摘要:

Two new alkaloids, 17-desoxy-cfs-lamprolobine (1) and bonzakaline (2), along with the known alkaloids lupanine (3) and palmatrubine (4), have been isolated from the ethanolic extracts ofBongardia chrysogonum.Compounds1and2have shown antibacterial activity againstProteus mirabilis, Proteus vulgaris, Klebsiella pneumoniae, Escherichia coliandShigella dysenteriae.the structure elucidation was performed by using various spectroscopic methods including 2D NMR techniques1,2.

ISSN:1057-5634    

DOI:10.1080/10575639808048287

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

Insecticidal lignans gomisin B and gomisin N were isolated from then-hexane extract of fruits ofSchisandra chinensisunder bioassay guide ofDrosophila melanogasterMeigen. Gomisin B and N showed the lethal dose for 50% mortality(LC50) at concentration of 0.031μmol/ml and 0.125μmol/ml, respectrively.

ISSN:1057-5634    

DOI:10.1080/10575639808048288

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

The revision of trinervinol (1) structure, a tricyclic diterpene isolated fromPiqueria trinervia cav., led to the modification of the double bond position as well as to the inversion of configuration at glycol and possible hydroxymethylene moieties bearing asymetric carbons. the study was done using 1D and 2D high-resolution NMR.

ISSN:1057-5634    

DOI:10.1080/10575639808048289

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

The new 3′,6,8-trichloro-4′,5-dihydroxy-7-methoxyisoflavone (1) and 3′,5′, 6,8-tetrachloro-4′,5-dihydroxy-7-methoxyisoflavone (2) have been isolated from the wood ofOuratea semiserrateMart. (Engl.). Their structures were established from spectroscopic data, including 2D NMR experimetns and mass spectra.

ISSN:1057-5634    

DOI:10.1080/10575639808048290

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

The molecular basis of β-thalassaemia in two linguistically and ethnically different groups of Pakistan was studied. These groups were the Potwari Punjabis residing in the Potwar region of North West Punjab and the Pathans residing in the North West Frontier Province (N.W.F.P.). A combination of amplification-refractory mutation system-polymerase chain reaction (ARMS-PCR) and DNA sequencing was used to screen for mutations in the β-globin gene of patients and carriers. In the Punjabis three mutations; IVS-1 position 5 (G-C), codons 8/9 (+G) and codons 41/42 (-CTTT) account for 82.2% of the total characterized alleles. In this groups the rare mutations, found at 17.8% of the total characterized alleles, are capsite +1 (A-C), codon 16 (-C), codon 5 (-CT), the 619 bp deletion at the 3′ end of the gene, IVS-2 position 1 (G-A) and codon 30 (G-C). In the Pathans four mutations; codons 8/9 (+G), IVS-1 position 5 (G-C), codon 5 (-CT) and codons 41/42 (-CTTT) account for 82.4% of the total characterized alleles. the rare mutations in this group account for 17.5% of the total characterized alleles and are codon 15 (G-A), codon 16 (-C), capsite +1 (A-C), IVS-1 position 1 (G-T), codon 30 (G-A), IVS-1 position 1 (G-A), codon 30 (G-C) and codon 6 (A-T). the mutation spectrum reproted in this study differs from that reported previously by Ahmedet al.(1997, British Journal of Haematology,94, 476–482) in Punjabis and Pathans. the differences in the mutation spectrum of the β-globin gene in thalassaemia patients and carriers in the Potwari Punjabis and the Pathans reported in the present study emphasizes the importance of determining and classifying accurately the ethnic history of the subjects and the mutations present in each ethnic group within a country separately.

ISSN:1057-5634    

DOI:10.1080/10575639808048291

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

5-Bromoverongamine (2), a novel antifouling tyrosine alkaloid has been isolated together with 5-oxo-5,6,7,8-tetrahydroimidazo[1,5-c]pyrimidine (1) from a Caribbean Sea specimen of the marine spongePseudoceratinasp. Its structure was determined on the basis of its spectral properties.

ISSN:1057-5634    

DOI:10.1080/10575639808048292

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

The microbial transformation of vindoline (1) byAspergillus niger, Fusarium liniandF. monolinumafforded 17-deacetylvindoline (2) as the sole metabolic product, whereas α-santonin (3) was regiospecifically reduced to 1,2-dihydro-α-santonin (4) byAspergillus niger.

ISSN:1057-5634    

DOI:10.1080/10575639808048293

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

3-Oxo-lanosta-20-25-diene-3-one (1), a new lanostan-type triterpene along with a new alkaloid methylisoplatydesmine (2) have been isolated from the aerial parts ofSkimmia laureola. the structures of these compounds were determined by spectral studies.

ISSN:1057-5634    

DOI:10.1080/10575639808048294

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

Cunningamella echinulatacultures monohydroxylate ilicic acid at C-1 and C-2cisto the methyl groups at C-4 and C-10.

ISSN:1057-5634    

DOI:10.1080/10575639808048295

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor

摘要:

A new macrocyclic diterpene, esulol A (1), was isolated from the aerial parts of ChineseEuphorbia esulaL. (Euphorbiaceae). the relative structure was elucidated by spectroscopic analyses as a novel highly oxygenated jatrophane derivative.

ISSN:1057-5634    

DOI:10.1080/10575639808048296

出版商:Taylor & Francis Group    

年代:1998

数据来源: Taylor