摘要:

SYNOPSISAn experiment is described which compared visual evoked potential (VEP) amplitudes and latencies in normal subjects and migraine patients. Several VEP abnormalities were found: at vertex and to a lesser extent at temporal sites, P100‐N120 amplitudes were larger in patients; at vertex and temporal sites N120 amplitudes were larger in patients; at temporal sites patients had larger N120‐P200 amplitudes but smaller P100 amplitudes. Peak latencies of the VEP were also found to be abnormal in patients. At vertex, patients had delayed N120 peak latencies while at temporal sites delays were found in the P200 latencies. Patients were subdivided according to side of headache. Right‐sided headache patients showed larger temporal P100 amplitudes and larger left temporal P100‐N120 amplitudes than bilateral headache p

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302049.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISChocolate, cheese and citrus fruit are the most frequently cited provoking factors to which patients ascribe their dietary migraine. We review here the evidence that the monoamines they contain, particularly tyramine, might be causative and conclude that the case remains open. There is no evidence that patients classifiable within this particular subgroup of the disease have a deficiency of the monoamine metabolizing enzyme, monoamine oxidase.We report the new finding that dietary migraine patients have a relative deficiency of the enzyme, phenolsulphotransferase P, compared with non‐dietary migraine patients or controls. Phenolsulphotransferase is particularly active in the intestine where it probably serves to detoxify phenols by adding to them a sulphate group. The enzyme exists in two forms, which we have designated M and P. The M enzyme acts on monoamine phenols such as noradrenaline and tyramine. It is also somewhat reduced in dietary migraine but less significantly so than the P form. No endogenous substrate for the P enzyme has yet been identified but it acts on phenol itself and presumably also on a range of unknown phenols in chocolate, cheese and citrus fruit which are important "triggers" for dietary migrain

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302053.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISProstaglandin E2(PG‐E2) levels were measured in the saliva of 6 women suffering from common migraine, during an attack, and in the interval between attacks; the results obtained were compared to the levels found in a matched control group of healthy women. There was a significant increase in the levels of PG‐E2during migraine attack P<0.05. These results may suggest that PG‐E2takes an important role in the mechanism of mig

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302059.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISA total of 193 migraineurs underwent a medical screening for entry into a controlled, experimental migraine study. An isotope brain scan or a CT‐Scan, EEG, skull X‐ray, and laboratory tests, as well as a complete physical examination, were routinely done on each subject. Tests results were examined as to clinical usefulness in the screening for headache. It is the authors' conclusion that a CT‐Scan is the most effective screening test and, in most cases, the isotope brain scan, EEG, and skull X‐ray can be eli

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302062.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISIn a controlled trial the effect of traditional Chinese acupuncture versus placebo acupuncture was evaluated in 16 patients with chronic facial pain (13 atypical facial pain, 2 atypical and I typical trigeminal neuralgia). All patients suffered from daily pain, the intensity of which was recorded by the patients over a period of 16 weeks. Each patient was treated by traditional Chinese acupuncture as well as placebo acupuncture in a cross‐over design following randomization. Each period of treatment comprised 10 treatments during two weeks of hospitalization.Traditional Chinese acupuncture was found to be significantly more pain‐relieving than placebo acupuncture according to the pain registration of the patients themselves and to their subjective preferen

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302066.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISThe postulated pivotal role of focal brain hypoxia in the genesis of the migraine attack and the anti‐hypoxic properties of flunarizine, have led to the use of the selective calcium‐entry blocker in the treatment of migraine. Clinical experience is reviewed. Open findings, confirmed by double‐blind placebo‐controlled studies and comparisons with pizotifen and cinnarizine, have shown that flunarizine, given at 10 mg daily, is a safe and effective prophylactic drug for both common and classical migraine. Factors determining the efficacy of flunarizine are di

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302070.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISThree headache specialists independently evaluated one hundred and fifty patient headache histories and classified them into separate diagnostic categories. Personality data from selected scales of the MMPI and frontalis electromyographic readings during three stimulus conditions were compared between migraine patients and combination headache patients. Patients were also asked to rate the perceived level of stress elicited by the three conditions (sitting comfortably at rest, performing mental arithmetic, and imagining a severe headache).Results indicated that raters could reliably classify patients into the migraine or combination headache group, as well as differentiate either of those groups from other headache diagnoses. Subjects in the combination group had higher MMPI scores on scale one (hypochondriasis), scale two (depression), scale three (hysteria), and scale seven (psychasthenia). There was no significant difference in frontalis muscle tension between the two groups although both showed a significant amount of muscular reactivity to the stress induction conditions. Subjects were accurate in their perception of this reactivity. Methodological suggestions were made regarding future phychophysiological research with headache patients.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302075.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISForty, daily headache patients were divided into two diagnostic categories ‐ chronic scalp muscle contraction headache alone and chronic scalp muscle contraction headache associated with analgesic rebound. Electromyographic readings from the frontalis muscle and personality data from selected scales of the MMPI served as comparison variables between the two groups.A second part of the study divided these headache patients into a high muscle tension group (the ten patients with the highest frontalis muscle readings) and a low muscle tension group (the ten patients with the lowest frontalis reading). This division was made regardless of the original group membership. Personality data in these two groups were compared.Results provided information regarding the relationship between the amount of medication taken by the patient, their degree of psychopathology as measured by the MMPI, and the amount of muscle tension recorded. Suggestions for future research projects were mad

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302083.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

摘要:

SYNOPSISMuscle contraction headache is believed to result from sustained contraction of muscles involving the neck, scalp, and frontalis musculature. This study stresses the clinical importance of examining neck muscle activity in 16 subjects. Two questions are addressed: (1) Do subjects who in the process of treatment for headaches originating from the neck and who received EMG feedback from frontalis and neck musculature select the neck feedback site as more useful in the control of headache? (2) Is frontalis activity as measured by the EMG a measure of the level of activity in other portions of the skeletal system, namely neck musculature? Results indicate that neck involvement varies significantly among patients complaining of chronic muscle contraction headaches, and that a substantial number of subjects experience far more neck than frontalis activity and benefit from behavioral techniques applied to that area. Our findings indicate that attending specifically to neck tissue is a useful therapeutic goal. Consequently, post‐treatment results show significant reductions in neck tissue muscle activity, especially for patients reporting significant neck symptomatology and/or those with high levels of EMG neck activity who reported that behavioral techniques applied to the neck area were helpful for controlling the muscle activity related to their headache

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302086.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1983.hed2302091.x

出版商:Blackwell Science Inc    

年代:1983

数据来源: WILEY