摘要:

AbstractThe systematic synthesis of the simplified reserpine skeleton to the stage at which reserpine like activity was observed, is described.

ISSN:0165-0513    

DOI:10.1002/recl.19610800202

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractUsing benzoic acid‐1‐14C the position of the hydroxyl group formed in the oxidation of benzoic acid to phenol and carbon dioxide is definitively identified as ortho in relation to the original carboxyl gr

ISSN:0165-0513    

DOI:10.1002/recl.19610800203

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractThe benzenesulphonates of xylenols undergo isomerisation when heated with anhydrous aluminium chloride, giving hydroxy‐sulphones, the structures of which have been establishe

ISSN:0165-0513    

DOI:10.1002/recl.19610800204

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractBy condensing the potassium salt of isatinic acid ‐ (o‐aminophenyl)‐glyoxylic acid ‐ with urea,N‐substituted ureas and ethyl carbamate, 2‐hydroxyquinazoline‐4‐carboxylic acid was obtained, in excellent yield. In a similar condensation with guanidine, potassium isatinate reacted quantitatively to give 2‐aminoquinazoline‐4‐carboxylic acid. Various derivatives were obtained from these new acids by methylation and deca

ISSN:0165-0513    

DOI:10.1002/recl.19610800205

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractThe synthesis of four 2,4‐dichloro‐6‐(p substituted phenyl) 1,3,5‐triazines is described. The U.V. spectra of these compounds and those of the derivatives mentioned in the preceding papers1,2,3are dealt with and di

ISSN:0165-0513    

DOI:10.1002/recl.19610800206

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractElectron spin resonance was measured at room temperature in a mixture of TiCl4and Al(C2H5)2Cl in heptane. No resonance could be demonstrated in the precipitate. At room temperature the concentration of unpaired electrons reaches its maximum value in approx. 10 minutes. At an Al/Ti ratio less than one the concentration of unpaired electrons remains for some hours at a constant value of about 4.6 × 10−3times the initial concentration of aluminium compound, a value which is only slightly dependent on the initial titanium concentration.At higher temperatures or at an Al/Ti ratio greater than one the number of unpaired electrons also reaches a maximum, but decreases afterwards.The concentration of unpaired electrons appeared to be highly governed both by the TiCl3precipitate formed and by other substances, such as water, alcohol, carbon tetrabromide and oxyg

ISSN:0165-0513    

DOI:10.1002/recl.19610800207

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractAmong the alkyl substituted 3‐phenyl‐4‐hydroxycoumarins, synthesized to investigate the relationship between chemical structure and biological activity in this class of compounds2, eleven possess one or moreorthosubstituents.As the steric effects oforthosubstitution can manifest themselves in the polarographic behaviour, the half wave potentials of these compounds were measured and attempts were made to find relationships between the values obtained and to determine the steric effect in each case. In addition, an equation was derived for the first reduction wave in the polarogram and a reaction mechanism for this polarographic reduction is sugg

ISSN:0165-0513    

DOI:10.1002/recl.19610800208

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractThe synthesis is described of nor‐vitamin B6(nor‐pyridoxol) by a selective demethylation of a suitable vitamin B6precursor. The demethylation is accomplished in a three step process following the sequence CH3→ CHO → COOH → H, in which SeO2appears to be a particularly selective oxidant for the first step. The nor‐vitamin B6proves to be biologically inactive on the growth ofSaccharomyces carlsbergensisas well as in growth‐tests on ratsG. PolandK. J. Klein Obbink,ibid.80

ISSN:0165-0513    

DOI:10.1002/recl.19610800209

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractNor‐vitamin B6is inactive as a substitute for vitamin B6in growth tests withSaccharomyces carlsbergensisand does not inhibit the effect of vitamin B6. It has little, if any, effect on the growth of vitamin B6‐deficient r

ISSN:0165-0513    

DOI:10.1002/recl.19610800210

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY

摘要:

AbstractThe synthesis of 4,5‐dihydroxymethyl‐6‐hydroxy‐2‐methylpyridine, an isomer of vitamin B6, is described.This isomer is biologically inactive on the growth ofSaccharomyces carls

ISSN:0165-0513    

DOI:10.1002/recl.19610800211

出版商:WILEY‐VCH Verlag    

年代:1961

数据来源: WILEY