摘要:

A novel polyhydroxylated epoxy steroid (1) has been isolated from the soft coral Sinularia dissecta and characterized by the study of spectral data.

ISSN:1057-5634    

DOI:10.1080/10575639908048790

出版商:Taylor & Francis Group    

年代:1999

数据来源: Taylor

摘要:

Tissue lines, selected from explants ofTabernanthe ibogaH. Bn. and cultured in shake flasks, produced and released from three to five indole alkaloids into the culture medium. the iboga alkaloids in order of their relative abundance were ibogaine, dihydroxyibogamine, ibogamine, voacangine, and ibogaline. All five compounds have the same basic ring structure as ibogaine, a putative anti-addictive drug. Three of these could consistently be detected in culture medium that was removed and replaced at two-week intervals over periods of at least five months. the nutrient-hormone combination used consisted of Gamborg's B5 medium with 2% w/v sucrose, 2mg/l 2,4-dichlorophenoxy-acetic acid (2,4-D) and 0.1 mg/16-benzyladenine (BA). These results suggest that plant tissue culture procedures can be developed as an economically feasible and environmentally responsible source of ibogaine and other potential anti-addictive drugs.

ISSN:1057-5634    

DOI:10.1080/10575639908048791

出版商:Taylor & Francis Group    

年代:1999

数据来源: Taylor

摘要:

This is a scanned image of the original Editorial Board page(s) for this issue.

ISSN:1057-5634    

DOI:10.1080/10575639908048779

出版商:Taylor & Francis Group    

年代:1999

数据来源: Taylor