摘要:

A new natural product, amabiloside (1, i.e. 3-hydroxy-4-O-β-D-glucopyranosyl-benzaldehyde) was isolated from the bulbs ofCrinum amabileDonn. Its structural characterization and unequivocal1H and13C NMR assignments were achieved through analysis of the COSY, NOESY, HETCOR, and selective INEPT spectra. Amabiloside (1) was evaluated for its cytotoxic and antimalarial potential, but was found to be inactive. 1 was previously known only as a synthetic.

ISSN:1057-5634    

DOI:10.1080/10575639308043830

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

The spectral properties oftrans-capsaicin, the principal pungent ingredient in manyCapsicumspecies and varieties, and its syntheticcis-isomer were assigned unambiguously by a combination of COSY, HMQC, and HMBC NMR techniques.

ISSN:1057-5634    

DOI:10.1080/10575639308043831

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

The effect of different auxins (2,4-D, 2,4,5-T, NAA and IAA) on calli maintenance and plant cell suspension initiation as well as the influence of auxins in combination with citoquinines on growth and solasodine productivity by cell suspensions ofSolanum eleagnifoliumCav. was studied. 2,4-D and 2,4,5-T produced a friable and productive calli line and a fine and homogeneous cell suspension cultures. 2,4-D (0.5 μM or 5 μM) or NAA (50 μM) produced the highest growth index and solasodine productivity with values of about 0.5 mg 1−1day−1to 0.8 mg 1−1day−1. Simultaneous administration of auxin and cytokinin increased the solasodine productivity with a diminution of cell growth. The combination of NAA (50 μM) with kinetin (0.25 μM) produced an increase of solasodine productivity from 0.8 mg 1−1day−1to 2.54 mg 1−1day−1. An inoculum size of 5% V/V and 19-day-old was selected to be used in fermentation processes in order to obtain solasodine production byS. eleagnifoliumCav. suspension cultures. Processes carried out in erlenmeyer flasks and stirred tank reactors byS. eleagnifoliumCav. suspension cultures showed similar specific growth rates (0.16 day−1and 0.19 day−1respectively) and maximal solasodine yields (0.91 mg g−1to 1.05 mg g−1respectively) but they presented differences in the maximal biomass value obtained (3.9 g DW 1−1in erlenmeyer and 5.2 g DW 1−1in bioreactor).

ISSN:1057-5634    

DOI:10.1080/10575639308043832

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

Three new guaianolides, 11-H-13-methylsulfonylgrosheimin (5) (grosulfeimin), 8-deoxy-11, 13-dihydroxygrosheimin (7) and 8-deoxy-11-hydroxy-13-chlorogrosheimin (8) have been isolated from the leaves ofCynara scolymusL. Furthermore, the already known 8-epigrosheimin (9) has been isolated for the first time from this source. The structures were determined by both spectroscopical methods and chemical correlations.

ISSN:1057-5634    

DOI:10.1080/10575639308043833

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

A new ichthyotoxic 1,2-sn-diacylglycerol having tiglic and clerodane acid-derived acyl moieties has been isolated from the mantle of the dorid nudibranchArchidoris pseudoargusand its structure established by spectroscopic and chemical means.

ISSN:1057-5634    

DOI:10.1080/10575639308043834

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

Six cell suspension cultures established from different organs ofThevetia peruvianawere initiated under various growth conditions. Even after two years of subculture, cardenolides proved to be present in all the strains. The cardenolide content varied from one strain to another according to the nature of the original explant and was always lower in comparison with that of the seeds of the original plant. Kinetic studies showed that the cardenolide content varied over a complete cycle of culture.

ISSN:1057-5634    

DOI:10.1080/10575639308043835

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

A novel cyclic metabolite named amarulone (1) was isolated fromPhyllanthus amarusand its structure was elucidated by spectra analysis of its phenazine derivative (2).

ISSN:1057-5634    

DOI:10.1080/10575639308043836

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

From the stem bark ofMesua ferreabetulinic acid, (-)-epicatechin, 1,6-dihydroxyxanthone, pyranojacareubin and two novelbis-xanthones have been isolated. Thebis-xanthones were characterised, on the basis of 2D homo- and heteronuclear correlation NMR spectroscopy as (E)-2ξ-methyl-2ξ-{2-(2,7,9-trihydroxyxanthon-8-yl)ethen}-dioxan-({5,6c:2,3e-}-7-hydroxy-4,9-dimethoxyxanthone) (mesuabixanthone-A) and its monomethyl ether (E)-2ξ-methyl-2ξ-{2-(7,9-dihydroxy-2-methoxyxanthon-8-yl)ethen}-dioxan-({5,6c:2,3e}-7-hydroxy-4,9-dimethoxyxanthone) (mesuabixanthone-B).

ISSN:1057-5634    

DOI:10.1080/10575639308043837

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

Three metabolites have been isolated from the aerial parts ofPoliothrysis sinensis. One of these was the known compound poliothrysoside 2-(6-O-benzoyl-β-D-glucopyranosyloxy)-5-hydroxybenzyl alcohol. The other two compounds are novel cyclohexenone derivatives of poliothrysoside and have been given the trivial names poliothrysin 2-β-D-glucopyranosyloxy-5-hydroxybenzyl-1-hydroxy-2-oxo-5-cyclohexene carboxylate and poliothrysin benzoate 2-(6-O-benzoyl-β-D-glucopyranosyloxy)-5-hydroxybenzyl-1-hydroxy-2-oxo-5-cyclohexene carboxylate.

ISSN:1057-5634    

DOI:10.1080/10575639308043838

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor

摘要:

The carbon chemical shifts of the ethylenic carbon atoms of methyl ricinoleate (12-hydroxy-9-cis-octadecenoate) are 133.32, C-9; 125.28, C-10 and those of methyl ricinelaidate (12-hydroxy-9-trans-octadecenoate) are 134.56, C-9 and 125.97, C-10. The shift values were confirmed by double irradiation (spin decoupling) and1H-13C COSY nuclear magnetic resonance techique.

ISSN:1057-5634    

DOI:10.1080/10575639308043839

出版商:Taylor & Francis Group    

年代:1993

数据来源: Taylor