摘要:

AbstractTwentyfour male patients with sustained myocardial infarction (MI) were studied with 12‐lead ECG and systolic time intervals (STI) 5 months after the acute episode. From the ECGs were calculated the summed voltages of the R wave (σR), the Q wave (σQ), and the ST segment deviation (σST). These ischaemic ECG variables were correlated with the STI parameters of left ventricular function: LVETI, PEP and PEP/LVET. Statistically significant regression equations relating the ECG changes to the STI variables were found in anterior MI, for σST in the entire series, but not in inferior MI. Thus a simple and rapid inspection of the resting 12‐lead ECG gives an indirect but reliable quantitative estimate of left ventricular function in patients with a sustained myocardial infarction.Experimental studies have shown a relation between QRS changes in the ECG and the size of myocardial infarction (MI) (11, 21). As the extent of myocardial damage after MI determines the impairment of left ventricular (LV) function (14, 20, 25), a correlation between QRS changes and the LV performance would be expected. Linear correlation between the summed R wave voltages (σR) and the number of Q waves (Q index), and the angiographically determined LV ejection fraction has been reported in patients with chronic ischaemic heart disease (2, 4). This study looked for a quantitative correlation between the LV performance, as reflected by various systolic time intervals (STI), and ischaemic ECG changes (σR, σQ, and σST) in a group of patients with

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00702.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

AbstractA rocket immunoelectrophoretic method with prepared antisera to rabbit myoglobin has been developed to study the urinary myoglobin excretion in patients with acute myocardial infarction. The method is able to detect a minimum urinary myoglobin concentration of 1—2 mg/l. Urine specimens from 156 patients admitted to the coronary care unit with a provisional diagnosis of acute myocardial infarction were analysed. Seventysix patients proved to have documented myocardial infarction. Twelve of them had at least one positive determination. Four of the 80 without infarction had myoglobinuria. 15 hours elapsed from the time of the initial event of chest pain to the first positive urine specimen. No statistically significant difference could be demonstrated in the mortality in patients with infarction with and without myoglobinuria.The present authors were unable to confirm the high incidence of myoglobinuria in acute myocardial infarction, described previously in other works. The possibility of renal tubular reabsorption of myoglobin as an explanation of this descrepancy is mentioned. Our preliminary results with the estimate of myoglobin in serum with a radioimmunoassay seem to valuable as an index of infarct siz

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00703.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00704.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

AbstractAn improved electrophoretic modification for measuring aspartate aminotransferase (ASAT) isoenzymes is presented. This method fulfils the clinical requirements for sensitivity and allows the detection of 1 U/1 mitochondria ASAT activity at 25°C. The procedure is relatively simple, requiring about one hour for a series of 8 determinations. Mitochondrial ASAT activity was found in all patients suffering from acute myocardial infarction pathological activity was observed for several days longer than that of total serum ASAT enzyme. None of the 25 healthy people studied had mitochondrial ASAT in their serum

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00705.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

摘要:

AbstractSerum MB isoenzyme of creatine kinase is the most specific and sensitive indicator of myocardial infarction. Despite these virtues, its clinical use is handicapped by rapid normalization after the onset of myocardial injury. In patients suffering brain accidents, the increase of serum CK‐MB isoenzymes indicates simultaneous myocardial damage and means poor prognosi

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00706.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00707.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00708.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00709.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1979.tb00691.x

出版商:Blackwell Publishing Ltd    

年代:1979

数据来源: WILEY