ISSN:0165-0513    

DOI:10.1002/recl.19700890902

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

Abstract1‐Tosylalkyl isocyanates,p‐CH3C6H4SO2CHRNCO (II), have been prepared in good yields from the reaction ofS‐ethylN‐(1‐tosylalkyl)thiocarbamates (I) and chlorine in a heterogeneous mixture of dichloromethane and aqueous sodium hydrogen carbonate. The reaction probably involves the intermediate formation of the previously unreportedN‐(1‐tosylalkyl)carbamoyl chlorides,p‐CH3C6H4SO2CHRNR′COCl (IV), which may be isolated in high yield under anhydrous reaction conditions. In mildly alkaline solutions, these carbamoyl chlorides (R′  H) are smoothly converted into the 1‐tosylalkyl isocyanates. EthanesulfonylN‐methyl‐N‐(tosylmethyl)formamide (V), obtained by oxidation ofS‐ethylN‐methyl‐N‐(tosylmethyl)thiocarbamate,p‐CH3C6H4SO2CH2N(CH3)C(O)SC2H5, with hydrogen peroxide in acetic acid, was treated with chlorine to give tosyl chloride and ethanesulfonyl chloride. α‐Oxosulfones,p‐CH3C6H4SO2CH2N(CH3)C(O)SO2C2H5, are therefore unlikely intermediates in the formation ofN‐(1‐tosylalkyl)carbamoyl chlorides.The reaction ofS‐ethylN‐(1‐tosylalkyl)thiocarbamates (I) with bromine in CH2Cl2/NaHCO3‐H2O in the presence of methanol gives methylN‐(1‐tosylalkyl) carbamates, a result which can be best i

ISSN:0165-0513    

DOI:10.1002/recl.19700890903

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractThe photoreactions of some methoxynitro‐, dimethoxynitro‐ and dinitronaph‐thalenes in alkaline medium are described. From the reactions observed (substitution of OCH3or NO2by OH) it appears that in the excited state of the naphthalene derivatives a nitro group in the one ring exerts a definite activating influence also on positions in the other ring. In these reactions specific “meta‐activation” was

ISSN:0165-0513    

DOI:10.1002/recl.19700890904

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractThis paper presents the repeat periods of some thirty cyclohexane derivatives, in their respective thiourea adducts as determined by X‐ray diffraction and elemental analysis. In general,trans‐1,4‐substituted cyclohexanes are found to occupy longer sections of the thiourea channel than the correspondingcis‐isomers. In some thiourea adducts the thiourea lattice is deformed as shown by X

ISSN:0165-0513    

DOI:10.1002/recl.19700890905

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractAn X‐ray diffraction study of the reduction product of the head‐to‐head photodimer of isophorone has shown that the six‐membered rings are inantiposition relative to the four‐memb

ISSN:0165-0513    

DOI:10.1002/recl.19700890906

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractThe reaction of the dienamine (1) from 8a‐methyl‐1,6‐dioxo‐1,2,3,4,6,7, 8,8a‐octahydronaphthalene, with arenediazonium salts, has been investigated. Depending upon the solvent, β‐ as well as δ‐substituted products are obtained. A rationalization for this substitution pattern is proposed. The β‐substituted product, obtained upon reaction of 1 withm‐methoxybenzenediazonium fluoroborate, has been converted into 6,7‐diaza‐D‐homoequilenin methyl ethe

ISSN:0165-0513    

DOI:10.1002/recl.19700890907

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

Abstract6,7‐Diazasteroidal systems(4a,b)have been prepared by the reaction of dienamines2a,bwithm‐methoxybenzenediazonium fluoroborate in one practical step. The reaction also yields hydrazones5a,band6a,b, as by‐products, which have been converted into certain quinoline(14a, b)and indole(20)derivatives, respectively. Diazasteroid4awas transformed to 6,7‐diaza‐11‐oxoequilenin‐3‐m

ISSN:0165-0513    

DOI:10.1002/recl.19700890908

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractReaction of conjugated enamines with α‐bromoketones leads to the formation of substituted furans in one practical step. The reaction has been applied to the synthesis of steroido[3,4‐b]fu

ISSN:0165-0513    

DOI:10.1002/recl.19700890909

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

Abstract17‐Oxo steroids in a Reformatsky reaction with the ethyl ester of γ‐bromo‐β‐ethoxycrotonic acid gave rise to isomeric pairs of 17‐spirolactones. The spirolactone moiety of these compounds has been modified and related to that of known sp

ISSN:0165-0513    

DOI:10.1002/recl.19700890910

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY

摘要:

AbstractThe conformational equilibrium in six 2‐alkylthiotetrahydropyrans is studied by means of dipole moment measurements and NMR spectroscopy. In these compounds the anomeric alkylthio group has, in general, a slight preference for the axial position. From the occurrence of a linear relationship between the squares of the dipole moments and vicinal coupling constants the conclusion follows that only one axial and one or two equatorial conformers are present in the equilibrium. A comparison is made with the conformation of the anomeric alkoxy grou

ISSN:0165-0513    

DOI:10.1002/recl.19700890911

出版商:WILEY‐VCH Verlag    

年代:1970

数据来源: WILEY