摘要:

AbstractThe synthesis of 4‐amino‐5‐p‐chlorophenylpyrimidine by the reaction of tris‐formylaminomethane withp‐chlorobenzyl cyanide is described and, from this, by replacement reactions, five new pyrimidine compounds a

ISSN:0165-0513    

DOI:10.1002/recl.19710900602

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe reaction between diphenylketene and ethoxyacetylene followed by alkaline hydrolysis, gives a crystalline solid with the formula C16H12O2. A structure determination by X‐ray diffraction shows that this compound is 3‐hydroxy‐9‐phenyl‐1,9‐dihydroazulen‐1‐one. The molecular skeleton consists of a planar five‐membered ring fused to a boat shaped seven‐membered ring. In the crystal there are chains of molecules along the monoclinicb‐axis; successive molecules are linked by C‐OH ··· OC hydrogen bonds with a le

ISSN:0165-0513    

DOI:10.1002/recl.19710900603

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractOn treatment of 5‐halogeno‐1‐methylimidazole with lithium piperidide in piperidine, an addition‐elimination reaction giving 1‐methyl‐5‐piperidino‐imidazole, transhalogenation giving 4‐halogeno‐1‐methylimidazole and ametasubstitution yielding the 1‐methyl‐2‐piperidino‐imidazole, were observed. No indication for the occurrence of a 4,5‐didehydro

ISSN:0165-0513    

DOI:10.1002/recl.19710900604

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractConversion of β‐alkoxy‐ and β‐alkylthio‐β‐chloroacryloyl chlorides R′Y‐CCICR‐COCl (1. RH or alkyl, R′ = alkyl and YO or S) with amines yields the expected carboxamides R′Y‐CClCR‐CO‐NHR″. Phenylhydrazine reacts with β‐alkoxy‐β‐chloroacryloyl chlorides to give a mixture of 3‐alkoxy‐ 1‐phenyl‐2‐pyrazolin

ISSN:0165-0513    

DOI:10.1002/recl.19710900605

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe behaviour of photo‐excited 4‐nitroanisole toward nucleophilic reagents in aqueous solution is intriguing and only partially understood2,3,4. With hydroxide it yields 4‐nitrophenoxide and 4‐methoxy‐phenoxide5,6. On irradiation with alkylamines it givesN‐alkyl‐4‐nitro‐anilines7. A considerable amount of nitrite ion has been detected in the reaction with amines8, but it has as yet not been possible to isolate the corresponding substitution product.Letsingerand his coworkers5demonstrated that 4‐nitroanisole on photoreaction with pyridine affordsN‐(4‐methoxyphenyl)pyridinium nitrite. Interestingly, 4‐nitroanisole in its excited state undergoes substitution by cyanide ion exclusively at the position meta with respect to the nitro group, yielding 2‐cyano‐4‐nitroanisole9. This reaction is sensitive to oxygen: in solutions well purged with nitrogen, yields of 2‐cyano‐4‐nitroanisole are much l

ISSN:0165-0513    

DOI:10.1002/recl.19710900606

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractThe oxidation of dithiocarboxylic esters with peracids is described. Methyl dithio‐l‐naphthoate (I) produces thetrans‐ andcis‐(methylthio)sulfines I la and IIb. Thetrans‐isomerIIa gives on oxidation thetrans‐(methylsulfinyl)sulfine IIIa, which is then converted to thetrans‐(methylsulfonyl)sulfine IVa by further treatment with a peracid (Scheme I). Similarly phenyl dithiobenzoate (V) givestrans‐ andcis‐phenyl(phenylthio)sulfine (VIa and VIb). Each of these isomers was subjected to further oxidation giving thetrans‐ andcis‐phenyl(phenylsulfinyl) sulfines VIIa and VIIb, and thetrans‐ andcis‐phenyl(phenylsulfonyl)sulfines, VIIIa and VIIIb (Scheme II). Similarly, phenyl 2,4,6‐trimethyldithiobenzoate (IX) is oxidized to the correspondingtrans‐ andcis‐mesityl(phenylthio)‐, mesityl (phenylsulfinyl) and mesityl(phenylsulfonyl)sulfines, Xa,b, XIa,b and XIIa,b, respectively. (Scheme III).The spectra, particularly the PMR spectra, are discussed in conjunction with the structural assignment of the sulfines. The deshielding effect of the>CSO group and also intramolecular shielding effects are invoked. Interestingly, theortho‐methyl groups in both mesityl(phenylsulfinyl)sulfines (XIa,b) are magnetically non‐equivalent. This results from the asymmetric sulfoxide function in these sulfines which makes the t

ISSN:0165-0513    

DOI:10.1002/recl.19710900607

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractRecently, it has been shown1that the association constants of 1,3,5‐trinitrobenzene with various hydrocarbons containing two equivalent, symmetrically disposed, phenyl rings have twice the values of the complexes of the corresponding “half” molecules (Table I). It is generally considered that these interactions are electron donor‐acceptor (charge‐transfer) complexes, in which the donor site is the aromatic ring2. The values of the association constants may be accounted for if each site in the bis‐phenyl compounds behaves independently of the remaining sites so that such molecules simply provide, on a statistical basis, twice the number of sites per molecule compared with the corresponding “half” molecules. It is recognised that such behaviour is remarkable in the cases of tolan andtrans‐stilbene in which there is conjugation between the two phenyl rings. The complexing behaviour of a series of bis‐anilines h

ISSN:0165-0513    

DOI:10.1002/recl.19710900608

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractPhenol OH stretching frequency shifts, Δν, have been measured for the hydrogen‐bonded complexes between phenol and a series ofN,N‐disubstituted sulfinamides and sulfonamides. The magnitudes of these Δν values indicate that the SO group is the acceptor site. The acceptor properties are interpreted chiefly in terms of inductive effects complemented by resonance effects involving π‐bonding between the sulfur and the nitrogen atom without significant alteration of the sulfur‐oxy

ISSN:0165-0513    

DOI:10.1002/recl.19710900609

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractBenzenediazocyanides, a class of highly fungicidal compounds, were investigated with special reference to their interaction with fungal cell thiols.Spores ofFusarium culmorumtook up readily diazocyanides with fungicidal properties. The 4‐hydroxy derivative was not taken up in neutral medium. Both uptake andin vitroactivity of this compound were strongly enhanced by lowering of the pH, indicating that mainly the non‐ionised form (OH) was taken up. Rate of uptake of uncharged fungicidal diazocyanides was found roughly to parallel their rate of reaction with cysteine. Furthermore, a close similarity of the spectra of conversion products released by spores and of cysteine reaction products was observed. Benzenediazocyanides with electron‐donating substituents are supposed to undergo mainly addition of thiols to the nitrile group, whereas compounds with electron‐withdrawing substituents seem to undergo both addition to the nitrile group and reduction of the azo group. Consequently, it is concluded that benzenediazocyanides, like many other classes of fungicidal compounds, react with sulfhydryl groups within the fungal cell in a non‐specific way.In solution benzenediazocyanides, like other classes of azo compounds, are known to be decomposed by light. The photodecomposition products, identified as the corresponding benzenediazonium ions and phenols, turned out to be considerably less fungitoxicin vitrothan the parent compounds. Benzenediazocyanides with strongly electron‐donating phenyl substituents were found to be relatively stab

ISSN:0165-0513    

DOI:10.1002/recl.19710900610

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY

摘要:

AbstractFusion of 7‐chloroimidazo[4,5‐b]pyridine (IV, 6‐chloro‐1‐deazapurine) with tetra‐O‐acetyl‐β‐D‐ribofuranose (V), gave predominantly the tri‐O‐acetyl derivative of 7‐chloro‐3‐β‐D‐ribofuranosylimidazo[4,5‐b]pyridine (β‐VI) and a small amount of the corresponding α‐anomer (α‐VI). After removal of the acetyl groups, the ribofuranosides β‐VII and α‐VII were obtained as crystalline compounds. It has been shown, that the sugar residue in both anomers is attached to position 3. The anomeric configuration has been assigned with the assistance of several independent methods. Starting from the β‐ribofuranoside β‐VII, l‐deaz

ISSN:0165-0513    

DOI:10.1002/recl.19710900611

出版商:WILEY‐VCH Verlag    

年代:1971

数据来源: WILEY