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11. |
Indocyanine Green Test Is a Reliable Indicator of Postoperative Liver Function in Biliary Atresia |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 61-65
Akio,
Kubota Akira,
Okada Yuichi,
Fukui Hisayoshi,
Kawahara Kenji,
Imura Shinkichi,
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摘要:
In order to evaluate liver function in postoperative biliary atresia (BA) patients, the indocyanine green (ICG) clearance test was performed. Nineteen patients, ranging in age from 2 to 9 years, were classified into three groups. Group I were those who had no jaundice throughout the postoperative period (n = 9), Group II were those who had recurrent or intermittent jaundice (n = 7), and Group III were those who had persistent jaundice after hepatic portojejunostomy (n = 3). Forty-four volunteers of comparative age and sex served as controls to establish a normal range of ICG-K values in infants and children. The normal minimal ICG-K value in those 2–9 years of age was defined as 0.19. ICG-K values in BA patients were 0.262 ± 0.073 (Group I), 0.150 ± 0.060 (Group II), and 0.054 ± 0.011 (Group III). All nine patients with ICG-K below the normal level had esophageal varices, and seven of nine had a history of gastrointestinal hemorrhage. Two patients with ICG-K values within the normal range had esophageal varices, and none had a history of gastrointestinal hemorrhage. Five of nine patients with ICG-K values below normal had low serum albumin levels, and all had low prealbumin levels. Of those with ICG-K within the normal range, none had low serum albumin or prealbumin levels. On the other hand, serum bilirubin and other liver function tests did not accurately reflect clinical findings. In conclusion, the ICG test using the ICG-K value was confirmed to be a reliable indicator of postoperative liver function in BA patients.
ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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12. |
Horizontal Transmission of Hepatitis B Virus in Children |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 66-69
Shun-Chien,
Hsu Mei-Hwei,
Chang Yen-Hsuan,
Ni Hong-Yuan,
Hsu Chin-Yun,
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摘要:
Horizontal transmission of hepatitis B virus (HBV) is responsible for about half of the hepatitis B surface antigen (HBsAg) carriers in Taiwan. To investigate the routes and risk factors of horizontal HBV transmission, 131 HBsAg carrier children of HBsAg seronegative mothers were compared with 98 age-matched children seronegative for all hepatitis B markers. Possible factors influencing transmission of HBV, including family size, age at attending kindergarten, frequency of intramuscular injection during infancy and at the toddler stage, contact with HBsAg carriers, and HBV status of parents, siblings and caretakers were studied by questionnaire survey. Intramuscular injection frequency during infancy and at the toddler stage and prevalence of HBsAg positivity among siblings were significantly higher in carrier children than in the control group. Other factors studied were not different in these two groups. The results indicated that unsterilized, multiple intramuscular injections and intrafamilial spread among siblings might be the major routes of horizontal HBV transmission in children in Taiwan.
ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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13. |
Patterns of Hepatitis B Virus DNA Integration in Liver Tissue of Children with Chronic Infections |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 70-74
Yasuhiro,
Goto Jun,
Yoshida Kiyotaka,
Kuzushima Makoto,
Terashima Tsuneo,
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摘要:
Although an integration of hepatitis B virus (HBV) DNA in children with chronic HBV infection has been documented at early phases of the disease, the incidence of this process is not known. Therefore we examined nine liver DNA specimens from chronic HBV carriers ages 5–14 years and one sample from a neonate delivered of a carrier mother, in order to determine the HBV DNA patterns of these patients at different ages and phases of chronic infection. The integrated HBV DNA was detected by Southern blot hybridization and analyzed by molecular cloning. Southern blot showed a smear pattern of HBV DNA integration in four of six chronic hepatitis patients (ages 5–14), as well as in one asymptomatic carrier (age 12). Multiple and random integrations occurred during chronic infections in childhood. The neonate did not, however, show signs of any integrations, suggesting that integration starts after HBV multiplication. A band pattern that suggested clonal growth of integrated liver cells was found in a chronic active hepatitis patient (age 9) and in one of two hepatocellular carcinoma patients (age 11). Molecular cloning in two cases with chronic active hepatitis showed that the HBV genome structure was preserved in five of six HBV DNA inserts. Our findings confirm that HBV DNA integration can occur at early stages of chronic HBV infection. In Japanese children, the process of integration seems to be common regardless of HBeAg/anti-HBe status. Thus, repetitive liver biopsies in chronic hepatitis B are useful not only to provide prognostic information referring to the histological progress of the disease but also to reflect the change of HBV DNA pattern in liver tissue during follow-up
ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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14. |
Ingestion of Caustic Alkali Farm Products |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 75-77
Gary,
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摘要:
Since the Poison Prevention Packaging Act took effect, the number of ingestions of caustic alkali from household products has been significantly reduced. Commercial caustic alkalis used on farms, however, were not included in this legislation. Fourteen children over a 5 year period were seen after ingestion of commercial caustic alkalis used on farms. Seven of the children had ingested liquid pipeline cleaners and seven had ingested solid agents used for a variety of reasons. Six of seven children ingesting liquid agents did so from nonoriginal containers into which the caustic had been transferred for convenience. All seven children ingesting solid agents did so from the original container. Eight of the 14 children were found to have second-degree or worse esophageal involvement. Both solid and liquid caustic agents used commercially on farms can cause significant morbidity. Development of a child-resistant container for daily transfer of liquid pipeline agents could be helpful in preventing injuries from liquid pipeline cleaners. Pediatric gastroen-terologists as well as primary care physicians in rural areas should be familiar with this type of injury and should take an active role in instructing parents of children living on farms to prevent such injuries. Extension of the Poison Prevention Packaging Act to caustic alkalis used on farms needs to be considered
ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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15. |
Intracranial Hemorrhage due to Vitamin K Deficiency in Breast‐Fed Infants with Cholestasis |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 78-80
John,
Bancroft Mitchell,
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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16. |
Association of Paucity of Interlobular Bile Ducts with Prune Belly Syndrome |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 81-86
Prapun,
Aanpreung Bruce,
Beckwith Stanley,
Galansky Martin,
Koyle Ronald,
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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17. |
Arterioportal Fistula in Infancy |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 87-89
Matthias,
Gorenflo Jgn,
Waldschmidt Georg,
Bein Wolfgang,
Flocken Martin,
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PDF (536KB)
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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18. |
Duodenal Web Presenting with Gastrointestinal Bleeding in a Seven‐Month-Old Infant |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 90-92
Rajeev,
Nagpal Louise,
Schnaufer Steven,
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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19. |
Acquired Colonic AtresiaA Rare Sequela of Necrotizing Enterocolitis |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 93-97
A. Mares,
E. Freud,
Y. Efrati,
J. Bar-Ziv,
E. Maor,
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PDF (442KB)
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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20. |
Congenital Esophageal Stenosis Treated by Balloon Dilation |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 16,
Issue 1,
1993,
Page 98-101
Priscila Garau,
Susan Orenstein,
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PDF (283KB)
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ISSN:0277-2116
出版商:OVID
年代:1993
数据来源: OVID
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