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21. |
Bile Composition of Adult Baboons Is Influenced by Breast Versus Formula Feeding |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 121-126
Glen Mott,
Evelyn Jackson,
C. McMahan,
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摘要:
We tested the hypothesis that infant cholesterol intake and breast- versus formula-feeding influence the bile cholesterol saturation index and bile acid conjugate composition in adult baboons at 7–8 years of age. We also measured the influence of the postweaning intake of dietary cholesterol and fat (saturated and unsaturated) on the effects of the infant diets. The 80 baboons were derived from six sires and 80 dams and randomly assigned at birth to breast-feeding or to one of three formulas containing about 2, 30, or 60 mg cholesterol/dl. After weaning at 16 weeks of age the animals were assigned to one of four adult diets, which contained 0.01 or 1.0 mg/kcal of cholesterol containing 40% of calories from saturated or unsaturated fat. The bile cholesterol saturation index was significantly higher at 7–8 years of age in baboons breastfed as infants compared with those fed formula (87.0% versus 72.8%, p < 0.004). The cholesterol saturation index was not significantly different among the three formula groups. Among baboons who were breast-fed and subsequently fed saturated fat as adults, the glycine/ taurine (G/T) ratios of the bile acid conjugates were about three times those of baboons fed unsaturated fat (1.53 versus 0.47); whereas among formula-fed animals the type of fat did not influence the G/T ratio (interaction, p = 0.022). Adult baboons fed the three formulas in infancy had an inverse relationship of the G/T ratio to the level of formula cholesterol (p < 0.05), We conclude that breastfeeding and formula feeding in infancy differentially affect biliary lipid composition and its response to dietary cholesterol and fat in adulthood. These deferred effects of infant diet on bile lipid composition may influence gallstone formation and intestinal cholesterol and bile acid metabolism.
ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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22. |
Neonatal Hepatitis Syndrome with Paucity of Interlobular Bile Ducts in Cystic Fibrosis |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 127-130
Katryn Furuya,
Eve Roberts,
Gerard Canny,
M. Phillips,
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摘要:
A male infant presenting with neonatal hepatitis syndrome, characterized by conjugated hyperbilirubinemia and very mild liver function test abnormalities, at 2 weeks of age was found to have no excretion of radioisotope into the intestinal tract on hepatobiliary scan. Liver biopsy revealed severe interlobular bile duct paucity. Other features of Alagille's syndrome were not present; other conditions frequently associated with interlobular bile duct paucity were also excluded. Subsequently, the infant was found to have cystic fibrosis. Cystic fibrosis is thus another disease that may be associated with paucity of interlobular bile ducts presenting as neonatal hepatitis syndrome, and this represents a different pathogenesis of cholestatic jaundice in neonates with cystic fibrosis besides those previously recognized.
ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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23. |
Biliary Infusion Therapy in the Inspissated Bile Syndrome of Cystic Fibrosis |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 131-135
Jonathan Evans,
Donald George,
Daniel Mollit,
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摘要:
A 3.5-month-old white boy was born with meconium ileus, peritonitis, and jejunal atresia from cystic fibrosis. He subsequently developed unrelenting and severe extrahepatic biliary obstruction as demonstrated by liver biopsy showing periportal inflammation, cholestasis, and fibrosis. Surgical exploration confirmed the diagnosis of extrahepatic biliary obstruction by severely inspissated bile. A cholecystostomy tube was left in place. The cholestasis remained unresponsive to conservative medical therapy. The obstruction was relieved by hydrostatic infusion of 2%N-acetylcysteine into the biliary tree over a 6-day period. The child also received concurrently four i.v. injections of synthetic cholecystokinin. This therapeutic modality was thought to be both safe and effective.
ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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24. |
Hemobilia in a Child with Liver Abscess |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 136-138
A. Khalil,
V. Chadha,
R. Mandapati,
N. Mathur,
S. Mittal,
P. Gulati,
V. Chowdhury,
S. Tyagi,
M. Khalilullah,
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摘要:
Hemobilia in children is rare and has so far been described only as a complication of blunt abdominal trauma. A case of hemobilia secondary to liver abscess treated successfully by selective arterial embolization is described. Hemobilia should be considered in any case of gastrointestinal hemorrhage before any operative intervention is undertaken.
ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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25. |
Abnormal Pattern of Distribution of IgG Subclasses in Children with Chronic Hepatitis B Virus Infection |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 139-140
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PDF (294KB)
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ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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26. |
The Use of H2Breath Test in Assessment of Quantitative Lactose Malabsorption and Milk Intake |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 141-141
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ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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27. |
Creamatocrit and pH Measurements of Human Milk |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 142-143
R. Ceriani,
L. Galli,
E. Reali,
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PDF (167KB)
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ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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28. |
Gastrointestinal PathologyAn Atlas and Text |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 144-144
C. Fenoglio-Preiser,
P. Lantz,
M. Listrom,
M. Davis,
F. Rilke,
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PDF (219KB)
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ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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29. |
A Color Atlas of the Digestive System |
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Journal of Pediatric Gastroenterology and Nutrition,
Volume 12,
Issue 1,
1991,
Page 145-145
Martin Maksimak,
R. Pounder,
M. Allison,
A. Dhillon,
Asaria Ashkenazi,
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PDF (116KB)
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ISSN:0277-2116
出版商:OVID
年代:1991
数据来源: OVID
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