|
|
| 11. |
Oral toxicity of trichlorobenzyl chloride and its acid derivative |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page 67-70
Frederick R. Johannsen,
George J. Levinskas,
Preview
|
PDF (377KB)
|
|
摘要:
AbstractThe acute rat oral LD50 of 2,4,6‐Trichlorobenzyl chloride (TCBC) was determined to be 3075 mg/kg. When male and female rats were administered 1500 and 3000 ppm TCBC in the diet for 3 weeks, marked retardation in weight gain was observed. Reductions in food consumption were noted in both groups of treated male, but not female, rats. All blood chemistry and urinalysis parameters including those indicative of liver injury, were within the range of normal limits. Gross necropsy revealed pale livers in all high‐dose rats and the majority of low‐dose animals. Gross observations correlated with observation of degenerative hepatic changes (irregularity of cell and nuclear size, cord pattern, edema and cytoplasmic alterations) following microscopic evaluation. Rats and dogs administered up to 100 ppm trichlorobenzoic acid (TCBA) in the diet for 90 days exhibited no effects considered related to trea
ISSN:0260-437X
DOI:10.1002/jat.2550070112
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
| 12. |
R. L. Dixon (ed). Reproductive Toxicology (Target Organ Toxicology Series). Raven Press, New York, 1985; 368 pp., $76.50 E. J. CALABRESE Toxic Susceptibility—Male/Female Differences A Wiley‐Interscience Publication, John Wiley&Sons, New York, 1985; 336 pp., £57.45 |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page 71-71
Laszlo Magos,
Preview
|
PDF (131KB)
|
|
ISSN:0260-437X
DOI:10.1002/jat.2550070113
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
| 13. |
K. R. Spurny (ed). Physical and Chemical Characterization of Individual Airborne Particles. Ellis Horwood, Chichester, 1986; 418 pp., ISBN 0‐85312‐793‐X, £55.00 |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page 72-73
J. N. Pritchard,
Preview
|
PDF (295KB)
|
|
ISSN:0260-437X
DOI:10.1002/jat.2550070118
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
| 14. |
B. L. Carson, H. V. Ellis and J. L. McCann (Eds). Toxicology and Biological Monitoring of Metals in Humans Including Feasibility and Need. Lewis Publishers, Chelsea, Michigan 328 pp, £45.95 |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page 73-74
L. Magos,
Preview
|
PDF (226KB)
|
|
ISSN:0260-437X
DOI:10.1002/jat.2550070121
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
| 15. |
Jerry F. Stara and Linda S. Erdreich. Advances in health risk assessment for systemic toxicants and chemical mixtures. Toxicology and industrial health, vol. 1, No. 4. Princeton Scientific Publishing, Princeton, N. J. 364pp. £53.35 |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page 74-74
L. Magos,
Preview
|
PDF (97KB)
|
|
ISSN:0260-437X
DOI:10.1002/jat.2550070122
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
| 16. |
Masthead |
| |
Journal of Applied Toxicology,
Volume 7,
Issue 1,
1987,
Page -
Preview
|
PDF (89KB)
|
|
ISSN:0260-437X
DOI:10.1002/jat.2550070101
出版商:John Wiley&Sons, Ltd.
年代:1987
数据来源: WILEY
|
|
首页
Volume 7 issue 1