摘要:

SYNOPSIS82 adolescent or adult patients in whom the diagnosis of basilar artery migraine (BAM) had been made or suspected were reviewed. When rigorous criteria were used, the diagnosis could be confirmed in 49 patients (32 women and 17 men). Seven other patients probably had BAM, but did not totally fulfill the criteria. In 26 cases reevaluation did not confirm the diagnosis.In the 49 patients with definite BAM the age of onset ranged from 10 to 62 years, 65% of them having their first attack in the second or third decade. 40% had BAM attacks only, while 60% had additionally other types of migraine attacks. A typical pattern of attacks with an “ischemic” aura followed by predominantly occipital headache was found in only 57%. The most frequent “ischemic” symptom was bilateral visual impairment (86%). Symptoms and signs of brain stem dysfunction were vertigo (63%), gait ataxia (63%), bilateral paresthesia (61%), bilateral weakness (57%), and dysarthria (57%). 77% of the cases had disorders of consciousness (mainly syncope, confusion and prolonged amnesia). 4 patients (8%) had epileptic seizures during the migraine attacks. 73% had a family history of migraine and 12% of epilepsy. EEG's were always abnormal during the attacks with predominantly localized or generalized mostly paroxysmal slow wave activity. CT scans were normal except for 2 women with repeated BAM attacks, who were smokers and taking contraceptive drugs, and who during an attack experienced a cerebellar and an occipital lobe infarction respectively. Of the 26 patients in whom the diagnosis of BAM could not be confirmed 13 had other types of migraine, while the remaining cases had temporal lobe epilepsy, intermittent vertebral basilar artery insufficiency, orthostatic hypotension or hysterical

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508408.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISMigraine symptoms were assessed in a sample of about 2300 school children between 10 and 17 years of age in Amsterdam. Prevalence of migraine symptoms was very similar to that reported by Waters using the same questionnaire. Headache intensity gave a reliable indication of the presence of other migraine symptoms. This finding was crossvalidated in several subsamples and confirmed the severity hypothesis of Waters for a young population.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508416.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISWhile headache represents one of the most common medical complaints of children, very little is known about its phenomenology. In the two studies currently reported, children's headache complaints were assessed in several ways. In Study 1, 53 children and their parents provided estimates of 3 parameters of headache during separate interviews and then engaged in 4 continuous weeks of daily record keeping, all of which occurred prior to participating in a behavioral treatment program. In Study 2, 37 of the children who had completed treatment and their parents participated in the same type of assessment to determine correspondence between various ways to gauge improvement. Additional estimates of improvement were collected by administering visual analog scales to children, parents, and a pediatric neurologist (upon completion of his independent interview). Although child and parent estimates of headache activity obtained at the initial interview were highly consistent, these estimates greatly overstated the values recorded by the children in their daily diaries. Interview estimates overstated diary values by from 56% to 112%. The interview estimation biases were greatly reduced by treatment's end, however, and were no longer significant for all but 1 measure. Parent and child diaries revealed high levels of agreement for headache intensity both prior to and following treatment. Signficant disagreement occurred prior to treatment for headache frequency, but this did not continue following completion of treatment. Visual analog estimates of improvement were not statistically different from improvement measured by diary report, although children, parents, and neurologist underestimated actual improvement by 5%, 10%, and 20%, respectively.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508421.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISWe describe a 61‐year‐old woman with unilateral ophthalmoplegia with migraine type headache. Pathological examination revealed severe atrophy of the third cranial nerve as the result of vascular compression by the atheromatous posterior cerebral artery. Although the exact pathogenesis of ophthalmoplegic migraine (OM) is uncertain at the present time, this unique case with clinical and pathological observations suggests that vascular compression and the resulting ischemia of the third cranial nerve can closely simulate

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508426.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISThe authors describe three female patients, ages 30, 23 and 18, with migraine and cerebral infarction, selected from a series of 51 young patients with stroke. All of them were submitted to an extensive clinical and laboratory protocol that included angiography and computer tomography (C.T.), in order to exclude other etiologies for cerebral infarction (C.I.). All patients had episodes of hemispheric cerebral ischemia or infarction and the C.T. scan showed cerebral infarction in each case. The angiograms were normal (except in the first case which showed a transient spasm of the extracranial internal carotid arteries). The first patient has a residual motor deficit but the others recovered completely in a few days. The data analysis suggest a close relationship between migraine and cerebral infarction in our three cases.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508429.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISThe platelet theory of migraine causation predicts that drugs inhibiting platelet activation will be effective in migraine prevention, but the literature indicates that this is only partly the case. Conversely, therapy achieving clinical benefit should be associated with reduced platelet activity. To test this concept, the β‐adrenergic blockers propranolol (non‐selective), metoprolol (β1‐selective) and Li‐32468 (β2‐selective) were used in migraine therapy with assessments of platelet aggregation and release, plasma thromboxane A2(measured as thromboxane B2) and clinical response.Between propranolol and Li‐32468, there was lack of correlation of clinical with platelet effects. Propranolol and metoprolol, whose established efficacy in migraine prophylaxis was reflected here, actually had opposite effects on platelet activity, which was increased with the former and inhibited by the latter. Yet both drugs gave elevated thromboxane B2levels.In view of this complete dissociation between drug effects on platelets of migraineurs and symptoms of migraine, the platelet theory of migraine causatio

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508434.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISPatients presenting migraine headache associated with Raynaud's disease have been successfully treated in our clinic by using peripheral skin temperature biofeedback (BFB). The diagnosis of primary headache was established in all patients many years before Raynaud's disease appeared.We selected 15 females for this study. Subjects were taken off all medication and patients' motivation for feedback therapy was ascertained. The time sequence of the peripheral skin temperature BFB sessions was the same as the one commonly followed at the Biofeedback Unit of the University of Rome Headache Service, i.e., two sessions per week in the first month of training, one session per week in the second, and subsequently one session every two weeks for four months, The use of a Headache Rating Scale for clinically evaluating BFB treatment for the relief of migraine attacks produced objective and comparable data suitable for statistical analyses, just as did the results of cold pressor tests studied before and after BFB training for evaluating the Raynaud's disease improvement.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508441.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

摘要:

SYNOPSISThe Dzidra Glass is a battery powered, self‐contained eyeglass using two liquid crystals to cast shadows on the closed or open eyelids at a rate of 1 to 3 hz. They are designed to induce relaxation through slow wave photic stimulation with one to five minutes of use, without concomitant medications or prior relaxation training. This study reports the preliminary experience with this modality in the treatment of headache.Fifteen patients with acute muscle‐contraction type headache, six patients with chronic muscle‐contraction type headache, three patients with headache associated with acute sinusitis, and four patients with migraine were treated with the Dzidra glasses for five minutes. Fourteen of fifteen patients with acute muscle‐contraction type headache and five of six patients with chronic muscle‐contraction type headache and five of six patients with chronic muscle‐contraction type headache noted complete relief after treatment. One patient with chronic muscle contraction type headache and all patients' with headache associated with acute sinusitis and migraine headache noted no relief after treatment. Four patients with acute muscle‐contraction type headache were treated in a placebo‐controlled trial. None of the four responded to placebo, but all responded to treatment with slow wave photic stimulation.We conclude that in this preliminary report, slow wave photic stimulation appears to be effective in the treatment of acute and chronic muscle‐contract

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508444.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1985.hed2508447.x

出版商:Blackwell Science Inc    

年代:1985

数据来源: WILEY