ISSN:0165-0513    

DOI:10.1002/recl.19730920702

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractThe reaction between methylhydrazine and bis[2‐(dimethylamino)‐5,6‐dimethyl‐4‐pyrimidinyl] carbonate leads to 1‐[2‐(dimethylamino)‐5,6‐dimethyl‐4‐pyrimidinyl]‐2‐methylhydrazine instead of the expected 2‐(dimethylamino)‐5,6‐dimethyl

ISSN:0165-0513    

DOI:10.1002/recl.19730920703

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

ISSN:0165-0513    

DOI:10.1002/recl.19730920704

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractIn the reaction of 6‐bromo‐4‐phenylpyrimidine (1) with lithium isopropylamide at −75°, the open‐chain productN′‐(2‐cyano‐1‐phenyl‐1‐vinylene)‐N‐isopropyl‐formamidine (5) is obtained. On standing, compound5isomerises slowly into 6‐imino‐4‐phenyl‐1‐isopropyl‐1,2‐dihydropyrimidine (6). On reaction of1with lithium isopropylamide at20°, 4‐phenyl‐6‐isopropylaminopyrimidine (7) was formed. Evidence has been presented that7is formed by a complicated series of reactions involving an ANRORC‐mechanism (1

ISSN:0165-0513    

DOI:10.1002/recl.19730920705

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractReaction of NPCl2(NSOCl)2* and Ph2Hg in tetrachloroethane at room temperature yields the monophenyl derivative NPCl2NSOClNSOPh. Treatment of NPCl2(NSOCl)2with AgF2in carbon tetrachloride leads to the formation of NPCl2(NSOF)2. From IR spectra it was determined that the phenyl and fluorine substituents are bonded to sulfur ring atoms.The IR and mass spectra of the two new compounds are discussed.

ISSN:0165-0513    

DOI:10.1002/recl.19730920706

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

Abstract3‐Hydroxyanthranilate oxygenase was purified 250‐930 fold from a hitherto unexamined source, the cytoplasmic fraction of the liver of the African Vervet monkey. The purification steps included extraction, heating, ammonium sulphate fractionation, acetone precipitation, chromatography on Sephadex G‐100 and or G‐200 and calcium phosphategel treatment. Final preparations of the enzyme ranged in specific activity from 5.5‐24.4. Starch‐gel electrophoresis at pH 8.6 indicated protein heterogeneity but more than one of the protein bands was active. Attempts to separate these active forms on DEAE‐ or CM‐cellulose were not successful due to marked instability of the preparations. The enzyme from monkey liver also requires Fe+ +for activity and is protected from inactivation by the presence of dithiothreitol.The Km for 3‐hydroxyant

ISSN:0165-0513    

DOI:10.1002/recl.19730920707

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

Abstract2‐Alkyl‐4‐ethoxycarbonyl‐5‐methyl‐3‐oxo‐2H‐furans (I, R′ = Et) can be prepared at − 20° from ethyl acetoacetate and α‐bromo carboxylic acid chlorides. The furans do not enolize to hydroxyfurans, but behave essentially as unsaturated ketones towards various nucleophiles. With potassium hydroxide, ring opening and closure leads ultimately to 3‐acetyl‐5‐alkyl‐4‐hydroxy‐2‐oxo‐5H‐furans (II); with sodium methoxide the overall process is one of decarboxylation while oxidative decarboxylation with hydrogen peroxide in an alkaline medium yields 2‐alkyl‐4‐hydroxy‐5‐methyl‐3‐oxo‐2H‐furans (IV). As illustrated in Scheme 1 all three processes are thought to be initiated by the addition of a nucleophile

ISSN:0165-0513    

DOI:10.1002/recl.19730920708

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractThe reaction of the three tri‐, the three tetra‐methylbenzenes, 1,3,5‐triethylbenzene, 1,3,5‐tri‐ and 1,2,4,5‐tetra‐isopropylbenzene with methanesulfonic acid, was studied at 180°. The tri‐ and tetra‐methylbenzenes react with formation of a mixture of hydrocarbons which, for long reaction times, contains all the polymethylbenzenes except toluene. Equilibrium isomer ratios for the di‐ and tri‐alkylbenzenes and the tetra‐methylbenzenes are reported. The hydrocarbon products are formed by intramolecular alkyl migration, transalkylation and dealkylation. The xylene equilibration takes place only by transmethylation.The hydrocarbons are sulfonylated further and methylated by the methanesulfonic acid reagent. The sulfonylation is far less important with durene than with hemimellitene andm‐xylene.The reactions are ac

ISSN:0165-0513    

DOI:10.1002/recl.19730920709

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractRaman and infrared spectra of solid POBr3and PSBr3are presented and assigned. The results are discussed in terms of intermolecular interactions.

ISSN:0165-0513    

DOI:10.1002/recl.19730920710

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY

摘要:

AbstractThe directiospecificity and stereochemistry of the addition of nucleophiles (Me2NH, MeS⊖and MeO⊖), of electrophiles (HCl and H3O⊕) and of the free radical C2H5S to Me2P(O)CCSMe and Et2P(O)CCSMe have been studied. The structural assignment of the adducts was based on PMR (Table II); coupling constants2JPHin R2P(O)CHCYZ decrease with increasing electronegati

ISSN:0165-0513    

DOI:10.1002/recl.19730920711

出版商:WILEY‐VCH Verlag    

年代:1973

数据来源: WILEY