摘要:

SUMMARYWhen transplanting the ITB tumor by means of ascitic fluid, in which the number of tumor cells was small at first in comparison with that of inflammatory cells, the number of the tumor cells contained in the ascitic fluid rose gradually during the process of transplantation until, from the seventh generation onwards, the neoplasm began to grow in the way typical of ascites tumors.The developed ITB ascites tumor has now been transferred through 100 generations. The rate of successful transplantation has been 82 per cent. The properties of growth, the morphology of the tumor cells in the ascitic fluid, and the histological features of the solid tumor infiltration have remained unchanged during the process of transplantation.Inoculation of tumor cells produced an initial polymorphonuclear response in the peritoneal cavity followed by proliferation of mononuclear inflammatory cells. The tumor cells began to increase greatly in number after the second day, until on the sixth the ascitic fluid was an almost pure culture of tumor cells. Regressive changes were seen in the tumor cell proliferation soon after this, the relative number of the tumor cells showing a remarkable fall during the terminal phase of tumor development.In connection with the ITB ascites tumor there is solid tumor growth in the peritoneal cavity which is very abundant during the terminal phase. Infiltration of the omentum by tumor cells begins 2–3 days after inoculatio

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03156.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYThe Laboratory for Pathology of the Norwegian Radium Hospital has material for the period 1939–1954 comprising 1784 partially or totally gastrectomized stomachs with malignant tumors. Among these there are 21 cases, or 1.2 per cent, which are a distinct tumor type interpreted as hemangioendotheliomas. They are sufficiently well characterized pathologically to be diagnosed. The tumors exhibit a very moderate malignancy with a good prognosis. The pathology of these tumors, particularly their macroscopic features, histology and differential diagnostics are discussed, and the results of follow‐up examinations are presen

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03157.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYUrinary bladders from fully developed fetuses of rabbit and slips of skin from newborn rabbits, aged 6 hours, were placed in a 1 per cent trypan blue solution from George T. Gurr (No. 06186) for about 24 hours in ordinary room temperature. They were then transferred to the hypodermis of grown‐up rabbit males. The transplants and their surroundings were microscopically examined after 14 days (the urinary‐bladders) and 21 days (the skin). The control material consisted of an identical number of transplantations of the same organ without any foregoing staining (called “direct” transfers).Healthy transitional epithelium round cysts of a varying size appeared in the trypan blue group at a frequency so markedly higher that the conclusion is drawn that trypan blue treatment causes a prolongation of the survival time of that epithelium.Epithelium of an epidermal character appeared definitely in 4 cases of skin transfer after trypan blue treatment, but in no instance among the controls (18 transfers in each group).It is stated as probable that the epithelium that was found had been formed through proliferation from regenerative centres within the transferred epithelium, while the epithelium otherwise has been lost. Possibly, the trypan blue treatment, it is also suggested, has increased the vitality in the regenerative centres.Before work on the above lines is continued, it is, however, indispensable to try to find the answers to some other questions regarding the mechanism of the trypan blue treatment, as propounded in the intro

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03158.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYFollowing childbirths and transfusions of Jk (a+) blood a woman of type Jk (a—–) developed anti‐Jka. Her serum has been used to investigate the Kidd blood group distribution in Norway. Examination of mother‐child combinations and family material confirm the theory of inheritance of the factor Jka as earlier de

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03159.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYAfter a survey of the literature the author reports 4 new cases of gastric carcinoma and 10 of intestinal carcinoma in the dog. In the discussion the data of all known cases of gastro‐intestinal carcinoma are analysed with regard to frequency, age, sex ratio, the site of the tumours in the stomach and intestine, the type of carcinoma, their relationship to ulcers and chronic inflammation and their metastasising dispositio

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03160.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYWhite mice of a homologous strain were exposed to total‐body x‐irradiation, the dose ranging from 600 to 750 r. They were treated for varying periods with streptomycin alone, RES—(reticuloendothelial system)—stimulating substances, or a combination of these two media. All the substances were administered with the micro‐injection technique.Streptomycin alone in a dose of 1000 gamma per animal per day is found to have some effect against bacterial infections. RES‐stimulating substances alone or in combination with streptomycin do not give uniform results. The experimental conditions in this type of experiment ar

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03161.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYA newSalmonellaO subgroup: (9), 46 is described, including the following types:S. strasbourg= (9), 46: d:1, 7 andS. haarlem= (9), 46:z:e,n,x.

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03162.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYNine Salmonella types have been isolated from tortoises. Eight of them belong to types which have previously been identified. One is a new type designedS. solna, with the antigenic formula 28: a: 1,5. I am greatly indebted to dr.F. Kauffmannfor valuable help and confirmation ofS. solna'santigenic formula.

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03163.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY

摘要:

SUMMARYThree typhoid vaccines were tested: an alcohol‐killed and alcohol‐preserved, a heat‐killed and phenol‐preserved, and a formalin‐killed and phenol‐preserved. The antibody‐stimulating properties of the vaccines were determined 1 month after the preparation and after storage for on an average nearly 2 years in the refrigerator.The antibody production was determined by means of Vi and O agglutination tests on immune rabbit sera.If the results achieved with different vaccine preparations are put together it was shown that fresh heat‐killed and formalin‐killed phenol‐preserved vaccines gave a significantly higher Vi antibody production than vaccines stored for on an average 21 months. Alcohol‐killed and alcohol‐preserved vaccine had lost none of its Vi antibody‐stimulating property after storage.The O‐antibody‐stimulating property was impaired only for the formalin‐killed and phenol‐preserved vaccine after storage.By the method of immunization employed we could expect demonstrable impairment of the O antibody stimulation o

ISSN:0365-5555    

DOI:10.1111/j.1699-0463.1956.tb03164.x

出版商:Blackwell Publishing Ltd    

年代:1956

数据来源: WILEY