1. |
News |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 61-61
&NA;,
Preview
|
PDF (84KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
2. |
Data Mining in Pharmacovigilance |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 63-64
Patrick M. Purcell,
Preview
|
PDF (105KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
3. |
Coming in from the ColdBenchmarking and Pharmacovigilance |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 65-68
Chris Holmes,
Preview
|
PDF (218KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
4. |
When is a Food a Medicine? |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 69-69
Ian Shaw,
Preview
|
PDF (117KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
5. |
Clinical Applications of Quantitative Computed Tomography in Chronic Lung Disease |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 71-78
David G. Parr,
Preview
|
PDF (271KB)
|
|
摘要:
Improved understanding of the pathophysiology of chronic lung disease at a molecular and cellular level has led to the concept of targeted pharmacotherapy for the modification of disease progression. The limitations of conventional physiological measures of disease have prompted the development of alternative methods for determining outcome in therapeutic trials. Technological improvements in computed tomography, coupled with the development of software for the automated calculation of densitometric parameters have resulted in more specific and sensitive measures of disease than traditional methods. Such techniques have been applied principally to the assessment of changes in lung parenchyma in patients with chronic obstructive pulmonary disease and, in particular, in patients with α1-antitrypsin deficiency where they have been used as an outcome measure in a therapeutic trial of α1-antitrypsin augmentation. Measurement of airway dimensions has proved more problematic and most studies have, until recently, been limited to anthropomorphic phantoms orex-vivospecimens.This paper reviews the development of quantitative computed tomography and explores its potential role as an outcome measure in trials of disease-modifying therapy.
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
6. |
IFAPP News |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 79-97
&NA;,
Preview
|
PDF (263KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
7. |
SPM News |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 99-100
&NA;,
Preview
|
PDF (144KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
8. |
Major Pharmaceutical ConferencesJune − August 2003 |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 101-103
&NA;,
Preview
|
PDF (97KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|
9. |
Workplace |
|
International Journal of Pharmaceutical Medicine,
Volume 17,
Issue 2,
2003,
Page 105-109
&NA;,
Preview
|
PDF (122KB)
|
|
ISSN:1364-9027
出版商:ADIS
年代:2003
数据来源: ADIS
|