摘要:

Abstract2‐X‐1,7‐Naphthyridines (X = Br, Cl) give a variety of products on treatment with potassium amide, namely 2‐amino‐1,7‐naphthyridine [formed by an SN(AE) process], 4‐amino‐ and 8‐amino‐1,7‐naphthyridine (obtained by atele‐amination[5N(AE)t]) and a ring transformed product, 2‐methyl‐4‐amino‐1,3,7‐triazanaphthalene. By1H‐NMR spectroscopy of a solution of 2‐chloro‐1,7‐naphthyridine and its 8‐deutero‐ and 6,8‐dideutero derivatives in KNH2/NH3good evidence has been obtained that at −40° 2‐chloro‐1,7‐naphthyridine is completely converted into a mixture of three 1 : 1 adducts formed by addition of the amide ion at C(8), C(6) and C(4). 8‐X‐1,7‐Naphthyridines (X = Cl, Br) give as sole reaction products 8‐amino‐1,7‐naphthyridine [5N(AE)] and 2‐amino‐1,7‐naphthyridine [5N(AE)t]. By1H‐NMR spectroscopy strong evidence has been obtained that in 8‐X‐1,7‐naphthyridines the adduct for

ISSN:0165-0513    

DOI:10.1002/recl.19770960602

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19770960603

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractIn the dye‐sensitized photo‐oxidation of hexamethylbenzene two molecules of singlet oxygen are rapidly taken up: one of the oxygenation steps involved is an ene‐type reaction, and the other a [4 + 2]‐cycloaddition. The resulting endoperoxy hydroperoxide2can be reduced selectively to the corresponding endoperoxy alcohol3and by further reduction to the triol4. X‐ray analysis shows the hydroperoxy group and the OO bridge in2to be on different sides of the cycl

ISSN:0165-0513    

DOI:10.1002/recl.19770960604

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19770960605

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractVarious nucleophiles (sodium methoxide, hydride ion, thiolates and carbanions derived from organomagnesium compounds and ketones) react with 3‐[bis(methylthio)methylene]‐2‐thiolanones giving a rearrangement. The mechanism of the proposed rearrangement has been investigated. The reaction of enolate ions with thiolanones produces new β‐d

ISSN:0165-0513    

DOI:10.1002/recl.19770960606

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractHalogenation of vinylcopper(I) compounds [RR′CCHCu(Br or R)]MgX, prepared stereospecifically bycis‐addition of [RCuBr]MgX or [R2Cu]MgX to 1‐alkynes R′‐C≡CH in tetrahydrofuran, with one of the halogenating reagentsN‐chlorosuccinimide,N‐bromosuccinimide, BrCN, ICN or I2, leads in high yields to the corresponding 1‐halogeno‐1‐alkenes RR′CCHX (X = Cl, Br or I). The introduction of the halogen atom occurs with retention of configura

ISSN:0165-0513    

DOI:10.1002/recl.19770960607

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractOn the basis oftrans‐2‐hexene‐1,6‐diol andtrans‐2‐octenol, both obtained by trans reduction of their acetylenic precursors with sodium in liquid ammonia,trans‐5‐eicosene‐8,1 1,14‐triynoic acid andtrans‐ 14‐eicosene‐5,8,11‐triynoic acid were built up by classical methods. Partial hydrogenation and esterification afforded the desired eicosatetraenoates. In addition, reduction of previously describedtrans‐2‐eicosene‐5,8,11,14‐tetraynoic acid gavet‐2,c

ISSN:0165-0513    

DOI:10.1002/recl.19770960608

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractBenzene, chlorobenzene or benzonitrile, in the presence of a little C2Cl6or formaldehyde, reacts with HCN at ∼ 480° (30 s) to give the (mono)cyano derivatives. Features, especially isomer distributions for this cyanation closely resemble those for gas‐phase chlorination. By analogy, therefore, a free radical mechanism is advanced involving endothermal hydrogen abstraction by Cl•and/or H•to give aryl radicals, which in turn attack HCN at carbon, displacing hydrogen. Pyridine leads to cyanopyridines (89 % 2‐, 6 % 3‐, 5 % 4‐isomer), the 2‐position being ∼ 3 times as reactive as benzene hydrogens. This supports our view that differences in CH bond strength play a major part, as it is known that 2‐pyridyl is stabilized relative to its 3‐ and 4‐analogues. ICN was found not to be a su

ISSN:0165-0513    

DOI:10.1002/recl.19770960609

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractReacting the title compound with lithium dimethylamide and subsequent addition of methyl iodide yieldsE‐β‐(dimethylamino)‐o‐(methylthio

ISSN:0165-0513    

DOI:10.1002/recl.19770960610

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19770960611

出版商:WILEY‐VCH Verlag    

年代:1977

数据来源: WILEY