ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;As in other aspects of oncologic surgery, the pathologist plays a key role in the surgical management of neoplasms of the head and neck. Communication between the pathologist and the head and neck surgeon is of utmost importance. In patients with cancer, the dialogue between these two parties will continue from the initial presentation of the patient, to the operative procedure, and through years of follow‐up and surveillance. Three major areas of pathology that are of concern to the head and neck surgeon are discussed here. These are the management of squamous cell carcinoma of the head and neck, thyroid cancer and hyperparathyroidism.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;Metastatic cystic squamous cell carcinoma of the neck may simulate benign cystic lesions of this region, and it represents a diagnostic challenge to the cytopathologist and surgical pathologist. From a cytologic perspective, the main task is to determine whether the squamous component in these lesions is benign, malignant, or indeterminate, and whether additional clinical evaluation is warranted to determine the nature of this lesion. Often, the definitive diagnosis of a cystic squamous lesion of the neck is made by histologic evaluation of the entire lesion after surgical resection. Once the diagnosis of a metastatic cystic squamous cell carcinoma is established, clinical evaluation should be initiated to find the primary carcinoma. A case of cystic squamous cell carcinoma in the upper neck is presented with a discussion of its cytologic and histologic diagnosis, and its differential diagnoses.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;Conventional squamous cell carcinoma (SCC) of the larynx presents as a largely flat or ulcerated lesion and is usually categorized histologically asin situ, superficially invasive, or deeply invasive. Papillary and exophytic squamous cell carcinomas of the larynx represent uncommon but distinct subtypes of SCC. As implied by their designations, these tumor types show predominant papillary or exophytic growth in the form of finger‐like or filiform and broad‐based bulbous fronds, respectively. Both tumor types are composed of cytologically malignant squamous epithelium. The following case illustrates the clinical and pathologic features of papillary squamous cell carcinoma and emphasizes the importance of distinguishing this entity from conventional squamous cell carcinoma of the larynx.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;Basaloid squamous cell carcinoma is a high‐grade, aggressive variant of squamous cell carcinoma with a predilection for the larynx, hypopharynx, tonsils, and base of the tongue. It has rarely been reported in the sinonasal region. A 75‐year‐old woman had a mass in the left ethmoid sinus. She had a history of olfactory neuroblastoma of the nasal cavity diagnosed 6 years previously. The following case highlights the clinical and pathologic features of basaloid squamous cell carcinoma and emphasizes the broad differential diagnosis of this lesion as it presents in the sinonasal region.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;An 18‐year‐old man with a nasal NK/T‐cell lymphoma had a midfacial destructive process. Sinonasal tract lymphomas represent heterogeneous diseases that can be clinically aggressive. Synonyms have included polymorphic reticulosis, lethal midline granuloma, midline malignant reticulosis, and idiopathic midline destructive disease. Although these terms have been used synonymously with sinonasal lymphomas, they are inaccurate and no longer valid. Nonneoplastic lesions, such as inflammatory and infectious diseases, as well as numerous benign and malignant neoplasms of the sinonasal tract, may all result in a destructive process occurring in the midline aspect of this region. The current designations for these nasal and paranasal sinus lymphomas include angiocentric immunoproliferative lesions, peripheral T‐cell lymphomas, and more recently, nasal and nasal‐type NK/T‐cell lymphomas.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;Mucoepidermoid carcinoma (MEC) is defined as a salivary tumor composed of mucinous, squamous, and intermediate cells in varying proportions. As MEC varies in grade and cellular composition, it may assume many different histologic appearances. A recurrent parotid mucoepidermoid carcinoma is presented here to illustrate 1) the potential for diagnostic confusion when MEC recurs with only one predominant cell type, and 2) issues concerning the reproducibility of tumor grading.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;Necrotizing sialometaplasia is a benign self‐limited condition of salivary glands most commonly involving the palate, although extrapalatal involvement also occurs. The exact pathogenesis is unknown, but the most widely accepted theory is that necrotizing sialometaplasia develops as a result of ischemic injury to the salivary gland lobule, Necrotizing sialometaplasia has been mistaken histologically for carcinoma, particularly mucoepidermoid and squamous carcinomas. Misdiagnosis can be avoided by appreciating the characteristic maintenance of lobular architecture despite necrosis of salivary gland tissue and the presence of squamous metaplasia within residual ducts and acini. The recognition of necrotizing sialometaplasia as a potential simulator of carcinoma is essential in sparing patients inappropriate and excessive therapy.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID

摘要:

&NA;The diagnostic criteria for thyroid papillary carcinoma are well established. The cytomorphologic features (i.e., nuclei) represent the single most important diagnostic parameter for thyroid papillary carcinoma. Based on the nuclear characteristics, a diagnosis of thyroid papillary carcinoma can be made by fine needle aspiration biopsy (FNAB) and can be established in the absence of papillary architecture. Those thyroid papillary carcinomas devoid of papillary architecture have been termed the follicular type of thyroid papillary carcinoma. The diagnosis of thyroid papillary carcinoma is generally straightforward; however, those tumors without papillary growth may be diagnostically challenging and misinterpreted as follicular adenoma or carcinoma. Further, the presence of an associated lymphocytic infiltrate or cytoplasmic alterations may confuse the diagnostic issues. The following case will serve as a platform to reaffirm the diagnostic criteria for thyroid papillary carcinoma and to discuss its differential diagnosis with follicular epithelial lesions with similar appearances.

ISSN:1082-9784    

出版商:OVID    

年代:2000

数据来源: OVID