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| 21. |
A Rapid Analysis of Nafcillin Using High‐Performance Liquid Chromatography |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 105-108
Patty,
Fan-Havard Milap,
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摘要:
A simple, rapid, and reproducible high-performance liquid chromatography method is described for the measurement of nafcillin using an internal standard (IS), 5-(p-hydroxyphenyl)-5-phenylhydantoin. A one-step protein precipitation was used for preparation of nafcillin and IS. The mobile phase included 0.02Mammonium acetate buffered solution and acetonitrile (75:25 vol/vol). An Ultrasphere ODS reversed-phase column was used and the detector was set at 224 nm. The retention time of IS and nafcillin was 4.8 and 6.6 min, respectively. The absolute recovery for nafcillin ranged from 95–98%. The intraday coefficient of variation for the assay was 3.5% at nafcillin concentrations of 1.0 and 60 mUg/ml. The interday coefficient of variation was 7.1 and 3.1% at the nafcillin concentrations of 1.0 and 60.0 mUg/ml, respectively. The major advantages of this method include the single-step extraction and the use of a small volume (50 mUl) of serum samples for nafcillin measurement. The serum concentrations of nafcillin in a pediatric patient were determined to demonstrate the application of this method.
ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 22. |
Interpretation of Excessive Levels of Inhaled Tobramycin |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 109-110
Yedidia,
Bentur David,
Hummel Chaim,
Roifman Esther,
Giesbrecht Gideon,
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 23. |
A Useful Microscale Method for Monitoring Furosemide by High‐Performance Liquid Chromatography? |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 111-111
Bruce,
Charles Peter,
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PDF (168KB)
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 24. |
A Reply to Charles and Ravenscroft |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 112-112
S.,
Sood Victor,
Green Zola,
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 25. |
Interference of Spironolactone Metabolites in a Digoxin Radioimmunoassay |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 113-113
D.,
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 26. |
A Reply to Crothers |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 114-114
Raymond,
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 27. |
Antimicrobial Therapy in Infants and Children |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 115-116
Godeon,
Koren Charles,
Prober Marcel,
Dekker Margaret,
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 28. |
Endocrinology of Aging |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 117-117
James,
Sowers James,
Felicetta Manjula,
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PDF (183KB)
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 29. |
Problems in Pediatric Drug TherapySecond Edition |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 118-118
Louis,
Pagliaro Ann,
Pagliaro Jo,
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PDF (93KB)
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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| 30. |
Erratum |
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Therapeutic Drug Monitoring,
Volume 11,
Issue 1,
1989,
Page 119-119
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ISSN:0163-4356
出版商:OVID
年代:1989
数据来源: OVID
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