ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01507.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryFour radioimmunoassay techniques, two conventional and two sandwich, have been used to measure circulating IgE levels in 100 sera. The test sera had IgE levels ranging From 1.0 to 20,000 u/ml, and each was measured at live dilutions, ranging from threefold to 400‐fold. The same IgE standards were used throughout, and the optimal range for each assay was determined by assessing data for quality control sera and the WHO standard 69/204. To be of general use in the United Kingdom an IgE test must measure accurately levels as low as 20‐30 u IgE/ml. The Phadebas RIST method failed to meet this criterion, and of the remaining tests the double antibody method had the most useful operating range and produced the most reliable results. However, the double antibody method is not available commercially and so, for the majority of laboratories, the Phadebas PRIST technique should be the method cho

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01508.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummarySeventy‐six children aged 5 months to 15 years who exhibited a net weal of 3.0 mm or greater to a puncture skin test with one or more of fourteen foods were subjected to double‐blind food challenge. Confirmed reactions to double‐blind food challenge were found to occur only with peanut, milk, egg and soybean. Puncture skin tests with 1:20 w/v concentration of food extracts identified all subjects who exhibited an adverse reaction during the double‐blind food challenge. Performance of intradermal skin tests did not identify any additional subjects who reacted clinically to double‐blind food

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01509.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryElevated levels of serum immunoglobulin E (IgE) are found in many parasitic diseases. In order to determine the influence ofEntamoeba histolyticaon IgE levels of clinically symptomatic patients with intestinal amoebiasis, a controlled study was performed. There was no difference between the serum IgE values from Brazilian patients with amoebiasis and those from age‐, race‐ and sex‐matched normal Brazilian controls. Based also on our previous similar studies on giardiasis and Chagas’ disease, we conclude that protozoan infections do not elevate serum IgE

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01510.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryIn Finland occupational asthma caused by protein allergens and reactive chemicals present in the air of work environments is increasing. This communication describes provocative challenge tests and methods for measuring exposure under simulated work conditions. The importance of lung function measurements during non‐exposure and placebo periods is stressed. Especially late reactions are difficult to assess because of the great circadian variation in the lung function parameters of asthmatics. For a positive challenge test, a decrease in peak flow values of at least 15% and a clear deviation from normal circadian variation and placebo periods is required. The allergens of vegetable or animal origin primarily affect patients with an atopic constitution. Chemical allergens seem to attack all exposed workers in the same way. The report lists the occupations with risk for asthma and refers to the population at risk; bakers seem to be the group with the most risk. The importance of early diagnosis, removal of the worker from exposure and improvement of the hygienic aspects of the work environment are stresse

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01511.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryPrecipitating antibodies towards antigens associated with farmer's lung disease were studied in Finnish dairy farming and non‐farming rural populations and the results were compared to those of serum samples of patients suspected of having a fungal allergy. The antigen panel consisted ofAspergillus fumigatus, Micropolyspora faeniandThermoactinomyces vulgaris. All three microbes seemed to be important environmental inducers of antibody formation. The prevalence of antibodies towards all of them was higher in the patient group. The presence ofA. fumigatusandT. vulgarisantibodies correlated best with the occurrence of respiratory disease. The difference inM. faeniantibody prevalence between patients and the control group was less significant.The results suggest that in Finland the relative importance of those microorganisms associated with farmer's lung disease may be different from that reported from other countrie

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01512.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryA simplified version of the Hirst automatic volumetric spore trap has been developed in Derby for aerobiological studies. In comparative trials, the numbers of spores retained by the Morrow Brown trap were similar in the case of larger spores such as Alternaria (102%), rather higher in the case of grass pollen (136%) and considerably higher (166–201%) for very small spores such as Sporobolomyces and Tilletiopsis. Impaction efficiency has been improved by using a narrower slit. The trap designed in Derby is simple to produce and presents advantages in design over the Hirst versio

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01513.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryIn order to determine whether a sampling site in the centre of Derby, where air sampling had been carried out for five summers, really provided valid aerobiological data for the surrounding area, eight identical volumetric spore traps were operated simultaneously during the summer of 1969 at various sites up to 56 km from Derby, For most pollen and spore types, total numbers and seasonal pattern at all the sampling sites were found to be similar, although a few extreme and unexpected variations were noted. Figures varied somewhat in different types of site, and local effects are emphasized.

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01514.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY

摘要:

SummaryThe air spora of two sites on the east coast of Britain and one on the west coast were compared with each other and with the regular sampling site in Derby by the simultaneous operation of volumetric spore traps. Concentrations of airborne spores and pollen were found to be usually less at the coastal sites tham in Derby. The effect of wind direction was shown to be important at coastal sites because daily counts often showed rises and falls corresponding to off‐ and on‐shore winds respectively. Counts at the west coast site were nearly always lower than those on the east. These findings, together with the prevalence of westerly winds over Britain and the different land use in the east and west, suggest that fewer airborne allergens may be encountered on the west co

ISSN:0954-7894    

DOI:10.1111/j.1365-2222.1978.tb01515.x

出版商:Blackwell Publishing Ltd    

年代:1978

数据来源: WILEY