摘要:

SUMMARYUsing a double‐blind and placebo technics, the side‐effects of tablets containing different iron compounds were compared in 1496 subjects. Three separate series, all of which included placebo and ferrous sulphate tablets were studied. The agreement between the results obtained in different series was very good.Ferrous sulphate, ferrous gluconate, ferrous fumarate, and ferrous glycine sulphate had almost the same incidence and type of side‐effects. The incidence was significantly higher than when placebo tablets were

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1966.tb19403.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY

摘要:

SUMMARYThe effect of a number of substances on iron absorption was studied in man using a double radioiron method. The substances studied were carbohydrates, amino acids, inorganic salts, thiamine, and riboflavin.Three carbohydrates (sorbitol, mannitol and xylose) were found to increase the absorption of iron when given in large amounts. This absorption‐promoting effect, however, was accompanied by an increase in side‐effects. Ascorbic acid, which is known to increase iron absorption, was added to iron tablets. The side‐effects of such tablets were higher than those of plain iron tablets containing the same amount of elemental iron. These studies show that it is necessary to study both the absorption and the side‐effects to be able to judge the practical value of an iron prep

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1966.tb19404.x

出版商:Blackwell Publishing Ltd    

年代:1966

数据来源: WILEY