H‐indole and the corresponding six L‐tryptophans [(4‐2H)‐, (5‐2H)‐, (6‐2H)‐, (7‐2H)‐, (4‐13C)‐ and (5‐13C)‐] have been synthesized from simple labelled starting materials via a single reaction scheme. The L‐tryptophans were prepared from the indoles via a quantitative one‐step biosynthetic conversion. A scheme leading to the synthesis of three other indoles, mono‐13C‐enriched in the six‐membered ring, has been developed and optimized. Indole and L‐tryptophan,13C‐ or2H‐enriched at the positions 4 or 5, have been synthesized with 99% isotope incorporation without scrambling. (6‐2H)‐1H‐Indole and ‐tryptophan have been synthesized with 95% deuterium incorporation and (7‐2H)‐1H‐indole and ‐tryptophan with 96%. The reactions have been carried out on a gram scale and, in the case of the 4‐13C

ISSN:0165-0513    

DOI:10.1002/recl.19891080904

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

摘要:

AbstractThe use of diethoxytriphenylphosphorane in the preparation of benzyl (S)‐2‐aziridinecarboxylate is illustrated. The latter compound has been coupled with Z‐Ala‐OH and the aziridine dipeptide thus obtained ring‐opened via C‐3‐N‐1 cleavage with benzyl alcohol and ethanethiol to afford Z‐Ala‐Ser(Bzl)‐OBzl and Z‐Ala‐C

ISSN:0165-0513    

DOI:10.1002/recl.19891080905

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

摘要:

AbstractA convenient one step synthesis of tetrasubstituted benzo(ij)cycl[3.3.2]azines is performed through the reactions between disubstituted alkynes and cyclopalladated 8‐methylquinoline specie

ISSN:0165-0513    

DOI:10.1002/recl.19891080906

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

摘要:

AbstractThe previously reported syntheses of HN(CH2CH2AsMe2)2are found to be irreproducible. Two by‐products, the compound ClCH2CH2N(H)CH2CH2AsMe2and the salt {H2N(CH2CH2AsMe2)2}+I−, have been identif

ISSN:0165-0513    

DOI:10.1002/recl.19891080907

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19891080908

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19891080910

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19891080901

出版商:WILEY‐VCH Verlag    

年代:1989

数据来源: WILEY