ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02705.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02706.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02707.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTOral body temperature was measured in 816 men, 57 and 67 years old, sampled from the general population of Göteborg, Sweden, and 22 physically highly active men, sampled on clinical grounds. The measurements were taken in the morning for 14 months. After adding 0.3°C to the readings to make them comparable with rectal readings, the mean body temperature was 36.8±0.4°C. There was a seasonal variation with a peak during the winter and a trough during the summer. Body temperature was inversely correlated with height and positively correlated with weight and body fat but not with lean body mass. High physical activity and sensitivity to heat were associated with a higher than average body temperature. Sensitivity to cold was associated with a lower than average body temperature. Smoking prior to the measurements did not appear to affect body temperat

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02708.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTTo study prospectively the effects of a brief febrile viral infection on parameters of muscle and circulatory function, seven volunteers were inoculated with sandfly fever virus and two control subjects with sterile saline. During but not after fever, decreased isometric and dynamic strength and endurance were recorded in various muscles. Impairment could not be explained by altered activities of relevant muscle enzymes in serum or muscle tissue or by altered muscle ultrastructure, but correlated with the severity of perceived symptoms, including myalgia, as rated by each subject. Compared to baseline, cardiac stroke volume was lower during and after fever. During fever, an increased heart rate maintained cardiac output at pre‐inoculation values, whereas cardiac output fell in early convalescence. This decrease in cardiac output correlated significantly with the severity of fever. Thus, in brief viral infections a transient impairment of muscle performance capacity is correlated to subjective symptoms such as myalgia, rather than to fever, whereas a decreased cardiac output following such infections seems to be associated with the fever reactio

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02709.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTAt a health survey of 819 middle‐aged, 47–54‐year‐old, males and females in a Swedish urban area with a participation rate of 70%, the prevalence of glucose intolerance (GI) was 6.2%, 51 subjects (7.0% of females and 5.3% of males), as the result of two subsequent 75 g oral glucose tolerance tests according to the WHO criteria. In comparison with normoglycemic subjects from the same health survey, with both fasting and 2‐hour glucose values<5.0 mmol·I‐1, the GI group was characterized by higher mean relative body mass index, higher mean blood pressure and rate of hypertension, higher rate of low‐degree physical activity during leisure and had more often a family history of diabetes in first‐degree relatives. Smoking was less prevalent in GI subjects. Hypertension was more frequent in obese (relative body mass index (BMI) 120–150%) GI subjects than NGT subjects. Finally, comparison of all GI subjects with all normoglycemic subjects of the survey, with use of analysis of covariance, showed that mean systolic and diastolic blood pressures were higher in GI subjects, independently of age, BM

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02710.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTGlucose tolerance and reported physical leisure time activity were studied in middle‐aged, 47–54 years old, subjects in a health survey. The mean 2‐hour blood glucose value after 75 g oral glucose tolerance tests was higher (p<0.001) in 682 subjects with a lower degree of leisure time activity than in 125 subjects who were regularly active at least 2–3 hours per week. The mean 2‐hour glucose values in the inactive and active groups, respectively, were 4.61 and 4.09 mmol·1‐1after adjustment for the influence of age, body mass index, smoking and physical job activity by analysis of covariance. The difference between adjusted mean 2‐hour glucose values was also significant (p<0.001) in the subgroups of 280 low leisure time activity males (4.53 mmol·1‐1) and 91 active males (3.93 mmol·1‐1). Thus, a relation between physical leisure time inactivity and raised post load blood glucose values seems to exist in th

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02711.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTSystolic time intervals (STI) and echocardiography were recorded in 133 (70 men, 63 women) newly diagnosed non‐insulin‐dependent diabetics aged 45–64 years and in 144 (62 men, 82 women) non‐diabetic control subjects of the same age. Both male and female diabetics had significantly increased pre‐ejection period/left ventricular ejection time ratio (PEP/LVET) in STI as compared with the respective non‐diabetic control subjects. Male diabetics showed a reduced ejection fraction (EF) in echocardiography, but no significant difference was found in this respect between female diabetics and controls. A significant negative correlation was found between 2‐hour postglucose serum insulin level and EF in male and female diabetics. After adjusting for the effect of age, coronary heart disease, hypertension, obesity and haemoglobin concentration, male diabetics still had a higher PEP/LVET ratio and a lower EF than male controls. In women, no significant differences were found between diabetics and controls in the PEP/LVET ratio or EF adjusted for the above factors. The results of this study are compatible with the view that impaired left ventricular function may be an early phenomenon in the clinical course of non‐insulin‐d

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02712.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTOne hundred and fifty‐four patients, who had been subjected to phlebography 5–8 years previously because of clinical suspicion of deep venous thrombosis (DVT), were investigated to evaluate the frequency of deep venous insufficiency (DVI). The evaluation included clinical examination, registration of subjective complaints and objective measurements with plethysmography, venous pressure and Doppler ultrasound. DVT had been present in 75 legs. There were no statistically significant differences between legs with and without earlier DVT apart from more venous outflow obstruction in the former. DVI was as common after calf vein thrombosis as after more proximal DVT. DVI was more frequent in elderly patients and in patients with a history of previous DVI or DVT. The sufficiency of the popliteal vein seemed to be of great importance in the development of DVI. More than one third of legs without DVT had developed DVI at follow

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02713.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY

摘要:

ABSTRACTFollowing exposure to kaolin, plasma samples were assayed for total prekallikrein/kallikrein activity in 19 patients with rheumatoid arthritis (RA), 39 patients with RA complicated by amyloidosis, 13 patients with nonamyloid nephropathy and 54 healthy subjects. Increased total kallikrein activity was found in RA patients with amyloidosis and in patients with nonamyloid nephropathy. The concentrations of the plasma kallikrein inhibitors Cl‐inactivator and α2‐macroglobulin were normal in RA patients without amyloidosis, whereas they were increased in patients with amyloidosis as well as in patients with nonamyloid nephropathy. The results suggest that the increased activity of plasma kaolinstimulated kallikrein in RA patients with amyloidosis is due to the nephropathy per se and probably reflects increased levels of prekallik

ISSN:0001-6101    

DOI:10.1111/j.0954-6820.1985.tb02714.x

出版商:Blackwell Publishing Ltd    

年代:1985

数据来源: WILEY