ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508447.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Purpose.‐Quality of life evaluations can enhance traditional measures of therapeutic efficacy. The purpose of our study was to evaluate the impact of sumatriptan on the quality of life of patients with migraine headaches.Patients and Methods.‐Migraine patients who were given a prescription for sumatriptan completed an SF‐36 questionnaire and a nine‐item pain questionnaire. Six to 9 months later, patients were mailed another copy of the SF‐36 and the nine‐item pain questionnaire. We compared the pretreatment and posttreatment scores for the SF‐36 and for each question of the nine‐item pain questionnaire.Results.‐The pretreatment SF‐36 was completed by 255 patients. The pretreatment pain questionnaire was completed by 86 of these patients. Follow‐up questionnaires were returned by 147 patients (58%). Three of the eight SF‐36 scales: role functioning‐physical, bodily pain, and social functioning showed significant (P<0.05) improvement with treatment. On the nine‐item pain‐specific questionnaire, three items ‐ pain interference with normal work, ability to walk or move about, and enjoyment of life showed statistically significant (P

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508449.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Subjects with tension‐type headache and headache‐free control subjects completed two mental stressor tasks, solving anagrams and mental arithmetic. During the experimental session, measures of heart rate, muscle tension, and subjective stress ratings were recorded. In addition, all subjects completed a week‐long series of questionnaires which monitored headache activity in addition to frequency and intensity of stressful life events. Recurrent tension headache sufferers were found to have higher levels of depression and trait anxiety. Headache and control subjects were not found to respond differently to stressors presented in the laboratory based on measures of EMG, heart rate, or subjective stress ratings, nor were there differences in reports of coping. However, diary questionnaires revealed that headache subjects experienced stressful events more frequently than headache‐free controls. Headache subjects also rated these events as causing more

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508455.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

According to Sjaastad, the pain in cervicogenic headache, a form not recognized by the IHS, is long lasting and always side‐locked unilateral. The frequency of side‐locked unilateral pain (defined here as no change in side from onset) and other characteristics of cervicogenic headache were investigated in 300 outpatients using information collected on standard forms in structured interviews. Three hundred seventy‐four headaches diagnosed according to IHS criteria were identified. Three hundred forty‐eight of these headaches were long‐lasting (duration of more than 4 hours); migraine (65%) followed by tension‐type headache (25%) were the commonest forms. Side‐locked unilaterality was present in 29% (101 of 348), and occurred most frequently in migrainous disorders not fulfilling the criteria (25 of 56, 44.6%). This group differed significantly from the other migraine conditions for longer pain duration (P<0.02) and less frequent nausea, vomiting, photophobia, phonophobia (P<0.0001), and aggravation by physical activity (P<0.02). With these characteristics, this group resembled cervicogenic headache. However, in none of these patients was pain triggered by head or neck movements, and the frequency of head or neck trauma did not differ from other headaches. A more precise definition of clinical criteria for cervicogenic headache vs migraine is, theref

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508461.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Head‐up tilt tests were performed in six cluster headache patients in a bout of attacks, but in a pain‐free interval at the time of investigation; and in eleven controls matched for age, basal blood pressure, and heart rate. A Doppler servomethod was used for a noninvasive, beat‐to‐beat blood pressure determination. There were no significant differences between the cluster headache and control groups for heart rate and systolic blood pressure response to the head‐up tilt. However, the average diastolic blood pressure seemed to drop more after the tilt in the cluster headache group than in the control group; in particular, in the later part of the test. This might suggest a dysfunction of the baroreflex in cluster headache patients in a bout, also outside of attacks, and most probably of the sympathetically‐mediated vasomot

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508465.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Seventeen patients with migraine headaches, occurring at least twice a month, were successfully treated with an ACE inhibitor for prophylaxis. Most were given enalapril, some used lisinopril. Duration of treatment ranged from 3 months to 3 years. Side effects were generally not noted. Cough occurred in four patients. The mechanism of action is unknown. The lack of side effects and the presence of clearly sustained benefit in this small group of migraineurs should prompt further study and use of this class of drugs for prophylaxis.

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508470.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Twenty‐six patients (19 women, 7 men), who suffered from chronic migraine according to IHS criteria, underwent acupuncture. In order to evaluate the long‐term stability of treatment effects, patients documented frequency, duration, and intensity of attacks as well as analgesic intake in a migraine diary, which was kept for 5‐week periods before treatment, immediately after treatment, and 3 years later. Data showed improvement greater than 33% for 18 patients (69%) at posttreatment and 15 patients (58%) at 3‐year follow‐up. Drug intake was reduced to 50% and did not re‐increase until follow‐up. Treatment outcome was associated with personality traits, but not depending on demographic data or severit

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508472.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

The investigation of personality traits of migraineurs with the Minnesota Multiphasic Personality Inventory (MMPI) is an important line of research, but so far has led to diverse conclusions. In this study, the MMPI (Chinese edition) responses of 50 Chinese subjects (10 men, 40 women) with migraine (4 migraine with aura, 46 without aura), during frequent headache attacks were compared with 30 nonheadache healthy control subjects (6 men, 24 women). Statistical analysis was made between the two groups. The results revealed that subjects in the migraine group had significantly higher scores on subtests of neurotic, (hypochondriasis, depression, hysteria, and psychasthenia), schizophrenia, and social introversion (P<0.05 to 0.001). Utilizing the American T‐score, we found the migraine group's MMPI profile was a typical 1.2.3.7 model. These results suggest migraineurs with frequent headache attacks have multiphasic personality abnormalities and partial cerebral function disturbance

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508475.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

摘要:

Effective migraine treatment is clearly the most cost‐effective in terms of both direct and indirect costs. Patient education, behavior changes, and prudent medication selection can minimize costs. Low‐dose aspirin may reduce headache frequency. Among the antidepressant medications used, amitriptyine 25 mg, 3 qhs ($4.16/month) and doxepin 25 mg, 3 qhs ($10.50/month) remain the standard. Imipramine (25 mg, 3 qhs ($3.75/month) is very inexpensive and should replace nortriptyline 25 mg, 3 qhs ($64.29/month) as a second‐line agent. The specific serotonin reuptake inhibitors are expensive and have no proven effect for migraine prevention.Propranolol 80 mg bid ($7.80/month) is inexpensive and frequently a good choice among beta‐blockers. Atenolol 100 mg qd ($27.50/month) is less expensive than long‐acting propranolol 160 mg ($35.56/month) and nadolol 120 mg qd ($43.68/month) with equivalent effectiveness. It is thus recommended as the ong‐acting beta‐blocker of choice. Sustained‐release preparations of verapamil 240 mg qd ($31.98/ month) are twice the cost and less well‐absorbed than the standard preparation of 120 mg bid ($17.62/month).Better information is needed concerning effectiveness and optimal dosing of some older low‐cost medications in the preventive tr

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508479.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY

ISSN:0017-8748    

DOI:10.1111/j.1526-4610.1995.hed3508488.x

出版商:Blackwell Science Inc    

年代:1995

数据来源: WILEY