摘要:

Two immunoglobulin‐producing lines of normal lymphoblastoid cells have been established from cultures of two human astrocytomata. These had the same characteristics as lymphoblastoid lines derived from normal human lymphoid tissue or peripheral blood. It is concluded that the lymphoblastoid lines are derivates of non‐neoplastic lymphoid cells (perhaps of the B series), which were present as an infiltrate within the astrocytomata. Furthermore, the slow emergence of the lymphoblastoid cells in culture, their continuing requirement for feeder cells and their production of monoclonal rather that heteroclonal immunoglobulin are attributed to an artefact of growth conditi

ISSN:0365-4184    

DOI:10.1111/j.1699-0463.1976.tb00113.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Vascular ingrowth into the injured area of a partially crushed gastrocnemius muscle was studied by micro‐angiography 2 to 14 days after the trauma in 40 rats treated by mobilization or immobilization. In mobilized muscles, the sprouting of new capillaries occurred more rapidly and intensively than in injured muscles treated by immobilization. The sequence of events was found to be slightly delayed if mobilization was started after immobilization for two days. The speed and intensity of tissue repair, as studied histologically, was directly correlated with vascular ingrowth, especially during the first wee

ISSN:0365-4184    

DOI:10.1111/j.1699-0463.1976.tb00114.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

Using ultracentrifugation, compact bone from a growing 15 years old man was separated into three fractions with different degrees of mineralization. The finely powdered material was fractionated in a density gradient of acetone and bromoform in varying proportions. The glycosaminoglycans were isolated after papain digestion of the tissue fractions. The glycosaminoglycan elution profiles from CPC‐cellulose microcolumns indicated the presence of chondroitin‐4‐sulphate and, possibly, minor traces of hyaluronic acid. The degree of sulphatation was the same in all three fractions, while the total amount and molecular size of the glycosaminoglycans decreased somewhat with increasing degree of mineralization. The glycosaminoglycans of the tissue fractions were also extracted with 4 M guanidinium chloride and then purified chromatographically on DEAE. Gel chromatography of the isolated material showed three different peaks, two probably representing low molecular weight proteoglycans. The proportion of intermediate molecular size material increased with increasing degree of mineralization. The results are discussed briefly in relation to the mineralization pr

ISSN:0365-4184    

DOI:10.1111/j.1699-0463.1976.tb00115.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY

摘要:

A case report of a girl with two foetal rhabdomyomas is presented. One tumour was a small cutaneous lesion present at birth in the left thigh and the other was located in the chest wall deeply in the subcutaneous tissue and attached to the adjacent intercostal muscle. The patient also had the naevoid basal cell carcinoma syndrome which lends credence to the opinion that foetal rhabdomyoma is a malformation rather than a true neoplasm.

ISSN:0365-4184    

DOI:10.1111/j.1699-0463.1976.tb00116.x

出版商:Blackwell Publishing Ltd    

年代:1976

数据来源: WILEY