摘要:

SYNOPSISFollowing tooth pulp extirpation, some subjects suffer from persistent pain which affects edentate sitesin absence of any local pathology. As regards this peculiar pain, called phantom tooth pain (PTP), what ispuzzling is the fact there is a low prevalence of PTP in a very large population showing identical conditionsof tooth pulp extirpation. The present investigation indicates that PTP mainly affects migraine (M) andcluster headache (CH) sufferers, whereas it does not affect subjects who have a negative personal andfamily history for idiopathic headache (IH). These results circumscribe the presence of PTP to a specificsection of the population. The present results, besides indicating that PTP may be the result of a peculiarneuronal predisposition relating to IH pathogenesis, suggests some practical therapeutic hints. In fact,successful anti‐ M and anti‐CH prophylactic treatment greatly improve PTP syndr

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109577.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISAn unusual case of an abnormally long‐lasting (over 12 months) visual migraine aura is reported. Theabsence of signs of a structural lesion, as shown by neuro‐imaging and clinical investigations, make difficultthe differential diagnosis between a new variation and a complication of migra

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109582.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISA number of clinical reports have revealed an association between the use of alcohol and drugs and theonset or exacerbation of headaches. In order to investigate this association systematically and to examinethe temporal relationship between onset of headaches and psychoactive substance use, we analyzedresponses to e self‐report questionnaire from 267 consecutive admissions to a three‐week inpatientsubstance abuse treatment program. The response rate was 89.7%. The following characteristics werenoted in the 236 respondents: 1) Over 89% reported having experienced some type of headache. 2)Headache‐free individuals were significantly older than headache sufferers. 3) Women were much morelikely to have migraine headaches than men. 4) Onset of migraines occurred prior to onset of substanceuse, while onset of tension headaches occurred after onset of substance use. Although associational datamust be interpreted with caution, an intriguing hypothesis compatible with the finding is that migrainesmay play a role in the genesis of substance use, while substance use may play a role in the genesis oftension head

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109584.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISTrigeminal neuralgia results from disturbances in the trigeminal root entry zone which generate repetitiveaction potentials. Drugs which relieve the pain of trigeminal neuralgia depress these potentials.Anticonvulsants which exert this or related effects, and which have been demonstrated to be efficacious intrigeminal neuralgia, include carbamazepine, phenytoin, clonazepam, and valproic acid. Baclofen may act byfacilitating segmental inhibition of the trigeminal complex. The mechanism of action of pimozide for treatingtrigeminal neuralgia is not known.Carbamazepine is suggested as the drag of first choice; baclofen or clonazepam could be added ifcarbamazepine monotherapy is ineffective. When these fail, monotherapy with phenytoin, pimozide, or valproicacid would be a reasonable next step.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109588.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISWe measured vascular reactivity ‐ expressed i) as decrease in blood flow velocity (cm/sec) per vol% CO2decrease due to voluntary hyperventilation and ii) as increase of blood flow velocity during the first minuteafter resuming normal ventilation, per vol% CO2 increase ‐ in the middle cerebral and basilar artery of 48migraineurs with attacks without aura, and 17 normal controls. We found no differences for bothdeterminants of vascular reactivity between migraineurs during and outside an attack, and betweenmigraineurs and healthy volunteers. We conclude that the vasomotor reactivity is normal during migraineattacks without a

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109593.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISNitroglycerin, a vasodilating agent, was administered sublingually in migraine without aura patients andin healthy volunteers. Systolic, diastolic and time‐mean flow velocity and pulsatility index, were measuredby transcranial Doppler sonography in the major intracranial arteries before and after nitroglycerinadministration. Following nitroglycerin administration, a significant decrease in systolic and time‐meanvelocity and pulsatility index was observed in migraine patients, whereas in control subjects onlytime‐mean velocity decreased significantly. Based on those findings we hypothesize a more markedresponsiveness to nitroglycerin in migraine patients as compared to healthy sub

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109596.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISAmong our patients with benign intracranial hypertension, we encountered 3 who presented withunusual clinical features. Presentations were pseudotumor without papilledema, unilateral papilledema,and IIIrd and Vth cranial nerve involvement. Lumbo‐peritoneal shunt completely resolved the symptomsand signs in 2 of the patients; in the third, symptoms and signs cleared following lumbar punctur

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109599.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISSeventy‐eight patients with tension‐type headache (TH) were treated with tizanidine hydrochloride(tizanidine). Plasma 3‐methoxy‐4‐hydroxyphenylglycol (MHPG) and serum free fatty acids (FFA) levels in thesepatients were determined before the treatment with tizanidine. Eighteen healthy volunteers composed thecontrol group. Four weeks after the treatment with tizanidine 24 (31%) of 78 patients showed excellentimprovement (excellent group); 28 (35%) showed moderate improvement (moderate group); 18 (23%) showedmild improvement (mild group); 7 (10%) showed no improvement and one (1%) showed worsening of herheadache (no change and worsened group). The plasma MHPG levels in the excellent group were significantlyhigher than in the other groups, including the control group. The serum FFA levels in the excellent group weresignificantly higher than in the controls.In this study, 66% of the patients reported improvement in their headaches. Some patients with TH had highplasma MHPG levels and these patients in particular showed excellent improvement after the administration oftizanidine. Though there may be a placebo response to some extent, the clinical usefulness of tizanidine for THseems to be excellent. Further study is necessary concerning the pharmacological effect of tizanidine andplasma MHPG levels in patient

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109601.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISThe aim of the present study was two‐fold: to assess the long‐term effects of biofeedback on migraine, andto determine the extent to which additional treatment after biofeedback treatment is completed can affectfollow‐up results. Ninety‐six women whose migraine had been treated through biofeedback either 2–3 years(shorter follow‐up) or 6–7 years (longer follow‐up) earlier were divided into four groups according to how longago they had received their biofeedback treatment and whether or not they had received any additionaltreatment (whatever the nature) since the posttreatment assessment: shorter follow‐up without additionaltreatment (n = 24), shorter follow‐up with additional treatment (n = 22), longer follow‐up without additionaltreatment (n = 24), and longer follow‐up with additional treatment (n = 26). Subjects were asked to keep aheadache diary for five weeks, as they had done during earlier assessments, Overall, results showed thatmigraine activity was significantly less at follow‐up than at pretreatment. However, whether the observedlong‐term benefits could be attributed to biofeedback was unclear because medication was found to be asmuch in use at follow‐up as at pretreatment. Results also indicated that 51% of the subjects did seek additionaltreatment between posttreatment and follow‐up. Contrary to expectations, however, additional treatment wasnot associated with better therapeutic benefits at follow‐up. The research and the clinical implicatio

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109605.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY

摘要:

SYNOPSISFlunarizine, a calcium channel blocker is considered useful in migraine prophylaxis. We report the first Indian trial with thisdrug. Fifteen patients with migraine were studied in a 6 months double‐blind, placebo‐controlled crossover trial. Flunarizinewas superior to placebo in reducing the severity and duration of the individual attacks though there was no statisticallysignificant effect on frequency of migraine attacks. The side effects most frequently caused by flunarizine were weight gainand daytime sleepin

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1991.hed3109613.x

出版商:Blackwell Science Inc    

年代:1991

数据来源: WILEY