摘要:

AbstractThe syntheses of several 7‐substituted imidazo[4,5‐b]pyridines (6‐substituted 1‐deazapurines) and of 7‐substitutedvic‐triazolo[4,5‐b]pyridines (6‐substituted 1‐deaza‐8‐azapurines) are described. A few 6‐substituted 3‐deazapurines and 3‐deaza‐8‐azapurines were also synthesized.Finally the results of an investigation on the effect of the deazapurines upon the gr

ISSN:0165-0513    

DOI:10.1002/recl.19710901102

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe direct condensation of 7‐chloro‐vic‐triazolo[4,5‐b]pyridine (I) with 2,3,5‐tri‐O‐benzoylribofuranosyl chloride (III) in nitromethane containing potassium cyanide, afforded two isomeric blocked nucleosides. Debenzoylation of these products gave the ribosides 7‐chloro‐3‐β‐D‐ribofuranosyl‐vic‐triazolo[4,5‐b]‐pyridine (VI) and its 2‐ribosylated isomer VII. From the reaction of the chloromercuri derivative ofvic‐triazolo[4.5‐b]pyridine (X) with III in boiling toluene, followed by subsequent debenzoylation of the reaction products, three isomeric ribosides were obtained: 1‐, 2‐ and 3‐β‐D‐ribofuranosyl‐vic‐triazolo[4,5‐b]‐pyridine (XVI, XV and XIV). The position of attachment of the sugar moiety to thevic‐triazolo[4.5‐b]pyridine ring system and the assignment of anomeric configuration for all nucleosides reported, are discussed. A number of 7‐substituted 3‐β‐D‐ribofuranosyl‐vic‐triazolo[4,5‐b]pyridines ‐ including 1‐deaz

ISSN:0165-0513    

DOI:10.1002/recl.19710901103

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractMolecular nitrogen has been bonded on vanadium trichloride, after reduction with lithium naphthalide. During these reduction and fixation reactions several ESR‐signals appeared. By measurements of signal intensities in the presence and absence of N2it was shown that these signals did not correspond with a vanadium‐nitrogen complex. They do indicate, however, the degree of reduction of the system and therefore provide information on the state of reduction of the complex (not ESR‐active in itself) that bin

ISSN:0165-0513    

DOI:10.1002/recl.19710901104

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

Abstract4‐Ethyl‐ and 4‐isobutyl‐2‐methyl‐2‐buten‐4‐olide have been prepared by reaction of 2‐butanone and 4‐methyl‐2‐pentanone with sodium pyruvate, followed by reduction of the 2‐hydroxy‐2‐methyl‐4‐oxoalkanoic acids obtained, and lactonization to 4‐alkyl‐2‐hydroxy‐2‐methyl‐4‐butanolides. Treatment with triphenylphosphine in carbon tetrachloride caused extensive desaturation.The stereochemistry of the cyclic hydroxy and chloro intermediates was determined from the

ISSN:0165-0513    

DOI:10.1002/recl.19710901105

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractAn investigation was carried out on the specific tritium labelling of naphthalene and 1,2,3,4‐tetrahydronaphthalene (tetralin), using tritium gas as one of the reactants. It was demonstrated that specific labelling of naphthalene with deuterium or tritium was possible by catalytic hydrogenolysis of phenyltetrazolyl ethers as well as by catalytic dehalogenation of halogeno compounds, but dehalogenation gave better chemical and isotopic yields. Specific labelling of tetralin was attained only by dehalogenation with a palladium on carbon catalyst in the presence of potassium hydroxid

ISSN:0165-0513    

DOI:10.1002/recl.19710901106

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe novel heterocyclic compoundss‐triazolo[5,1‐a]isoquinoline, IIa, ands‐triazolo [3,2‐c]pyridine, IV, together with a few derivatives have been synthesized by isomerisation of the corresponding [3,4‐a] isomers by base in ethylene glycol/water. The spectral properties are

ISSN:0165-0513    

DOI:10.1002/recl.19710901107

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe activity of zeolite‐based catalysts containing protons was investigated in the hydrogen‐deuterium exchange reaction of methane with deuterium oxide at temperatures above 600

ISSN:0165-0513    

DOI:10.1002/recl.19710901108

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractEvidence is presented that the conversion of 4‐bromo‐6‐phenylpyrimidine into 4‐amino‐6‐phenylpyrimidine by treatment with potassium amide in liquid ammonia at ‐75° occurs to the extent of about 80% according to a mechanism involving an open‐ch

ISSN:0165-0513    

DOI:10.1002/recl.19710901109

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractPyrimidine is converted by heating with aqueous methylamine or ammonia at 190° into 5‐ethyl‐2‐methylpyridine (

ISSN:0165-0513    

DOI:10.1002/recl.19710901110

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractA number of compounds of formula M(NnBuIz)n(anion)2are described, the metal ions being Mn, Fe, Co, Ni, Cu, Zn and Cd and the anions Cl−, Br−, I−and NCS−;NnBuIz stands forN‐n‐butylimidazole and n = 1–6.The compounds are prepared from the corresponding metal salts and the ligand in ethanol, and are characterized by chemical analyses and physical measurements.The ligandNnBuIz is shown to coordinate with metal ionsviathe lone pair electrons of the pyridine‐nitrogen of the five‐membered ring. Metal(II) ions are found to be (pseudo)‐octahedral six coordinate for all compounds having n = 6 andn= 4, and for the Cu(II) compounds withn= 1 and 2. The remaining compounds withn= 2 have tetrahedrally coo

ISSN:0165-0513    

DOI:10.1002/recl.19710901111

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY