摘要:

SYNOPSISHeadache is the most common side effect of nitroglycerin, administered for angina pectoris. Two phases can be distinguished innitroglycerin‐inducedheadache: the first phase (immediate headache), a mild sensation of temporal pulsating pain, can be due, at least in part, to the vasodilation provoked by nitroglycerin; the second phase (delayed headache), an increasing pain, possibly with nausea and vomiting, lasting even for a number of hours, isindependentfrom the vasomotility, since it arises and persists when all vasomotor and metabolic nitroglycerin‐induced changes are over. The present investigation demonstrates that healthy subjects, neither suffering from idiopathic headache nor with a family headache history, never complain of delayed headache afternitroglycerin; healthy subjects not suffering from headache but who have one or both parents suffering from migraine, exhibit the delayed long‐lasting headache in 28.6% of cases; finally, 66.7% of their migrainous parents complain of the delayed long‐lasting headache after nitroglycerin. The following conclusions can be drawn: nitroglycerin‐induced delayed headache 1) is not a true side effect of nitroglycerin, since it is never present in healthy subjects; 2) is peculiar to migraine sufferers: or 3) is an index of migraine predisposition, as it may be present in healthy subjects, but only if they have one or two migrainous parents. The features of nitroglycerin‐induced delayed headache suggest an analogy with the phenomenon of overreaction, a painful and exaggerated response (in latency, intensity and duration) to a stimulus, that is the most typical aspect of central pain. In nitroglycerin‐induced delayed headache, which shows close similarities to the spontaneous attack of migraine, the trigger stimulus could be the moderate immediate headache which is probably correlated with the vasodilation provoked by

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704180.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISThe response of 25 chronic myofascial head and neck pain patients to a systematic musculoskeletal rehabilitation program was examined. The program emphasized the acquisition of self‐management skills through a highly structured interdisciplinary format. Physical and cognitive behavioral therapies were aimed at reducing factors which perpetuate myofascial pain. Results immediately following treatment, and at three, six and twelvemonths post‐treatment when compared to pretreatment scores, showed highly reliable reductions in self‐reports of pain and medication i

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704186.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISInformation on trigger factors provoking a migraine attack, was collected in 217 migraineurs (176 women, 41 men). In this selected group of patients, most patients were spontaneously aware of one or more trigger factors; 184 (85%) of the patients reported trigger factors with a median number of 3 different trigger factors. The main trigger factors were menstruation (48%) or ovulation (8.5%) in women, certain food (44.7%), alcoholic beverages (51.6%) and stress 148.8%). After excluding the menstrual cycle as a trigger factor, trigger factors were more frequent in women, in older patients and in patients with a longer duration of disease. Women with a menstrual cycle‐related migraine reported more trigger factors, other than the menstrual cycle itself, than women in whom the menstrual cycle had no influence on this migraine: this was especially so for food and beverages. The number and type of trigger factors in the women in whom the migraine was not menstrual cycle‐related, were fully comparable with those in men. Patients in whom alcohol acts as a trigger factor had also significantly more other trigger factors, especially food. The same holds true for patients reporting stress as a trigger factor, but the latter difference is not significant when the different subgroups of trigger factors (food, beverages, other)are considered. Certain trigger factors may be mutually rela

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704191.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISA subgroup of 33 patients were distinguished from 59 other patients with episodic cluster headache by shorterremission periods, specifically of less than six months duration. This subgroup (subchronic cluster headache)was compared to episodic cluster headache patients and an additional 29 patients with chronic cluster headache,for differences in several clinical parameters.Results of this study demonstrated that the subchronic group was clinically similar to the chronic group andsignificantly different from episodic cluster headache patients. Thus, sub‐chronic cluster headache wascharacterized by an increased frequency of treatment‐resistance, headache attacks, drug abuse, hypochondriasisand prolonged cluster periods.Results of this study suggests that subchronic cluster headache, as defined by remission duration of sixmonths or less, may be a clinically relevant class of cluster headache. Distinction of this subgroup from thebroader “episodic” category may permit more accurate prognostic and therapeutic capab

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704197.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISA sustained headache syndrome can develop from headaches of diverse etiologies. Over seven years,112 patients with such a syndrome received 188 sets of injections in the occipital nerve regions andtwo‐thirds had prolonged relief. In such headaches, interrupting the pain cycle with occipital injectionscontaining 1% lidocaine plus betamethasone may be a useful adjunct to other preventive and abortivemedical therapie

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704201.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISThe purpose of this controlled study was to compare anger experience, anger‐relevant psychophysiological parameters, and expressive anger behavior of migraine patients, with those of pain patients and of healthy controls. Based on the probability of solving anagram tasks, we defined an anger‐provoking condition and a control condition. Data from 72 female subjects were used for analysis. Migraine patients showed a deficit in open anger behavior; their diastolic blood pressure decreased and their pulse pressure (SBP‐DBP) was higher compared to the two control groups. They did not differ with respect to their self‐reported anger exp

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704206.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISIn five patients affected by classical migraine a longitudinal study was performed, dealing with thein vitroparameters of platelet aggregation, during prodromal, attack, post‐attack and interval phases. These patterns were compared with the analysis of blood leukotrienes, carried out by use of analytical reversed phase HPLC. Presence of leukotriene C4(LTC4) during prodromal and attack phases, corresponded to a transient inhibition of epinephrine‐induced aggregation. Recovery towards normal or increased values of platelet aggregation occurred during both post‐attack and interval phases, which were accompanied by the presence in blood of 5–12 di‐hydroxyeicosatetraenoic acid (5–12 DHETE) and/or leukotriene B4(LTB4) respectively, and by their subsequent metabolic breakdown products. Hypotheses on the role of leukotrienes in the pathogenesis of migraine ar

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704211.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

摘要:

SYNOPSISThe purpose of the present study was two‐fold. The first was to examine further the prevalence of headache in a college sample. The second was to evaluate the test/re‐test reliability of the questionnaire measure of prevalence and its concurrent validity (by comparing information collected on it to like measures collected by systematic, daily headache diary records). Headache was found to be a widespread phenomenon that was affecting at least 45% of all students once per week, and 35–45% of the students experienced headache severe enough to disrupt planned activities. Headaches experienced by females tended to be more frequent, more intense, and of longer duration. Individual questionnaire items overall evidenced high test/re‐test reliability over 1, 4, and 8 weeks, although responses to inquiries about location and nature of headache pain were varied. However, questionnaire estimates of frequency, duration, and intensity showed little correspondence to data obtained from diary records. In general, questionnaire measures appear to underestimate frequency and duration, while overestimating intensity, when compared to actual recordings of headache activity. Thus, when used in isolation, global questionnaire measures of headache do not appear to provide accurate information about the occurrence of the

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704216.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704224.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1987.hed2704227.x

出版商:Blackwell Science Inc    

年代:1987

数据来源: WILEY