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1. |
Second‐Sphere Coordination–a Novel Rǒle for Molecular Receptors |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 487-507
Howard M. Colquhoun,
J. Fraser Stoddart,
David J. Williams,
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摘要:
AbstractAlthough it has been appreciated for most of this century that the coordinating influence of many transition metal complexes extends beyond their covalently‐bonded first‐sphere ligands to non‐covalently bound chemical species in the so‐called second‐sphere, it is only recently that the fundamental importance of the phenomenon has been recognized and researched in its most general context. Rapid progress has been possible in this relatively new area of supramolecular chemistry by appealing to the symbiotic relationship that exists between X‐ray crystallographic investigations and synthetic work. The gamut of non‐covalent bonds, including electrostatic forces, hydrogen bonding, charge transfer, and van der Waals interactions are available for exploitation in choosing or designing suitable molecular receptors for particular transition metal complexes. Crown ethers are the synthetic macrocyclespar excellencefor forming adducts with neutral and cationic complexes carrying protic ligands (NH3, H2O, CH3CN, etc.) in their first coordination spheres. Anionic complexes with electron‐rich first‐sphere ligands (e.g. CN⊖) form adducts with polyammonium macrocyclic receptors. In both situations, hydrogen bonds and electrostatic interactions provide the dominant sources of supramolecular stabilization. Spectroscopic studies (UV, IR, and NMR) reveal that the structural integrity of the adducts is usually maintained in solution. The transition metal complexes can be organometallic as well as inorganic. In complexes supporting organic ligands, such as 1,5‐cyclooctadiene, norbornadiene, cyclopentadiene, 2,2′‐bipyridine, and trimethylphosphane, the opportunity exists to match their steric and electronic characteristics with appropriate binding sites in the molecular receptor. With these ligands, the weaker categories of non‐covalent bonding, e.g. charge transfer and van der Waals interactions, assume considerable importance. The phenomenon is also observable with naturally‐occurring receptors such as the cyclodextrins and polyether antibiotics. Moreover, it extends beyond the territory of transition metal complexes to main group complexes such as ammonia‐borane. As far as applications are concerned, it finds expression in areas as diverse as separation sc
ISSN:0570-0833
DOI:10.1002/anie.198604873
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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2. |
The Palladium‐Catalyzed Cross‐Coupling Reactions of Organotin Reagents with Organic Electrophiles [New Synthetic Methods (58)] |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 508-524
John K. Stille,
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摘要:
AbstractThe cross‐coupling of organotin reagents with a variety of organic electrophiles, catalyzed by palladium, provides a novel method for generating a carbon‐carbon bond. Because this mild, versatile reaction is tolerant of a wide variety of functional groups on either coupling partner, is stereospecific and regioselective, and gives high yields of product, it is ideal for use in the synthesis of elaborate organic molecules. When the coupling reaction is carried out in the presence of carbon monoxide, instead of a direct coupling, carbon monoxide insertion takes place, stitching the two coupling partners together and generating a ket
ISSN:0570-0833
DOI:10.1002/anie.198605081
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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3. |
Orthophosphates in the Ternary System Al2O3P2O5H2O |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 525-534
Rüdiger Kniep,
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摘要:
AbstractOrthophosphates of aluminum have been the subject of numerous studies since the middle of the nineteenth century. They have acquired importance in such diverse fields as the earth sciences, chemical engineering, and medicine. The chemical problems associated with this Al2O3P2O5H2O system mainly arise from the marked tendency to form polymeric aluminum orthophosphate complexes in solution; equilibrium is reached only with difficulty, and crystallization of single phases is the exception rather than the rule. However, the crystal structures of several aluminum orthophosphates (including minerals) have been elucidated, and it is now possible to give a systematic description of this class of compounds and the conditions necessary for their format
ISSN:0570-0833
DOI:10.1002/anie.198605251
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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4. |
High‐Pressure Liquid Chromatography (HPLC) of Proteins [New Analytical Methods (29)] |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 535-552
Gerhard Seipke,
Hubert Müllner,
Ulrich Grau,
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摘要:
AbstractThe application of high‐pressure liquid chromatography (HPLC) to proteins has undergone a dramatic development in recent years. Nowadays its many variants expand the repertoire of high‐performance analysis methods available to the protein chemist, which, until now, have been dominated by electrophoretic techniques. The advent of gene technology has resulted in a renaissance of protein chemistry. The new analytical and preparative problems that have thereby emerged are often ideally solved by HPLC methods. HPLC has long since ceased to be solely a laboratory technique; HPLC systems are now being developed for the separation of proteins–particularly those of great pharmaceutical interest – on a 100‐g scale. The range of applications of analytical and preparative HPLC will be illustrated by two examples of pharmaceutical importance—insulin and in
ISSN:0570-0833
DOI:10.1002/anie.198605351
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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5. |
Reduced Cobalt‐meso‐Tetraphenylporphyrin Complexes: Synthesis and Structure of [Na(thf)3]2[Co(TPP)] |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 553-554
Stefano Ciurli,
Sandro Gambarotta,
Carlo Floriani,
Angiola Chiesi‐Villa,
Carlo Guastini,
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ISSN:0570-0833
DOI:10.1002/anie.198605531
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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6. |
Epoxidation of Olefins with Elemental Fluorine in Water/Acetonitrile Mixtures |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 554-555
Shlomo Rozen,
Michael Brand,
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ISSN:0570-0833
DOI:10.1002/anie.198605541
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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7. |
[MoR(η3‐C3H5)3], R = Alkyl: Alkylmolybdenum Complexes with Agostic CH ⇀ Mo Bond |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 555-556
Reinhard Benn,
Sigrid Holle,
Peter W. Jolly,
Richard Mynott,
Carlos C. Romão,
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ISSN:0570-0833
DOI:10.1002/anie.198605551
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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8. |
Diastereoselective Synthesis of Functionalized Tetrahydrofuran Derivatives from γ‐Lactols |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 556-557
Christiane Brückner,
Hiltrud Lorey,
Hans‐Ulrich Reissig,
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ISSN:0570-0833
DOI:10.1002/anie.198605561
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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9. |
Complex‐Induced Fragmentation of As4S4: Stabilization of an As2S3Ligand |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 557-558
Henri Brunner,
Heike Kauermann,
Bernd Nuber,
Joachim Wachter,
Manfred L. Ziegler,
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ISSN:0570-0833
DOI:10.1002/anie.198605571
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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10. |
Heterogeneous Catalysis of Ammonia Synthesis at Room Temperature and Atmospheric Pressure |
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Angewandte Chemie International Edition in English,
Volume 25,
Issue 6,
1986,
Page 558-559
Ken‐ichi Aika,
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ISSN:0570-0833
DOI:10.1002/anie.198605581
出版商:Hüthig&Wepf Verlag
年代:1986
数据来源: WILEY
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