ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00551.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

SummaryCanine granulocytic ehrlichial organisms were transmitted from an infected dog from Missouri to two male, 10‐month‐old dogs by an intravenous injection of whole blood. Physical or behavioral abnormalities were not detected during the 98 days of evaluation other than a mild pyrexia from Day 18 to 20. Ehrlichial morulae were found in blood granulocytes of Dog 1 from Day 13 to 44 and of Dog 2 from Day 14 to 34 with the peak rickettsemia occurring on Day 16 for both dogs. By Day 21 after inoculation, both dogs had positive titers to Ehrlichia canis. The highest titers for both dogs were found 63 days after inoculation, after which the titers decreased. Most of the hematologic abnormalities (i.e., neutropenia, lymphocytosis, thrombocytopenia) and fever occurred between 18 and 24 days after inoculation. The pathologic bases of these abnormalities were not investigated but their concurrent presence suggested an association with the dogs' immunologic responses to the granulocytic ehrlichial agent. Results from the study indicated that the canine granulocytic ehrlichial agent of Missouri may produce subclinical infections and suggested that dogs may be able to clear the organism without antimicrobial ther

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00552.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00553.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

SummarySerum levels of the amino‐terminal peptide of Type III procollagen (P‐III‐P) were assayed by radioimmunoassay in 48 Rhesus monkeys from 0.7 to 26.4 years of age. Serum P‐III‐P levels in ten juvenile monkeys (0.7‐4.7 yrs.) were significantly higher (84.5 ± 66.2 ng/ml; p = 0.05) and ranged from 29.6 to 238.0 ng/ml as compared with 38 monkeys over 5 years of age (21.7 ± 9.4 ng/ml), which ranged from 8.5 to 55.5 ng/ml. No significant differences in serum P‐III‐P levels were observed between any age groups over 5 years of age (5–10, 10–15, 15–20, and>20) or between male and female monkeys

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00554.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

SummaryA manual kit for determining serum 5'nucleotidase (5'NT, EC 3.1.3.5) activity was adapted for use with rat samples on a large discrete clinical chemistry analyzer. The precision of the method was good (within‐run C.V. = 2.14%; between‐run C.V. = 5.5%). A comparison of the new automated method with a manual and semi‐automated method gave regression statistics of y = 1.18x − 3.66 (Sy·x = 4.54), and y = 0.733x + 1.97 (Sy·x = 1.69), respectively. Temperature conversion factors provided by the kit manufacturer for human samples were determined to be inaccurate for converting results from rat samples. Analysis of components contributing to normal variation in rat serum 5'NT activity showed age and sex to be major factors. Increased serum 5'NT activity was observed in female rats when compared to male rats beginning at about 5 to 6 weeks of age. An analysis of variance of serum 5'NT, alkaline phosphatase, and GGT activities observed over a 9‐week period in normal rats suggests several advantages for 5'NT as a predictor of biliary lesi

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00555.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

摘要:

SummaryEchinocytes were evaluated quantitatively in both healthy and sick dogs and compared with red blood cell (RBC) morphology on Wright's‐stained blood smears. Of 68 samples submitted from sick dogs, 32 had high echinocyte numbers. Two diseases, glomerulonephritis and lymphosarcoma, accounted for 15 of the 32 cases. In only four instances were echinocytes reported from blood smear evaluation and not found to be high by quantitative studies. We conclude that nonartifactual echinocytosis occurs in the dog and that it may be associated with specific disease

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00556.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00557.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY

ISSN:0275-6382    

DOI:10.1111/j.1939-165X.1990.tb00558.x

出版商:Blackwell Publishing Ltd    

年代:1990

数据来源: WILEY