| 31. |
Varying Amounts of Tumor Cells in the Bone Marrow of Patients with Nonmetastatic Colorectal Cancer |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 184-186
H. Silly,
M. Wilders-Truschnig,
R. Brezinschek,
H.-P. Brezinschek,
M. Schmid,
I. Kuss,
K. Mucher,
H. Stöger,
H. Samonigg,
Preview
|
PDF (1212KB)
|
|
摘要:
Background: The study focuses on the total amount of tumor cells in the bone marrow of nonmetastatic colorectal cancer patients (Tl-4 NO-3 MO) after radical resection of the primary tumor. Patients and Method: The bone marrow of 7 patients was examined for tumor cells by means of immunocytochemistry methods. The bone marrow cells were purified by density centrifugation, cytospin slides were developed using a monoclonal antibody against epithelial cells (cytokeratin component number 18) and alkaline phosphatase – anti-alkaline phosphatase staining. Results: Five out of 7 patients revealed a varying number of tumor cells in their bone marrow: Whereas in 3 patients only a low number was found (1, 3, 4 tumor cells/106 mononuclear cells, respectively), a high number of tumor cells was detected in 2 patients (48, 60 tumor cells/106 mononuclear cells, respectively). Conclusion: Since bone marrow puncture was performed after radical resection of the primary tumor, the amount of tumor cells in the bone marrow of these patients reflects the residual individual tumor load. Further studies should evaluate the impact of varying numbers of residual tumor cells in the bone marrow on the development of generalized metastatic diseas
ISSN:0378-584X
DOI:10.1159/000218406
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 32. |
Wilke H, et al.: Phase II study with folinic acid, etoposide, 5-fluorouracil and cisplatin (FLEP) for advanced gastric cancer. Onkologie 1994;17:154-157 (this issue) |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 188-188
Preview
|
PDF (376KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218407
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 33. |
Wilsede – Schule für Onkologie und Hämatologie |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 190-190
Preview
|
PDF (150KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218408
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 34. |
Ehrendoktortitel der Universität Basel für Thomas Karger |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 191-191
Preview
|
PDF (434KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218409
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 35. |
Buchbesprechungen – Book Reviews |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 192-193
Preview
|
PDF (867KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218410
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 36. |
Mitteilungen onkologischer Gesellschaften – Reports of Oncological Societies |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 194-202
Preview
|
PDF (4039KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218411
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 37. |
Hinweise für Autoren – Instructions to Authors |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page 203-204
Preview
|
PDF (1143KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218412
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
| 38. |
Author Index |
| |
Onkologie,
Volume 17,
Issue 2,
1994,
Page -
Preview
|
PDF (4935KB)
|
|
ISSN:0378-584X
DOI:10.1159/000218515
出版商:S. Karger GmbH
年代:1994
数据来源: Karger
|
首页
