| 21. |
REVERSIBILITY OF CEREBRAL SYMPTOMS IN SEVERE HYPERTENSION IN RELATION TO ACUTE ANTIHYPERTENSIVE THERAPY DANISH MULTICENTER STUDY |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 107-110
Allan McNair,
Arne R. Krogsgaard,
Tage Hilden,
Poul Ebbe Nielsen,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08787.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 22. |
HAEMODYNAMIC EFFECTS OF CIGARETTE SMOKING BEFORE AND DURING LONG‐TERM NON‐SELECTIVE AND SELECTIVE BETA‐ADRENERGIC BLOCKADE IN PATIENTS WITH ARTERIAL HYPERTENSION. |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 111-114
Mogens Tangø,
Arne R. Krogsgaard,
Jens Trap‐Jensen,
Jørgen Schläger,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08788.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 23. |
HEMODYNAMIC EFFECTS OF COMBINED BETA‐ADRENOCEPTOR BLOCKADE AND PRECAPILLARY VASODILATATION IN HYPERTENSION |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 115-120
Robert Eggertsen,
Ramon Sivertsson,
Lennart Andrén,
Lennart Hansson,
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摘要:
ABSTRACT.Carvedilol (BM14190) is a new compound with combined properties of nonselective betaadrenoceptor blockade, devoid of ISA, and precapillary vasodilatation. Its acute hemodynamic effects were studied with invasive technique (dye‐dilution using Cardio‐Green) in 10 patients taking 25 mg orally and noninvasive (fore‐arm plethysmography) in 10 patients taking 25 mg and in 10 patients taking 50 mg orally, all with essential hypertension. Significant reductions of systolic and diastolic blood pressures (p<0.05 — 0.001) were observed in all groups. TPR did not change acutely whereas resistance in the fore‐arm was reduced by 16% (p<0.05).When a comparison with propranolol (80 mgx2) was made in a randomized, double‐blind placebo controlled trial comprising 30 patients with essential hypertension, carvedilol acutely reduced blood pressure significantly 13/6 mm Hg (25 mg) and 17/10 mm Hg (50 mg) in contrast to propranolol. Resistance in the fore‐arm (plethysmography) fell significantly with carvedilol 50 mg whereas propranolol caused a significant rise. After 4 weeks both compounds had reduced blood pressure significantly and to the same extent. Blood flow was still reduced with propranolol in contrast to the findings with carvedilol.We conclude that carvedilol given orally has a useful antihypertensive effect both acutely and during prolonged treatment. It has an attractive hemody
ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08789.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 24. |
THE FIRST DOSE HEMODYNAMIC RESPONSES TO VISACOR (ICI 141 ‐ 292) IN ESSENTIAL HYPERTENSION |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 121-125
Per Lund‐Johansen,
Per Omvik,
Helge Haugland,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08790.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 25. |
PHARMACOLOGICAL PROPERTIES OF BETA‐ADRENOCEPTOR BLOCKERS IN RELATION TO THEIR ANTIHYPERTENSIVE EFFECT |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 127-128
Björn Dahlöf,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08791.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 26. |
Is adrenergic betareceptor blockade contraindicated in patients with intermittent claudication? |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 129-132
T.L. Svendsen,
R. Jelnes,
K.H. Tønnesen,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08792.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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| 27. |
EVIDENCE OF THE DEVELOPMENT OF DELAYED‐TYPE AUTOIMMUNITY AGAINST ARTERIAL VESSEL‐WALL ANTIGENS FOLLOWING ACUTE HYPERTENSIVE DAMAGE TO ARTERIAL VESSELS IN RATS. |
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Acta Medica Scandinavica,
Volume 217,
Issue S693,
1985,
Page 133-137
FINN OLSEN,
CARSTEN LAYBOURN,
LARS DRIVSHOLM,
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ISSN:0001-6101
DOI:10.1111/j.0954-6820.1985.tb08793.x
出版商:Blackwell Publishing Ltd
年代:1985
数据来源: WILEY
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