摘要:

The clinicopathologic features and problems in classification and diagnosis of the pancreatic neoplasms with abundant mucus production are presented. In this article, the various reported concepts and terminology of these mucus-producing pancreatic tumors are summarized, and the differences between intraductal papillary-mucinous tumors and mutinous cystic tumors are specifically discussed. Intraductal papillary-mutinous tumors show diffuse or segmental dilatation of the pancreatic ducts with intraductal papillary growth. Mucinous cystic tumors are mucus-producing tumors showing cyst formation, which is often accompanied by intracystic papillary projections and “ovarian-type” stroma. Intraductal papillary-mucinous tumors occur most often in the pancreatic head of elderly men, whereas mucinous cystic tumors typically occur in the pancreatic tail or body of middle-aged women. Histologically, these tumors show a wide cytologic spectrum from benign to borderline to malignant. These tumors pursue an indolent clinical course compared with conventional ductal carcinoma of the pancreas. Mucinous cystadenocarcinomas have a higher malignant potential than intraductal papillary-mucinous adenocarcinomas, yet these tumors recur infrequently if they are excised completely. Because of the differences in clinicopathologic features, these tumors should be clearly separated from conventional ductal carcinoma of the pancreas.

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

The common sources of ionizing radiation exposure to the thyroid gland in humans are accidental environmental exposure and medical, therapeutic, or diagnostic irradiation. Radiation often induces notable histologic changes in the thyroid tissue and is a well-established risk factor for benign and malignant thyroid tumors. In this paper, we review the acute and chronic histologic changes in the thyroid gland subjected to irradiation, and characterize benign thyroid nodules and malignant tumors arising after exposure, with particular emphasis on thyroid lesions in the population exposed to ionizing radiation as a result of the Chernobyl nuclear accident.

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

On Sentinel-node biopsy to avoid axillary dissection in breast cancer with clinically negative lymph nodes. Veronesi U, Paganelli P, Galimberti V, Viale G, Ziurrida S, Bedoni M, Costa A, de Cicco C, Geraghty JG, Luini A, Sacchini V, Veronesi P.By studying the first draining lymph node of a tumor field, a sentinel lymph node biopsy can serve as an indicator of the nodal status of the rest of the lymphatic drainage, and unnecessary regional lymph node dissection can be avoided in sentinel node-negative patients undergoing curative surgery for cancer. This technique has already been widely applied in the management of patients with malignant melanoma. This commentary explains why more data are required before the procedure can be accepted as the standard care in the management of breast cancer

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

On Atypical teratoid/rhabdoid tumor of the central nervous system: A highly malignant tumor of infancy and childhood frequently mistaken for medulloblastoma. Burger P, Yu I-T, Tihan T, Friedman H, Strother D, Kepner J, Duffner P, Kun L, Perlman EAtypical teratoid/rhabdoid tumor of the central nervous system has successfully emerged from inclusion as a form of medulloblastoma to a distinctive entity over the past decade. This event has more than nosological importance in that the five-year survival rate for medulloblastoma is considerably better than for atypical teratoid/rhabdoid tumor which is uniformly poor. The relationship of the central nervous system neoplasm to malignant rhabdoid tumor of the kidney, beyond sharing some histologic features and a genetic linkage to chromosome 22, needs further exploration.

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

摘要:

On Sertoli cell tumors of the testis, not otherwise specified: A clinicopathologic analysis of 60 cases. Young RH, Koelliker DD, Scully RE.This commentary discusses the strengths and weakness of the series of 60 cases of testicular Sertoli cell tumor (not otherwise specified) reported by Young and colleagues. The reviewers propose that sclerosing Sertoli cell tumor is merely a morphologic variant of Sertoli cell tumor with no distinctive clinical features. On the other hand, the large cell calcifying variant is clinically distinctive, and shows association with Carney complex.

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID

ISSN:1072-4109    

出版商:OVID    

年代:1999

数据来源: OVID