摘要:

AbstractBirefringence induced in a material by application of an electric field is known as the Kerr effect. The great sensitivity of this property to variations of molecular geometry and environment has made it the basis of a potent method for studying the conformations of molecules. It has, in addition, been effectively applied to investigations of the geometry of solvation and of solute aggregation. An outline is presented of the general technique of measurement of the Kerr effect, the extraction of directed effective polarizabilities of solute molecules and of structural groups, the calculation of theoretical Kerr constants for candidate structures of molecules, and the procedures used to determine solute conformations. The scope and limitations of the method are illustrated by specific conformational problems drawn from the literature. In the case of highly flexible molecules analysis of the measured Kerr constant is inhibited by uncertainties in conformational energy data. This paper is concerned mainly with the specification of detailed conformational energy data. This paper is concerned mainly with the specification of detailed conformational features of molecules. Reference is made, however, to the utilization of pulsed orienting fields to study shapes and dimensions of biological macromolecules.

ISSN:0570-0833    

DOI:10.1002/anie.197706633

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractOxo compounds whose coordination polyhedra have a planar structure are a rarity in solid state chemistry. The present state of this research area provides a wealth of interesting principles concerning one‐, two‐, and three‐dimensional linkage of square‐planar structural units. In certain cases the environment of these units in solids requires new conceptual models for the chemical

ISSN:0570-0833    

DOI:10.1002/anie.197706741

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractThe era of spectacular developments in the field of antibiotics appears to be over. Ever greater efforts are needed to find ever fewer new antibiotics. The view that well‐considered hypotheses can lead as successfully as proven results to further research is supported by the establishment of five theses. “Non‐classical” screening methods and the search for secondary metabolites with unusual properties can provide a rich

ISSN:0570-0833    

DOI:10.1002/anie.197706871

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

摘要:

AbstractATP and ADP are transferred across the inner mitochondrial membrane by means of a carrier (translocator), an inner membrane integral lipoprotein. Translocation of the adenine nucleotides occurs in two steps: specific binding and transport. By using substrate analogs with modified adenine, phosphate, or ribose moieties it is possible to check which structural properties of the substrate are essential for binding and transport.

ISSN:0570-0833    

DOI:10.1002/anie.197706951

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707021

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707042

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707051

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707072

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707081

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY

ISSN:0570-0833    

DOI:10.1002/anie.197707091

出版商:Hüthig&Wepf Verlag    

年代:1977

数据来源: WILEY