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1. |
Fiat Lux |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 1-1
Michael L.J. Apuzzo,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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2. |
Gutenberg'sBible: Past as Prologue |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 2-4
Arun Amar,
Daniel Sullivan,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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3. |
Gutenberg Recycled |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 5-8
Gerald Gillespie,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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4. |
Neurosurgery Onlineand the Internet: Prospects for the Next Decade |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 9-11
Lyndon Holmes,
Timothy Grayson,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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5. |
Functional Radiosurgery |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 12-20
Douglas Kondziolka,
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摘要:
ALTHOUGH THE APPLICATION of stereotactic radiosurgery for the management of functional brain disorders began in 1951, almost 50 years elapsed before it received appropriate attention. Radiosurgical techniques are used to create image-guided, physiological inactivity or focally destructive brain lesions without neurophysiological guidance. The lack of neurophysiological guidance remains the greatest argument against the use of radiosurgery for selected disorders. Current anatomic targets include the trigeminal nerve (for trigeminal neuralgia), the thalamus (for tremor or pain), the cingulate gyrus or anterior internal capsule (for pain or psychiatric illness), the globus pallidus (for symptoms of Parkinson's disease), and the hippocampus (for epilepsy). The use of radiosurgery as a "lesion generator" is based on extensive animal studies that defined the dose, volume, and temporal response of the irradiated tissue. The usefulness of radiosurgery has been compared with that of microsurgical, percutaneous, and electrode-based techniques used for functional neurological disorders. At present, the long-term results after functional radiosurgery procedures remain to be documented. The current indications and expected outcomes after radiosurgery are discussed.
ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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6. |
Functional Radiosurgery |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 20-21
Patrick Kelly,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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7. |
Functional Radiosurgery |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 21-22
Philip Gildenberg,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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8. |
Mild Hypothermia as a Protective Therapy during Intracranial Aneurysm Surgery: A Randomized Prospective Pilot Trial |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 23-32
Bradley Hindman,
Michael Todd,
Adrian Gelb,
Christopher Loftus,
Rosemary Craen,
Armin Schubert,
Michael Mahla,
James Torner,
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摘要:
OBJECTIVE:To conduct a pilot trial of mild intraoperative hypothermia during cerebral aneurysm surgery.METHODS:One hundred fourteen patients undergoing cerebral aneurysm clipping with (n = 52) (World Federation of Neurological Surgeons score ≤III) and without (n = 62) acute aneurysmal subarachnoid hemorrhage (SAH) were randomized to normothermic (target esophageal temperature at clip application of 36.5°C) and hypothermic (target temperature of 33.5°C) groups. Neurological status was prospectively evaluated before surgery, 24 and 72 hours postoperatively (National Institutes of Health Stroke Scale), and 3 to 6 months after surgery (Glasgow Outcome Scale). Secondary outcomes included postoperative critical care requirements, respiratory and cardiovascular complications, duration of hospitalization, and discharge disposition.RESULTS:Seven hypothermic patients (12%) could not be cooled to within 1°C of target temperature; three of the seven were obese. Patients randomized to the hypothermic group more frequently required intubation and rewarming for the first 2 hours after surgery. Although not achieving statistical significance, patients with SAH randomized to the hypothermic group, when compared with patients in the normothermic group, had the following: 1) a lower frequency of neurological deterioration at 24 and 72 hours after surgery (21 versus 37-41%), 2) a greater frequency of discharge to home (75 versus 57%), and 3) a greater incidence of good long-term outcomes (71 versus 57%). For patients without acute SAH, there were no outcome differences between the temperature groups. There was no suggestion that hypothermia was associated with excess morbidity or mortality.CONCLUSION:Mild hypothermia during cerebral aneurysm surgery is feasible in nonobese patients and is well tolerated. Our results indicate that a multicenter trial enrolling 300 to 900 patients with acute aneurysmal SAH will be required to demonstrate a statistically significant benefit with mild intraoperative hypothermia.
ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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9. |
Mild Hypothermia as a Protective Therapy during Intracranial Aneurysm Surgery: A Randomized Prospective Pilot Trial |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 32-33
Robert Solomon,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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10. |
Mild Hypothermia as a Protective Therapy during Intracranial Aneurysm Surgery: A Randomized Prospective Pilot Trial |
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Neurosurgery,
Volume 44,
Issue 1,
1999,
Page 33-33
Randall Porter,
Paul Detwiler,
Robert Spetzler,
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ISSN:0148-396X
出版商:OVID
年代:1999
数据来源: OVID
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