ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03212.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.The prevalence of retinopathy and proteinuria was assessed in 212 and 230 type 1 diabetics in Iceland respectively. They represent 78% and 84% of all such patients identified in the country. Retinopathy was present in 33.5%, background lesions only in 27.4% and more severe retinopathy in 6.1%. After 5–9 years of diabetes (mean 6.9) the prevalence of retinopathy was 18.8%, including 2.1% proliferative, and rose to 76.7% after 20 years or more of diabetes (mean 26.7), including 16.2% in the proliferative stage. Blindness was found in 2.4% of the patients. Diabetics diagnosed at the age of 0–19 years had a lower prevalence of retinopathy during their first 20 years of diabetes than those diagnosed later in life (p<0.05). Proteinuria was present in 14%, intermittent in 10% and continuous in 4%. After 10 years or more of diabetes (mean 19.3) the prevalence of intermittent and continuous proteinuria was 13.0% and 8.3%, respectiv

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03213.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.The increase in blood glucose in insulin‐dependent diabetics after different fruit meals was investigated. Apple, banana and orange loads were compared with an equal amount of glucose dissolved in water. The postprandial blood glucose responses to pure glucose, apple and banana were almost identical, while the response after orange was somewhat weaker. We therefore conclude that though these fruits contain considerable amounts of fructose, they represent an important source of rapidly absorbable carbohydrate and should mainly be used in mixed meal

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03214.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.Four patients with hemolytic uremic syndrome (HUS) and seven with thrombotic thrombocytopenic purpura (TTP) were treated with infusions of fresh frozen plasma (FFP). In one patient with HUS and Ave patients with TTP this treatment was combined with plasma exchange (PE). The additional treatment varied; corticosteroids, antiplatelet drugs, heparin and blood exchange. All but one patient recovered completely in spite of severe illness with uremia, oliguria and/or cerebral symptoms during the acute phase. The results were surprisingly good in comparison with other published series. The success must in the first place be attributed to early diagnosis and to the infusions of FFP. PE seemed to potentiate the effect of FFP.

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03215.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.Hospital records of 256 patients discharged with a diagnosis of agranulocytosis during 1973–78 in the Stockholm County region were reviewed. In 84 cases the neutropenia was probably caused by drugs other than cytostatics, giving an annual incidence of 0.009%c. The commonest drugs were sulfonamides, thyreostatics and thenalidine. Metamizole (Dipyrone), previously the commonest cause of drug‐induced neutropenia in Sweden, has not been marketed since 1973 and, as a result, only two cases were seen (the drug had been obtained abroad). Comparison of the number of cases of neutropenia with drug sales showed the highest frequency for thenalidine, followed by thyreostatics, penicillamine and sulfonamides, in that order. Only about 35% of the cases had been reported to the authorities. Nine (11%) of the patients died. It is concluded that the pattern of drugs causing neutropenia has changed in Sweden since the studies from the latter half of the 60s and that early detection of this side‐effect requires directed and continuous follow‐up

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03216.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.Plasma fibrinogen, soluble fibrin monomer complexes (FMM) in plasma and fibrin degradation products (FDP) in serum were studied in 31 patients with acute myocardial infarction (MI) during their stay in hospital. The ECGs of 15 patients indicated a high risk of recurrent MI. Seven patients had a recurrent MI within three months. No correlation could be found between plasma fibrinogen or FMM and reinfarction, but FDP was increased in six of the seven patients with reinfarction compared to six of the 24 without (p<0.01).

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03217.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.Quantitative liver function was estimated by determination of the galactose elimination capacity (GEC) in 29 patients with steatosis, 50 with cirrhosis and 42 control patients without clinical history or signs of liver disease. In patients with steatosis and cirrhosis, clinical signs of liver disease were recorded and the most common liver tests were carried out. The degree of histological changes was investigated in needle liver biopsies performed in a close relation to the GEC determinations. A positive correlation between GEC and body weight and body surface area was observed in all three patient groups. GEC (absolute value, per kg body weight and per m2body surface area) was significantly different (p<0.001) between the three groups, but was without diagnostic value due to a broad scattering of results in each group. This may be due to methodological errors in the determination of GEC, but also to the large biological variation in normal man and the pathophysiological conditions in patients with liver disease. Neither in patients with steatosis nor in patients with cirrhosis could significant relations be found between GEC and clinical signs of liver disease or the degree of severity of histological changes assessed semiquantitatively. In patients with cirrhosis but not in patients with steatosis, GEC was significantly correlated with the majority of the most commonly utilized liver tests.

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03218.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.The quantitative liver function, measured by the galactose elimination capacity (GEC), was determined repeatedly in 44 patients with cirrhosis during the course of the disease. After a median observation period of 57 months (range 28–85) 17 had died from liver insufficiency. GEC was found to be of prognostic value, as classification of the patient series on the basis of the median value of two extreme prognostic groups indicated that the survival of patients with GEC>1.37 mmol·min‐1at entry was significantly larger than of patients with GEC below that value (p<0.05). The prognostic values of serum albumin and prothrombin were of the same order of magnitude. At repeated examinations during the course of the disease, the survivors always had higher GEC values than those who died from liver insufficiency. Among those who survived and those who died there were patients with both increasing and decreasing GEC values, but no significant changes were observed within the groups. The individual changes in GEC can result from changes in the balance between liver cell necrosis and regeneration, but the possibility cannot be excluded that changes are due to methodological problems in the determination of the quantitative liver function as measured by

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03219.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.In a retrospective study covering 14 years (1962–75), the annual incidence of stroke in the isolated population of the Faroes (approx. 40000 inhabitants) was 45.7 per 100000 in the age range 15–65 years. The type of stroke was subarachnoid haemorrhage in 34 cases, and other types of stroke were found in 111 cases. The incidence of stroke in this study was lower than in Denmark, Finland, Sweden and the USA. There was no significant sex difference (males 43.0, females 48.3) (p>0.05). It is pointed out that dietary habits on the Faroes differ from those in other Scandinavian countr

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03220.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY

摘要:

ABSTRACT.The purpose of the present study was to examine the effect of phenaeetin consumption and its restriction on the mortality from nephropathy. Changes in this mortality in Finland during 1951–77 were investigated. The second part of the study was concerned with the frequency of papillary necrosis in cases autopsied in the Department of Medicine, Turku University Central Hospital, during 1952–79. These figures were studied in relation to increased phenaeetin consumption after World War II, its restriction in 1962 and its complete banning in 1965. Both the epidemiologic survey of the mortality from nephropathy in Finland and the autopsies showed a clear and strong correlation both with increased phenaeetin consumption and with its discontinuation. The banning of phenaeetin led within 2–4 years to a decline in the mortality from nephropathy to its pre‐phenaceti

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1982.tb03221.x

出版商:Blackwell Publishing Ltd    

年代:1982

数据来源: WILEY