摘要:

AbstractThe chemical preparation is described of linear polyalkene ureas from aliphatic α,ω‐diamines and carbon oxysulphide. Using chemical and physical methods, the mechanism of the poly‐condensation reaction is studied and a satisfactory picture of the structure and of the mode of formation is obtained.After melt‐spinning the products can be cold‐stretched to form strong and flexi

ISSN:0165-0513    

DOI:10.1002/recl.19550741102

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractFrom the work ofR. Kuhnet al. it appeared that brominated derivatives of salicil have a high anti‐bacterial activity in vitro, but that in vivo they show only little activity as a result of serum‐binding. Base‐substituted phenols are usually bound by serum to a smaller extent. Therefore, an amino‐substituted bromo‐salicil was synthesized. A water soluble derivative of this compound was also

ISSN:0165-0513    

DOI:10.1002/recl.19550741103

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractThe fatty acid oxidation of normal liver mitochondria was found to be inhibited after the addition of mitochondria from many transplanted and spontaneous mouse tumors. This inhibitory effect was not an exclusive property of tumor mitochondria, it was also exhibited by rat brain mitochondria and by liver mitochondria pre‐incubated at 37° C in the absence of substrates. Addition of fluoride to the combined system of tumor and liver mitochondria counteracted the inhibitory effect of the former on the fatty add oxidation of the latter. These results, obtained with theWarburgtechnique, were confirmed and substantiated by experiments with radioactive substrates.The conditions governing the inhibitory effect were studied, and it was found that those conditions which favoured the latency of the mitochondrial adenosine triphosphate‐splitting activities resulted in a disappearance of the inhibitory effect in many cases. It was concluded for the present that, by the splitting of adenosine triphosphate, the active adenosine triphosphatase of the tumor mitochondria prevented the ATP‐dependent formation of the acyl‐co‐enzyme A bond, which is a prerequisite for the fatty acid oxidation of the liver mitochondria.The tumors studied could be listed in the order of an increasing tendency to show the inhibitory effect as a result of different treatment during preparation of the mitochondria.During this investigation it was demonstrated for the first time that mitochondria from various transplanted tumors, if isolated in isotonic sucrose‐containing versene, are capable of oxidizing octanoate.The osmotic behaviour of liver and tumor mitochondria was also studied, and some direct measurements of the inorganic phosphate liberated from ATP by the action of these mitochondr

ISSN:0165-0513    

DOI:10.1002/recl.19550741104

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractIt is demonstrated that direct oxidation of L‐gulono‐γ‐lactone by Fenton's reagent gives rise to a reducing substance, which, according to all the reactions used, is identical with L‐ascor

ISSN:0165-0513    

DOI:10.1002/recl.19550741105

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19550741106

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractNylon 6 type polyamide equilibrium products prepared from ε‐caprolactam and water in closed systems at temperatures of 222 and 254° C have been investigated. Unconverted caprolactam, higher membered cyclic compounds, chain fractions and end‐groups (−NH2and −COOH) were determined quantitatively. Percentages of caprolactam and higher rings increase with increasing temperature and/or increasing water content (corresponding to decreasing DP) of equilibrium products. Number‐average DP of chain fractions varied from ∼ 100 → 10 in the range investigated. The results have been evaluated in terms of equilibrium constants on the basis of plausible theoretical considerations including the Flory‐Schulz distribution of chain lengths.The equilibrium constant of the polycondensation reaction has been found to decrease with decreasing DP of products. This behaviour is in accordance with similar results obtained for different polyamide equilibrium products. Possible explanations are discussed. A comparison with some data available from the liter

ISSN:0165-0513    

DOI:10.1002/recl.19550741107

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractThe synthesis is reported of N.N′‐alkylated α,α′‐, β,β′ and γ,γ′‐bipyridylium diiodides (Type I), and of N,N′‐alkylated α, α′‐, β,β′‐ and γ,γ′‐bipiperidylium diiodides (Type II) listed in Table I. It was found thatwhen the bipyridyls were hydrogenated in absolute methanolic or ethanolic solution in the presence of a nickel catalyst not only reduction of the pyridine rings took place, but also N‐alkylation by the alcohols. This nickel‐catalyzed “hydrogenation‐alkylation” gave satisfactory yields.In table II some N‐alkylated di‐(α‐pyridylium) and di‐(α‐piperidylium)‐methane and ethane diiodides of the Types III and IV are summarized.Syntheses are described of di‐(α‐pyridyl)‐methane and 1,2‐di‐(α‐pyridyl)‐ethane, which compounds were needed as intermediates for the preparation of III and IV.The compounds listed in the Tables I and II were

ISSN:0165-0513    

DOI:10.1002/recl.19550741108

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractThe chloroacetones CH2Cl. CO. CH3, CHCl2CO. CH3, CH2Cl. CO. CH2CL CHCl2CO. CH2Cl, and CHCl2CO. CHCl2have been prepared. Their Raman spectra as well as those of several other chloroketones and chloroacid chlorides have been determined. A comparative study of these spectra reveals that the specific bending frequencies for the groups CH3and CH2Cl, as deduced for the chloropropanes, show a characteristic shift to lower values if these groups are directly attached to the carbonyl group; the “CCl3frequency” is shifted to a higher value. An intense Raman line at 350 cm−1, which has been found in the spectra of several chloropropanes and chloropropenes containing a CHCl2group, is particularly strong and characteristic in carbonyl compounds possessing the configuration CHCl2CO. ‐ or CHCl2CHCl. CO.‐. The carbonyl group frequency shows highly different values for groups of compounds such as saturated ketones (1730‐1760 cm−1), unsaturated ketones (1710‐1720 cm−1), and acid chlorides (1780‐1820 cm−1).v(CO) gradually Increases with an increasing substitution of chlorine for hydrogen in the molecule of saturated ketones. In unsaturated ketones, in which C  O and CC are conjugated,v(CO) andv(CC) are lowered

ISSN:0165-0513    

DOI:10.1002/recl.19550741109

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractFor an investigation into the physiological activity of certain compounds we required I as starting material. We prepared it by the method described below.

ISSN:0165-0513    

DOI:10.1002/recl.19550741110

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY

摘要:

AbstractThe Raman spectra of a number of chloroethers and chloroalcohols are communicated, several of which contain the grouping CCl3CHCl. CH2‐ or CHCl2CHCl. CH2‐. A comparative study of these spectra reveals that specific group frequencies deduced for the chloropropanes retain their values in the ethers and alcohols, and that additional characteristic frequencies may be distinguished for the configurations ‐OCH3and ‐CH2O‐.For a number of the compounds studied, structural formulae which had not yet been established with certainty could be confirmed by means of Raman analysis,i.e.on account of specific group frequencies and spectral analogies observed.As a final conclusion from our Raman spectroscopic investigations on aliphatic chlorine compounds the “specific group frequencies” deduced a

ISSN:0165-0513    

DOI:10.1002/recl.19550741111

出版商:WILEY‐VCH Verlag    

年代:1955

数据来源: WILEY