摘要:

AbstractThe determination of the electron density distribution of the membrane cross sections of nerve myelin and the discs of the outer segments of retinal rods by a new X‐ray evaluation method indicates, as in the case of the cross‐sectional structure of the photosynthetic membrane, an “asymmetric” mass distribution. In connection with the detection of planar protein lattices in the membranes of photosynthetic bacteria, the chloroplasts of higher plants, erythrocytes, and retinal discs as well as the detection of a new category of lipid characteristics, comprising isothermal confromational and phase changes by specific ligand binding, a basis is established for the development of a general concept of biomembrane st

ISSN:0570-0833    

DOI:10.1002/anie.197205511

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractCooperative conformational transitions of proteins and nucleic acids are of decisive importance to many processes of molecular biology, and particularly to their regulation. They proceedvianumerous interdependent elementary processes, and their kinetics are therefore often complicated. They are frequently also very fast. However, kinetic analyses can be carried out by chemical relaxation methods. The theoretical interpretation is comparatively simple in the case of linear biopolymers. When the linear Ising model extended for kinetics was applied to model peptides and polynucleotides, it provided an insight into the fundamental principles of cooperative transformations.

ISSN:0570-0833    

DOI:10.1002/anie.197205681

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractThe blood pigment hemoglobin (Hb) occurs in red blood cells in a higher concentration than the other proteins which are present. It is therefore particularly suitable for the investigation of genetically induced changes in protein molecules. Unlike the monomeric myoglobin (Mb) of muscle, the blood pigment is tetrameric. Several types of subunits are known that can tetramerize to hemoglobins having different properties. The information for all hemoproteins probably originated from the same primary gene. Doublets of this primary gene have developed differently, and now code different protein species. It is possible to establish from the Hb molecule the possible consequences of a mutation to the conformation and function of a protein molecule.

ISSN:0570-0833    

DOI:10.1002/anie.197205761

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractFluorinated (β)‐sultones are formed on addition of sulfur trioxide to fluorinated olefins. Tetrafluoroethanesultone has been studied particularly thoroughly. The title compounds are characterized by the ease with which they undergo ring cleavage to give,e.g., derivatives of α‐sulfo carboxylic acids, of sulfonic acids, of carboxylic acids, and of sulfuric acid. Fluorinated compounds of this type containing an α‐hydrogen atom are especially valuable in preparat

ISSN:0570-0833    

DOI:10.1002/anie.197205831

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractThe molecular orbital (MO) and valence bond (VB) descriptions of the bonding in metalolefin and ‐acetylene complexes are examined in relation to their ability to explain the known properties of these complexes. It is concluded that whereas there are difficulties with the valence bond description, the molecular orbital description can satisfactorily explain all the known properties of these complexes and has the necessary versatility to enable it to be readily applied to any series of metal‐olefin or ‐acetylene complexes. It is further shown that olefin and acetylene complexes can be usefully divided into two main classes: those that resemble the platinum(II)‐complexes (class S), and are either square‐planar or octahedral with essentially free rotation about the metal‐olefin bond; and those that resemble platinum(0)‐complexes (class T) and are either trigonal planar or trigonal bipyramidal and in which there is no rotation about the metal‐olefin or

ISSN:0570-0833    

DOI:10.1002/anie.197205961

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractVarious problems of solid‐state chemistry can be solved by spectroscopic investigation of the nuclear magnetic resonance (NMR and NQR methods). This progress report presents a survey of the nature of the interactions in the crystal that underlie such measurements, of the observations in the spectrum, and of the information obtainable from it. The field of application of the methods covers both static and dynamic properties of solid

ISSN:0570-0833    

DOI:10.1002/anie.197206071

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

摘要:

AbstractThe puzzle we have to solve is: How did prehistoric man live? Archeologists and scientists, chemists and prehistorians have now joined forces in applying much imagination and pains taking effort to the search for a solution. Some of the fruits of their cooperation are presented in this progress report.

ISSN:0570-0833    

DOI:10.1002/anie.197206201

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197206302

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197206311

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197206321

出版商:Hüthig&Wepf Verlag    

年代:1972

数据来源: WILEY